Agilent 6890N GC coupled with 5975 Mass Selective Detector (Used, Refurbished)

Overview

The Agilent 6890N Gas Chromatograph coupled with the 5975 Mass Selective Detector (MSD) is a robust, benchtop GC–MS platform engineered for high-sensitivity trace organic analysis in regulated and research environments. This refurbished system operates on electron ionization (EI) and optional chemical ionization (CI) modes, delivering reproducible mass spectra across m/z 10–650 with unit mass resolution. The 6890N GC features precision pneumatic control, split/splitless injection, and oven temperature programming from 4 °C above ambient to 450 °C at rates up to 120 °C/min. The 5975 MSD incorporates an actively heated quadrupole mass filter, dual filament electron source, and high-vacuum turbomolecular pumping system (≥260 L/s for N₂), ensuring stable ion transmission and low baseline noise. As a legacy but widely validated platform, it remains fully compatible with modern Agilent ChemStation software (E.02.02 or later) and supports method transfer from newer GC–MS systems under GLP/GMP workflows.

Key Features

• Refurbished and functionally validated per Agilent-recommended maintenance protocols—including column oven calibration, detector sensitivity verification (using decafluorotriphenylphosphine, DFTPP), and vacuum integrity testing
• Integrated GC oven with precise temperature ramping and retention time locking (RTL) capability for inter-instrument method portability
• 5975 MSD equipped with auto-tune functionality, spectral library search (NIST/EPA/NIH), and real-time data acquisition at up to 10,000 amu/sec scan speed
• Support for multiple injection techniques: standard split/splitless, programmable temperature vaporizer (PTV), and cold-on-column (COC) via optional accessories
• Modular architecture enabling future upgrades—e.g., addition of a second detector (FID/ECD), auxiliary gas modules, or inert flow path components
• Compliance-ready configuration: audit trail enabled, electronic signatures supported, and data files structured in .D format compliant with FDA 21 CFR Part 11 requirements when used with validated ChemStation configurations

Sample Compatibility & Compliance

This GC–MS system accommodates volatile and semi-volatile organic compounds (VOCs/SVOCs) in matrices including water, soil extracts, biological fluids, polymers, and pharmaceutical excipients. It meets performance criteria outlined in U.S. EPA Methods 8260C (VOCs in solids/water) and 8270E (SVOCs), ASTM D3699 (hydrocarbon analysis in fuels), and ISO 11843-2 (detection limit estimation). All refurbished units undergo full system suitability testing per ICH Q2(R2) guidelines, including signal-to-noise ratio (>100:1 for chlorobenzene at 2 pg), retention time repeatability (<0.02 min RSD), and mass accuracy (<0.1 amu). Documentation includes Certificate of Reconditioning, IQ/OQ summary reports, and instrument-specific performance verification records.

Software & Data Management

Controlled exclusively via Agilent ChemStation (versions E.02.02.1444 and higher), the system supports both quantitative and qualitative workflows with customizable reporting templates, peak integration algorithms, and automated calibration curve generation. Raw data (.D folders) are stored in vendor-native format, preserving all acquisition metadata—including tune parameters, GC method settings, and detector voltage history—for retrospective reprocessing. Integration with LIMS is achievable through ODBC-compliant export functions or Agilent OpenLab CDS interfaces. Audit trail logs capture user actions, method modifications, and result approvals—essential for laboratories operating under GLP, ISO/IEC 17025, or pharmaceutical QA/QC frameworks.

Applications

• Environmental testing: pesticide residue screening in drinking water per EU Directive 98/83/EC; PAH quantification in sediment per ISO 18856
• Pharmaceutical impurity profiling and residual solvent analysis per ICH Q3C guidelines
• Food safety: mycotoxin detection (e.g., aflatoxins B₁/B₂/G₁/G₂) and flavor compound fingerprinting
• Forensic toxicology: confirmation of controlled substances in blood or urine using library match + retention index validation
• Polymer additive identification (e.g., antioxidants, plasticizers) via thermal desorption–GC–MS
• Academic research requiring cost-effective, high-fidelity mass spectral acquisition with established method libraries and peer-reviewed validation history

FAQ

Is this system supplied with original Agilent documentation and software licenses?
Yes—each unit includes a complete set of factory manuals, ChemStation installation media, and a legally transferable software license valid for activation on one workstation.
What refurbishment procedures are performed prior to delivery?
Full optical and electrical diagnostics, replacement of consumables (inlet liners, septa, gold seals, column nuts), quadrupole cleaning, source bake-out, vacuum system leak check, and multi-point sensitivity calibration using certified standards.
Can this GC–MS be integrated into an existing Agilent networked lab environment?
Yes—it supports LAN-based instrument control and data archiving via Agilent’s OpenLab Enterprise Edition when configured with appropriate server licensing.
Does the 6-month warranty cover labor, parts, and on-site service?
The warranty includes remote diagnostics, parts replacement, and one scheduled on-site service visit within the coverage period; extended service plans with annual PM are available upon request.
Are method transfer packages available for migration from newer Agilent GC–MS platforms?
Yes—Agilent provides backward-compatible method conversion tools, and our technical team delivers documented transfer protocols aligned with ASTM E2655 and ISO 17025 clause 7.2.2.