Hexion H/T20MM Benchtop High-Speed Centrifuge

Overview

The Hexion H/T20MM Benchtop High-Speed Centrifuge is an engineered solution for laboratories requiring reliable, high-RCF separation of biological, clinical, and industrial samples under controlled conditions. Operating on the principle of sedimentation force generation via rotational acceleration, this centrifuge delivers up to 24,640 × g at its maximum speed of 20,000 rpm—sufficient for pelleting subcellular organelles (e.g., mitochondria, lysosomes), clarifying bacterial cultures, concentrating viral particles, and isolating nucleic acids or exosomes. Its compact benchtop footprint (500 × 400 × 330 mm) integrates robust mechanical architecture—including a high-torque brushless DC motor, precision-machined aluminum rotor hub, and vibration-damped base—with regulatory-grade safety systems, making it suitable for routine QC/QA workflows in GLP-compliant environments and academic core facilities alike.

Key Features

• High-performance centrifugation: 20,000 rpm maximum speed with precise ±50 rpm speed control and real-time RCF calculation displayed directly on the TFT-LCD interface.
• Dual-mode operation: Touch-sensitive and physical keypads support intuitive parameter entry; dedicated RCF toggle key enables immediate unit switching without menu navigation.
• Biocontainment assurance: Airtight fixed-angle rotors equipped with RoHS 2015/863–compliant silicone elastomer sealing rings prevent aerosol escape during high-speed runs—critical for BSL-2 work involving pathogens or hazardous analytes.
• Adaptive power management: Wide-input voltage range (100–230 V, 50/60 Hz) ensures stable operation across global laboratory infrastructures, including regions with fluctuating grid supply.
• Vibration suppression system: Triple-stage mechanical damping—comprising tuned rubber mounts, dynamic counterbalance mass, and structural isolation between drive train and chassis—reduces operational noise to ≤60 dB(A) and prevents sample resuspension.
• Programmable workflow support: 20 user-defined protocols stored onboard; recall of last-used method at power-on; 10-step acceleration/deceleration ramping profiles for sensitive sample integrity preservation.

Sample Compatibility & Compliance

The H/T20MM accommodates diverse sample formats through 13 interchangeable fixed-angle rotors and optional polyamide fiber adapters. Compatible vessels include 0.2 mL PCR tubes, 1.5–2.0 mL microcentrifuge tubes, 15 mL and 50 mL conical tubes, 100 mL bottles, 96-well MTPs, PCR plates, and cell culture plates. All rotors are manufactured from aerospace-grade forged aluminum (T6 heat-treated) for fatigue resistance and dimensional stability at elevated rotational stress. The instrument holds CFDA registration and manufacturing authorization, and conforms to ISO 9001:2015 (quality management) and ISO 13485:2016 (medical device QMS). While not FDA 510(k)-cleared, its design supports alignment with USP , CLSI EP05-A3, and ISO 20943-1 validation frameworks for centrifuge performance qualification.

Software & Data Management

The embedded firmware provides full audit trail capability for critical parameters: run ID, date/time stamp, rotor ID, speed, RCF, duration, acceleration/deceleration profile, and fault logs. Though no external PC software is bundled, data export is supported via USB port (CSV format), enabling integration into LIMS or ELN platforms. The interface supports four language options—English, Chinese, Russian, and Portuguese—facilitating multilingual lab environments. All configuration changes during active runs (e.g., time extension, speed adjustment) are logged and do not require rotor deceleration, minimizing protocol interruption.

Applications

• Clinical diagnostics: Serum/plasma separation, PBMC isolation, urine sediment concentration.
• Molecular biology: Plasmid DNA purification, RNA extraction, protein precipitation, phage harvesting.
• Pharmaceutical development: Filtration aid removal, nanoparticle formulation clarification, excipient compatibility testing.
• Industrial microbiology: Yeast/bacterial biomass recovery, enzyme activity assay sample prep, fermentation broth processing.
• Academic research: Subcellular fractionation, vesicle isolation (exosomes, microvesicles), cryoprecipitate preparation.

FAQ

Is the H/T20MM compliant with FDA 21 CFR Part 11 requirements?
No—the system does not include electronic signature functionality or role-based access control as mandated by Part 11. However, its audit trail and immutable event logging meet foundational ALCOA+ principles for data integrity in non-GMP contexts.
Can this centrifuge be validated per IQ/OQ/PQ protocols?
Yes. Documentation packages—including mechanical specifications, calibration certificates for speed/RCF verification, and test reports for vibration and temperature stability—are available upon request to support installation qualification (IQ) and operational qualification (OQ).
What rotor certifications are provided with the standard configuration?
Each rotor carries individual serial-numbered traceability, material certification (ASTM B209 for aluminum alloy), and dynamic balancing report (ISO 1940 G2.5 grade). Biocontainment rotors include third-party leakage test documentation per EN 61010-2-020 Annex BB.
Does the unit support continuous operation beyond 24 hours?
The timer permits up to 99 h 59 min runtime; however, unattended extended operation is not recommended without thermal monitoring and scheduled maintenance per manufacturer guidelines.
Are replacement rotors and adapters supplied with CE marking?
Rotors intended for EU markets carry CE marking under Directive 2014/33/EU (Lifts) and 2014/35/EU (LVD), with Declaration of Conformity issued by TÜV Rheinland-accredited body. Non-EU configurations omit CE labeling but retain identical mechanical and safety specifications.