Masterflex Ismatec P/S Series Peristaltic Pump System

Overview

The Masterflex Ismatec P/S Series Peristaltic Pump System is a precision-engineered, modular peristaltic pumping platform designed for reliable, pulse-free fluid transfer in laboratory, pilot-scale, and industrial process applications. Based on the proven principle of peristalsis—where rollers compress flexible tubing to create a sealed, moving occlusion—the system delivers accurate, contamination-free flow without valves, seals, or internal wetted parts beyond the tubing itself. This architecture ensures true fluid isolation, eliminates cross-contamination risk, and supports rapid changeover between chemically incompatible fluids. The P/S Series integrates a brushless DC motor drive with digital speed control and a range of interchangeable pump heads (e.g., IPC, IPC+), enabling scalable flow rates from 10 L/min depending on tubing size and rotational speed. Each system ships as a complete, factory-configured unit—including drive, pre-mounted pump head, and comprehensive documentation—optimized for immediate integration into analytical workflows, bioreactor feed lines, chromatography solvent delivery, and continuous sampling systems.

Key Features

• Modular design with plug-and-play pump heads compatible with Ismatec’s full IPC family (including high-pressure IPC+ and low-pulse IPC-LP variants)
• Digital speed control with 0.1 rpm resolution and ±0.2% speed accuracy across full 0.1–600 rpm range
• Open-collector remote I/O interface supporting motor start/stop, speed feedback (0–10 V or frequency output), local/remote mode selection, and alarm signaling—engineered for seamless PLC integration
• Non-isolated open-collector outputs require external current-limiting resistors and proper termination to ≤28 VDC sources (e.g., 24 V PLC inputs); relay interfacing supported via rear-panel 24 VDC supply (≤150 mA total)
• UL-recognized component construction per IEC/UL 61010-1 for safe operation in Class I, Division 2 hazardous locations when used with appropriate enclosures
• Intuitive front-panel keypad and dual-line LCD display with real-time rpm, direction, and status indicators
• Robust aluminum housing with IP20-rated enclosure suitable for controlled lab and cleanroom-adjacent environments

Sample Compatibility & Compliance

The P/S Series accommodates standard peristaltic tubing materials including PharMed BPT, Tygon® E-3603, Norprene®, and Viton®—each certified for USP Class VI, FDA 21 CFR 177.2600, and EU 10/2011 compliance where applicable. Tubing selection directly determines chemical resistance, pressure rating (up to 3 bar for IPC+ heads), and maximum flow capacity. All models meet CE marking requirements under the EMC Directive 2014/30/EU and Low Voltage Directive 2014/35/EU. The drive electronics are RoHS 2011/65/EU compliant and designed to support GLP/GMP data integrity requirements when paired with validated software solutions. While the pump itself does not include onboard audit trail or electronic signature functionality, its analog/digital I/O architecture enables full traceability when integrated with compliant SCADA or LIMS platforms adhering to FDA 21 CFR Part 11 guidelines.

Software & Data Management

The P/S Series operates as a standalone instrument with no proprietary software dependency; however, its standardized 0–10 V analog input/output and TTL-compatible pulse outputs allow direct connection to third-party control systems (e.g., LabVIEW, MATLAB, Siemens S7, Rockwell Logix). For advanced automation, optional Ismatec RS-232 or RS-485 communication modules (sold separately) enable ASCII command protocol integration, supporting remote parameter setting, real-time status polling, and event-triggered logging. When deployed in regulated environments, users may configure external data acquisition systems to record timestamps, speed setpoints, run duration, and alarm events—fulfilling ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) for audit readiness.

Applications

• Continuous reagent delivery in HPLC and UHPLC mobile phase systems
• Accurate media feeding and pH-adjustment dosing in mammalian and microbial bioreactors
• In-line sampling for online analyzers (e.g., NIR, conductivity, dissolved oxygen probes)
• Low-shear transfer of shear-sensitive biologics, cell suspensions, and polymer solutions
• Calibration fluid circulation in metrology labs and sensor validation rigs
• Environmental monitoring systems requiring long-term unattended operation with minimal maintenance

FAQ

What tubing sizes are supported by the P/S Series pump heads?
Standard IPC pump heads accept tubing inner diameters from 0.13 mm to 4.8 mm (e.g., Cole-Parmer #96400 series); IPC+ heads support up to 6.4 mm ID for higher flow applications. Always consult the Ismatec Tubing Selection Guide for pressure, flow, and chemical compatibility ratings.

Can the drive accept analog speed commands from a PLC?
Yes—the 0–10 V analog input accepts externally sourced speed references with 12-bit resolution. Input impedance is 100 kΩ; signal conditioning may be required for noisy industrial environments.

Is the 24 VDC supply on the rear panel isolated?
No—the 24 VDC output is referenced to the drive’s internal ground and is not galvanically isolated. It is intended only for low-power auxiliary devices such as indicator LEDs or small relays (≤30 mA each).

How often should tubing be replaced during continuous operation?
Lifespan depends on speed, pressure, tubing material, and fluid chemistry. Under typical lab conditions (300 rpm, aqueous solution, PharMed BPT 3.2 mm ID), expect 100–300 hours of service life. Monitoring flow rate drift >±3% is a recommended replacement trigger.