XTrust MASS-M01 Manual Solid-Phase Microextraction (SPME) Station

Overview

The XTrust MASS-M01 Manual Solid-Phase Microextraction (SPME) Station is a fully automated, multi-channel benchtop platform engineered for precise, reproducible, and solvent-minimized sample preparation in analytical laboratories. Unlike conventional liquid–liquid extraction or classical solid-phase extraction (SPE), the MASS-M01 implements the core principles of solid-phase microextraction — a headspace or direct-immersion equilibrium-based technique where analytes are selectively adsorbed onto a coated fused-silica fiber or membrane probe under controlled thermal and mechanical conditions. The system integrates programmable temperature-controlled sand bath heating (up to 340 °C), high-precision rotational agitation (0–1500 rpm), dual-solvent elution sequencing, and real-time parameter monitoring. Designed for compliance with modern green chemistry guidelines, it eliminates bulk organic solvent consumption while delivering quantitative recoveries suitable for GC, GC–MS, and HPLC–MS workflows. Its architecture reflects ISO/IEC 17025-aligned design rigor, supporting method validation and traceability in regulated environments.

Key Features

• Fully automated operation with pre-programmable extraction, desorption, and elution sequences — no manual fiber handling required during runtime.
• Multi-channel configuration supports parallel processing of two independent samples, enhancing throughput without cross-contamination risk.
• 316L stainless steel sand bath module ensures uniform thermal distribution, rapid heat-up kinetics, and chemical inertness against aggressive solvents and acidic/basic matrices.
• Dual-solvent elution capability enables gradient or sequential solvent switching — critical for recovering analytes with divergent polarities (e.g., VOCs and semi-volatile organics in a single run).
• Brushless DC motor delivers stable, low-vibration rotation up to 1500 rpm; intrinsically safe for use in environments requiring explosion-proof operation (ATEX Zone 2 compatible when installed per local electrical codes).
• High-resolution LCD interface displays real-time temperature (±0.5 °C accuracy), rotational speed (±1 rpm), and system status — all accessible via USB or RS-232 for integration into LIMS or ELN platforms.
• Integrated thermal safety logic: automatic shutdown at 420 °C surface temperature, audible/visual overheat alert when residual plate temperature exceeds 50 °C post-cycle.

Sample Compatibility & Compliance

The MASS-M01 accommodates standard 10–20 mL vials and custom containers up to 50 mL volume. Its column- and membrane-compatible probe interface accepts commercially available SPME fibers (e.g., PDMS, CAR/PDMS, DVB/CAR/PDMS) as well as proprietary membrane-based extraction devices. All wetted components comply with USP Class VI biocompatibility standards and FDA 21 CFR Part 11 requirements for electronic records and signatures when paired with validated software. Method documentation adheres to ASTM D7622 (standard practice for SPME of volatile organic compounds in water) and ISO 17931:2018 (determination of VOCs in soil using headspace SPME–GC–MS). The system supports GLP/GMP audit trails when operated with compliant data acquisition software.

Software & Data Management

The MASS-M01 communicates natively with XTrust SPME Control Suite (v3.2+), a Windows-based application enabling full method definition, parameter logging, and export of timestamped CSV reports. Audit trail functionality includes user login tracking, method versioning, and immutable event logs (start/stop times, temperature deviations, motor fault codes). Raw data files conform to ASTM E1381–20 standard for laboratory instrument data interchange. Optional OPC UA integration allows seamless connection to enterprise MES or SCADA systems in pharmaceutical or environmental testing facilities.

Applications

• Environmental analysis: Quantification of BTEX, PAHs, chlorinated hydrocarbons, and pesticides in aqueous, soil, and air samples per EPA Method 8260D and ISO 22037.
• Food & flavor chemistry: Headspace SPME-GC–MS profiling of esters, aldehydes, terpenes, and sulfur volatiles in beverages, dairy, and fermented products.
• Pharmaceutical QC: Residual solvent analysis (ICH Q3C) in APIs and excipients using static headspace SPME coupled to GC–FID.
• Forensic toxicology: Rapid screening of drugs of abuse (e.g., amphetamines, benzodiazepines) in blood and urine matrices with minimal sample prep.
• Industrial hygiene: Workplace air monitoring for VOC exposure assessment in accordance with NIOSH 2549 and OSHA PV2121.

FAQ

Is the MASS-M01 compatible with third-party SPME fibers and membranes?

Yes — the probe holder accepts standard 1-cm or 2-cm length fibers with 24-gauge or 25-gauge outer diameter, as well as flat-sheet polymeric membranes (up to 10 mm × 10 mm) mounted on stainless steel support frames.
Does the system support method validation per ICH guidelines?

Yes — all operational parameters (temperature ramp rate, agitation profile, equilibration time, desorption duration) are digitally logged and exportable for inclusion in validation protocols (ICH Q2(R2)).
Can the MASS-M01 be integrated into an automated sample introduction workflow?

Yes — the instrument features TTL-triggered output ports and ASCII command protocol support for synchronization with autosamplers, GC injectors, or robotic liquid handlers.
What maintenance is required for long-term reliability?

Annual calibration of temperature sensors and rotational encoder is recommended; sand bath media should be inspected quarterly for oxidation or particulate degradation. No lubrication or consumable motor parts are required due to brushless DC architecture.