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Agilent 7890A-5975C GC-MS System (Refurbished)

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Brand Agilent Technologies
Origin USA
Model 7890A GC / 5975C MSD
Instrument Type Ion Trap Mass Spectrometer
Chromatography Type Conventional Gas Chromatography-Mass Spectrometry
Mass Range 1–1000 m/z
Resolution 1000–2000 (full width at half maximum, FWHM)
Sensitivity >300:1 signal-to-noise ratio (S/N) for methyl stearate at 1 pg on-column injection
Scan Speed 15,000 u/s

Overview

The Agilent 7890A-5975C GC-MS system is a fully integrated gas chromatography–mass spectrometry platform engineered for high-fidelity compound separation, identification, and quantitative analysis in regulated and research laboratories. This refurbished configuration combines the robust, temperature-stable 7890A gas chromatograph—with its advanced electronic pressure control (EPC), split/splitless injection, and programmable temperature vaporizing (PTV) compatibility—with the 5975C inert ion trap mass spectrometer. The system operates on electron ionization (EI) and optional chemical ionization (CI) modes, delivering structural elucidation through library-searchable fragmentation patterns and retention index correlation. Designed for routine environmental, pharmaceutical, forensic, and food safety applications, the platform supports method transfer across legacy and modern Agilent GC-MS workflows while maintaining full compliance with ISO/IEC 17025 and GLP documentation requirements.

Key Features

  • 7890A GC module featuring dual independent EPC channels, enabling precise carrier gas flow and pressure regulation across multiple columns and inlet configurations
  • 5975C MSD with high-capacity ion trap, optimized for enhanced sensitivity and dynamic range in both full-scan and selected ion monitoring (SIM) modes
  • Auto-tune capability with real-time mass calibration using perfluorotributylamine (PFTBA), ensuring consistent mass accuracy within ±0.1 u over extended operational periods
  • Integrated quadrupole mass filter and collision cell (in optional configurations) for tandem MS (MS/MS) experiments via ion isolation and resonant excitation
  • Front-panel touchscreen interface with embedded diagnostics, leak detection, and hardware status monitoring for rapid troubleshooting
  • Support for Agilent’s ChemStation software (G1701EA/EZ versions) with automated data acquisition, spectral deconvolution, and NIST library search integration

Sample Compatibility & Compliance

The system accommodates a broad range of volatile and semi-volatile organic compounds—including pesticides, PAHs, PCBs, residual solvents, and drug metabolites—across matrices such as water, soil extracts, biological fluids, and polymer leachates. Sample introduction options include standard split/splitless injectors, cold on-column (COC), and purge-and-trap (P&T) interfaces (with external accessories). All hardware components meet RoHS directives and UL/CSA safety standards. Data integrity features align with FDA 21 CFR Part 11 requirements when deployed with validated ChemStation configurations, including audit trail logging, electronic signatures, and user-access controls. Routine performance verification follows ASTM D5845 (for environmental analysis) and USP (for pharmaceutical residual solvent testing).

Software & Data Management

ChemStation G1701EA/EZ provides comprehensive instrument control, data acquisition, and post-run processing. It supports automated sequence generation, peak integration with baseline correction algorithms, and batch report generation compliant with LIMS export formats (e.g., CSV, XML, AIA). Raw data files (.D directories) are structured for long-term archival and reprocessing. Optional MassHunter Qualitative and Quantitative Analysis modules enable advanced spectral interpretation, isotopic pattern fitting, and multi-analyte calibration curve construction with weighting functions. All software installations undergo version-locking validation to ensure reproducibility in regulated environments subject to internal QA audits or external inspections.

Applications

  • Environmental monitoring: EPA Method 8270D (semi-volatile organics), 8260C (volatile organics), and 1613B (PCDD/Fs) analysis
  • Pharmaceutical QC: Residual solvent profiling per ICH Q3C guidelines and extractables/leachables screening in packaging materials
  • Food safety: Pesticide multiresidue analysis (EU SANTE/11813/2017), mycotoxin quantification, and flavor compound profiling
  • Forensic toxicology: Screening and confirmation of controlled substances and novel psychoactive substances (NPS) in blood and urine
  • Academic research: Reaction mechanism studies, metabolic pathway mapping, and natural product dereplication

FAQ

Is this system supplied with original Agilent factory calibration certificates?

Yes—each refurbished unit includes traceable calibration records for GC oven temperature, inlet pressure, detector response, and mass axis alignment, verified against NIST-traceable standards.
Can the 5975C ion trap be upgraded to support MS/MS functionality?

The base 5975C model supports MSn (n ≤ 3) in ion trap mode; MS/MS operation requires optional collision gas delivery hardware and firmware licensing, which can be retrofitted upon request.
What maintenance documentation is provided with the system?

A complete service history log, preventive maintenance checklist, and OEM-recommended consumables list (including column types, septa, liner specifications, and trap cleaning protocols) are delivered digitally and in hard copy.
Does the system support remote operation and networked data storage?

Yes—ChemStation supports LAN-based instrument control, shared method libraries, and centralized data archiving via Windows file shares or SMB-compatible NAS devices.
Are replacement parts and technical support available post-purchase?

Agilent-certified spare parts and application engineering support are accessible through authorized service partners globally, with documented SLAs for response time and turnaround.

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