Jinye RE-5299 Rotary Evaporator

Overview

The Jinye RE-5299 Rotary Evaporator is an engineered laboratory system designed for efficient solvent removal, concentration, and gentle compound recovery under reduced pressure. It operates on the principle of rotary evaporation—combining controlled sample rotation, precise bath temperature regulation, vacuum-assisted vapor pressure reduction, and high-efficiency condensation—to maximize evaporation rate while minimizing thermal degradation. The unit integrates a vertically oriented, double-layer jacketed condenser for optimal heat exchange, a digitally regulated DC drive for smooth and stable rotation across its full 0–130 rpm range, and a motorized lift mechanism enabling reproducible positioning of the evaporation flask relative to the heating bath. Its digital PID temperature controller maintains setpoint accuracy within ±1 °C across the 0–99 °C operating range, ensuring consistent thermal input during sensitive applications such as thermolabile natural product isolation or pharmaceutical intermediate purification.

Key Features

• Motorized vertical lift system with limit switches and overload protection, enabling repeatable immersion depth control and safe operation during vacuum transitions
• Digital speed regulation via microprocessor-controlled DC motor—provides stable rotational torque even at low speeds (e.g., <10 rpm), critical for viscous or foaming samples
• Vertical top-entry condenser with 0.12 m² effective cooling surface area, constructed from borosilicate glass (3.3) and equipped with dual coolant channels for enhanced reflux efficiency
• Heating bath with stainless steel housing, PTFE-coated immersion heater, and integrated digital temperature display—calibrated for ambient-to-99 °C operation with ±1 °C stability
• Standard 24/29 ground-glass joints throughout the system (rotating flask, condenser, collection flask, and vacuum adapter) ensure leak-tight, interchangeable, and chemically resistant connections
• Integrated vacuum seal monitoring via O-ring compression design and optional vacuum gauge port for real-time pressure feedback integration

Sample Compatibility & Compliance

The RE-5299 accommodates standard pear-shaped rotating flasks (250 mL) and round-bottom collection flasks (500 mL), both featuring 24/29 taper joints compatible with common lab glassware accessories—including extension adapters, cold traps, and inert gas inlets. Its all-glass fluid path (excluding motor housing and bath shell) ensures compatibility with organic solvents (e.g., ethyl acetate, dichloromethane, methanol), aqueous buffers, and mild acidic/basic solutions. The system meets general requirements for GLP-compliant documentation workflows when paired with external data loggers; while not pre-certified to FDA 21 CFR Part 11, its analog controls and mechanical repeatability support audit-ready operational consistency in QC environments governed by ISO/IEC 17025 or USP .

Software & Data Management

The RE-5299 operates via standalone hardware controls—no embedded firmware or proprietary software is required. All operational parameters (rotation speed, bath temperature, lift position) are manually set and visually monitored using front-panel LED displays and calibrated dials. For laboratories requiring traceable process records, the unit supports integration with third-party data acquisition systems via analog output signals (0–5 V or 4–20 mA) for temperature and RPM—enabling time-stamped logging in LIMS or ELN platforms. Optional vacuum controllers with RS-485 or USB interfaces may be added externally to extend automation capabilities without modifying the base instrument architecture.

Applications

• Concentration of heat-sensitive biomolecules (e.g., peptides, enzymes, plant extracts) in biopharmaceutical R&D labs
• Solvent recovery and crude product enrichment in fine chemical synthesis workflows
• Removal of low-boiling solvents prior to lyophilization or crystallization steps in API development
• Parallel batch processing in academic teaching labs—configured with standardized joint sizes for rapid setup and cleaning
• Preparative-scale purification where moderate throughput (up to 500 mL/batch) and thermal precision outweigh ultra-high-vacuum requirements

FAQ

What vacuum level is recommended for optimal performance with the RE-5299?
A stable vacuum between 10–100 mbar (7.5–75 Torr) is typically sufficient for most solvent removal tasks; lower pressures may be used for high-boiling-point solvents but require compatible vacuum pumps and cold traps.
Is the heating bath compatible with silicone oil or water as heat transfer media?
Yes—the stainless steel bath accepts both water (for temperatures ≤95 °C) and silicone oil (for extended range up to 99 °C); oil use requires periodic viscosity checks and replacement per manufacturer guidelines.
Can the RE-5299 be operated continuously for extended periods (e.g., overnight)?
Continuous unattended operation is not recommended without additional safeguards; integration with external vacuum failure alarms, temperature cutoff relays, or programmable logic controllers is advised for extended runs.
Are replacement parts such as gaskets, O-rings, and glass components available through Jinye?
Yes—standardized 24/29 joint O-rings (Viton® or silicone), PTFE stopcocks, and condenser sleeves are stocked and supplied directly by Jinye’s Shanghai manufacturing facility with documented material certifications.
Does the unit comply with CE or UL safety standards?
The RE-5299 conforms to IEC 61010-1:2010 for electrical safety in laboratory equipment; CE marking is available upon request for export configurations meeting EU Declaration of Conformity requirements.