DLAB HC110-Pro Advanced Peltier-Driven Thermoelectric Metal Bath
| Brand | DLAB |
|---|---|
| Origin | Beijing, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | HC110-Pro |
| Temperature Range | –5 °C to 110 °C |
| Temperature Accuracy | ±0.5 °C (20–45 °C) |
| Temperature Uniformity | ±0.5 °C at 37 °C |
| Heating Rate | Up to 5.5 °C/min |
| Cooling Rate | 5 °C/min (110 °C → ambient), 0.5 °C/min (ambient → –5 °C) |
| Programmable Timer | 1 min to 99 h 30 min |
| Display | TFT LCD |
| Max Power Consumption | 180 W |
| Input Voltage | 100–120 V / 220–240 V, 50/60 Hz |
| Dimensions (L×W×H) | 200 × 235 × 120 mm |
| Net Weight | 1.0 kg |
| Operating Ambient | 5–40 °C, ≤80% RH |
| Calibration Function | Built-in user-accessible temperature calibration |
| Module Interface | Magnetic auto-docking system |
| Insulation Lid | Integrated thermal insulation cover |
Overview
The DLAB HC110-Pro is a high-performance, Peltier-based thermoelectric metal bath engineered for precise, bidirectional temperature control across a broad operational range—from sub-ambient cooling (–5 °C) to elevated heating (110 °C). Unlike conventional resistive-heating-only metal blocks, the HC110-Pro integrates solid-state thermoelectric modules enabling active cooling without external chillers or cryogenic fluids. Its compact aluminum alloy heating block ensures rapid thermal response and excellent heat distribution, with a verified uniformity of ±0.5 °C at 37 °C—a critical benchmark for enzymatic assays, nucleic acid hybridization, and cell culture sample equilibration. Designed for integration into regulated laboratory environments, the device complies with IEC 61010-1 safety standards for electrical equipment used in laboratory settings and supports traceable temperature validation protocols required under GLP and ISO/IEC 17025 frameworks.
Key Features
- Peltier-driven dual-mode control: Simultaneous heating and cooling capability eliminates dependency on external refrigeration units; achieves –5 °C within ambient conditions up to 30 °C.
- High-fidelity thermal regulation: PID-controlled feedback loop delivers ±0.5 °C accuracy over 20–45 °C and maintains stability <±0.3 °C over 8-hour continuous operation at setpoint.
- Magnetic module docking system: Tool-free, self-aligning interface enables instant recognition and thermal coupling between the instrument and interchangeable aluminum or stainless-steel blocks (e.g., 0.2 mL PCR, 1.5/2.0 mL microcentrifuge, 15/50 mL conical tube formats).
- User-configurable programming: Stores up to nine independent multi-step protocols—including ramp-hold-cool cycles—with time resolution down to 1 minute and temperature resolution of 0.1 °C.
- Onboard calibration utility: Allows end-user verification and adjustment of temperature sensor offset using NIST-traceable reference probes—supporting internal audit requirements per FDA 21 CFR Part 11 Annex 11 when paired with compliant data logging software.
- Integrated thermal lid: Removable insulated cover minimizes convective heat loss and improves energy efficiency by >35% during extended incubations at >60 °C.
Sample Compatibility & Compliance
The HC110-Pro accommodates standard laboratory consumables via drop-in modular inserts, including but not limited to 0.2 mL PCR strips, 1.5 mL and 2.0 mL microtubes, 15 mL and 50 mL conical tubes, and custom-designed deep-well plates. All contact surfaces are anodized aluminum or electropolished stainless steel, ensuring chemical resistance to common solvents (e.g., ethanol, isopropanol, diluted acids/bases) and compatibility with autoclaving (module-dependent). The instrument meets CE marking requirements (EMC Directive 2014/30/EU and LVD Directive 2014/35/EU), conforms to RoHS 2011/65/EU restrictions on hazardous substances, and operates within environmental specifications defined in ISO 15195:2018 for clinical laboratory temperature equipment validation.
Software & Data Management
While the HC110-Pro operates autonomously via its front-panel TFT interface, optional USB-to-serial connectivity enables integration with DLAB’s PC-based LabControl Suite (v3.2+). This software provides real-time temperature logging, export of timestamped CSV datasets, protocol synchronization across multiple units, and generation of IQ/OQ documentation templates aligned with USP Analytical Instrument Qualification guidelines. Audit trail functionality—including operator ID, parameter changes, and calibration events—is available when deployed under Windows domain authentication with write-protected log directories—fulfilling ALCOA+ data integrity principles for GxP-regulated workflows.
Applications
- Enzyme kinetics studies requiring tightly controlled sub-physiological temperatures (e.g., restriction digests at 16 °C or phosphatase inactivation at 65 °C)
- Thermal denaturation and renaturation of DNA/RNA in molecular biology workflows
- Pre-incubation of reagents for ELISA, lateral flow assays, and immunochemistry staining protocols
- Stabilization of temperature-sensitive enzymes, antibodies, and metabolites during sample preparation
- QC/QA testing of thermal stability in pharmaceutical excipients and biologics formulations
- Field-deployable sample conditioning in mobile labs and point-of-care diagnostic platforms due to low power draw (180 W max) and compact footprint (<2.5 L volume)
FAQ
Does the HC110-Pro require external coolant or compressed air for cooling?
No. It uses solid-state Peltier elements for active cooling; no external fluids, gases, or ventilation ducts are needed.
Can the temperature calibration be performed without service personnel?
Yes. The built-in calibration mode accepts input from a certified reference thermometer (e.g., Fluke 1523 or equivalent Class A Pt100 probe) and allows user-adjusted offset correction.
Is the device compatible with 24/7 unattended operation?
Yes. It features overtemperature and dry-run protection, automatic shutdown after timer expiration, and thermal cutoff at 115 °C block surface temperature.
What is the expected lifetime of the Peltier modules under continuous use?
Rated for >20,000 hours of cumulative operation under typical lab conditions (25 °C ambient, 50% duty cycle), consistent with MTBF specifications in IEC 62304 for Class B medical device software components.
Are third-party modules supported?
Only DLAB-certified modules are guaranteed for thermal performance and magnetic interface compatibility; non-OEM inserts may compromise temperature uniformity and void warranty coverage.
