Shanghai Yarong RE-52CS-1 Rotary Evaporator
| Brand | Jinye |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | RE-52CS-1 |
| Rotational Speed | 0–120 rpm (electronic speed control) |
| Temperature Control Range | Ambient to 99 °C |
| Temperature Control Accuracy | ±1 °C |
| Condenser Type | Vertical condenser |
| Condensing Area | 0.15 m² |
| Flask Capacity | 1 L rotating flask (29/32 standard taper), 500 mL collection flask (24/29 standard taper) |
Overview
The Shanghai Yarong RE-52CS-1 Rotary Evaporator is a precision-engineered benchtop purification system designed for efficient solvent removal, concentration, and recovery under reduced pressure. Operating on the principle of rotary evaporation—where simultaneous rotation, vacuum application, and controlled heating maximize surface area and heat transfer—the RE-52CS-1 enables rapid, gentle evaporation of thermally sensitive compounds without degradation. Its integrated design pairs a variable-speed rotating assembly with a vertical condenser of 0.15 m² effective cooling surface, ensuring high condensation efficiency across a broad range of solvents including water, ethanol, acetone, ethyl acetate, and chloroform. The system is optimized for use with the B-260 constant-temperature water bath (sold separately), which provides stable thermal input within an ambient-to-99 °C operating envelope and maintains temperature stability within ±1 °C—critical for reproducible distillation outcomes in regulated environments.
Key Features
- Electronic stepless speed control (0–120 rpm) with digital display for precise rotational adjustment and process repeatability
- Vertical double-layer glass condenser with high-efficiency coolant path geometry and 0.15 m² active condensing surface
- Stainless steel mainframe with corrosion-resistant coating and ergonomic height-adjustable lifting mechanism
- PTFE-coated sealing joints and ground-glass interfaces (29/32 and 24/29 standard tapers) for vacuum integrity and chemical compatibility
- Integrated vacuum-tight stopcock and quick-release vapor duct for rapid system venting and flask exchange
- Thermally insulated water bath interface compatible with B-260 and equivalent thermostatic baths (external)
Sample Compatibility & Compliance
The RE-52CS-1 accommodates standard laboratory glassware conforming to ISO 385 and ASTM E287 specifications for volumetric and conical flasks. Its 1 L rotating flask (29/32 taper) and 500 mL collection flask (24/29 taper) support batch volumes from 200 mL to 800 mL, enabling scalable operation across R&D, QC, and pilot-scale applications. The system operates at vacuum levels down to ≤10 mbar when paired with a suitable diaphragm or oil-sealed vacuum pump, meeting requirements for low-boiling-point solvent recovery per USP and ICH Q5C guidelines. While the unit itself is not CE-marked or FDA-listed as a medical device, its construction materials (borosilicate 3.3 glass, PTFE, stainless steel 304) comply with ISO 8573-1 for clean compressed air systems and are suitable for GLP-compliant laboratories conducting method development and stability studies.
Software & Data Management
The RE-52CS-1 is a manually operated, analog-digital hybrid instrument with no embedded microprocessor or software interface. All operational parameters—including rotation speed, bath temperature (via external B-260 controller), and vacuum level (monitored externally)—are recorded manually or logged via external data acquisition systems. For audit-trail compliance in GMP environments, users integrate the unit into validated workflows using calibrated external sensors (e.g., digital vacuum gauges, PT100 bath probes) and electronic lab notebooks (ELNs) that support 21 CFR Part 11–compliant signature and version control. Documentation packages—including equipment qualification (IQ/OQ), preventive maintenance logs, and calibration certificates for ancillary devices—are maintained independently per laboratory SOPs.
Applications
- Solvent removal and sample concentration in natural product isolation and phytochemical extraction
- Removal of reaction solvents following Grignard, Suzuki, or esterification reactions in synthetic organic chemistry
- Concentration of protein solutions, enzyme preparations, and nucleic acid fractions prior to lyophilization or HPLC analysis
- Purification of heat-labile intermediates in pharmaceutical process development (API synthesis, impurity profiling)
- Recovery and recycling of high-purity solvents in fine chemical manufacturing to reduce waste disposal costs
- Preparative-scale dehydration of hygroscopic materials under inert atmosphere (with optional nitrogen inlet kit)
FAQ
What vacuum level is recommended for optimal performance with the RE-52CS-1?
For most common solvents (e.g., dichloromethane, ethyl acetate), a working vacuum of 10–50 mbar is typical; lower pressures (<10 mbar) may be used for high-boiling solvents but require careful temperature modulation to avoid bumping.
Is the RE-52CS-1 compatible with corrosive solvents such as concentrated HCl or HF?
No. The standard PTFE seals and borosilicate glass are incompatible with hydrofluoric acid and fuming mineral acids. Use only with organic solvents, aqueous buffers, and mild acids/bases (pH 2–12).
Can the RE-52CS-1 be operated under inert gas (e.g., nitrogen or argon)?
Yes—when equipped with an optional inert gas inlet valve and pressure-regulated supply, the system supports solvent evaporation under oxygen-free conditions for air-sensitive compounds.
What maintenance intervals are recommended for long-term reliability?
Inspect PTFE seals and ground-glass joints monthly; replace vacuum tubing every 6 months; calibrate external temperature and vacuum sensors annually per ISO/IEC 17025 protocols.
Does the RE-52CS-1 include a built-in chiller or cooling recirculator?
No. Cooling is provided externally via tap water or a recirculating chiller (recommended: −5 °C to 15 °C output, ≥10 L/min flow rate) connected to the condenser jacket inlets.
