Raykol AH-50 Automated Probe-Type Homogenizer
| Brand | Raykol |
|---|---|
| Origin | Fujian, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | AH-50 |
| Instrument Type | Probe-type Rotor-Stator Homogenizer |
| Dimensions (W×D×H) | 398 × 571 × 793 mm |
| Sample Capacity | 5–150 mL per tube |
| Throughput | Up to 36 samples per run |
| Pricing Range | USD 14,000 – 28,000 (FOB China) |
Overview
The Raykol AH-50 Automated Probe-Type Homogenizer is an engineered solution for high-throughput, reproducible sample homogenization in regulated analytical laboratories. It operates on the principle of rotor-stator mechanical shearing—where a rotating probe generates intense hydrodynamic forces within the sample matrix, disrupting cellular structures and ensuring uniform dispersion of analytes into extraction solvents. Designed specifically for preparatory workflows in food safety, pharmaceutical quality control, environmental monitoring, and life science research, the AH-50 replaces manual homogenization with programmable, walk-away automation. Its architecture integrates precise liquid dispensing, controlled probe immersion depth, variable-speed homogenization, and post-run probe cleaning—all synchronized under a single method-driven protocol. This eliminates operator-dependent variability, reduces exposure to hazardous organic solvents, and ensures compliance with Good Laboratory Practice (GLP) requirements for traceable, auditable sample preparation.
Key Features
- Full automation of solvent addition, homogenization, and probe rinsing—enabling unattended batch processing of up to 36 samples per cycle
- Programmable homogenization parameters including speed (rpm), duration (s), immersion depth (mm), and pause intervals—optimized per matrix type (e.g., muscle tissue, plant leaves, cream emulsions)
- Multi-stage cleaning protocol with configurable rinse solvents (e.g., water, acetone, methanol) and air-drying steps to minimize carryover between samples
- Intuitive graphical user interface with touch-screen operation; preloaded method templates aligned with pharmacopoeial and regulatory standards (e.g., USP <2341>, ISO 17025-compliant SOPs)
- Integrated safety interlocks: real-time motor temperature monitoring, positional error detection, over-torque protection, and automatic emergency stop upon lid opening or system fault
- Translucent front access door with LED illumination enables continuous visual verification of probe alignment, tube integrity, and homogenization progress without interrupting operation
Sample Compatibility & Compliance
The AH-50 accommodates standard conical-bottom centrifuge tubes (15 mL and 50 mL), as well as custom tube racks supporting 5–150 mL volumes—including polypropylene, glass, and screw-cap variants commonly used in HPLC, LC-MS/MS, and GC-MS workflows. It has been validated for use in methods referenced in major regulatory frameworks: Chinese Pharmacopoeia (ChP) 2015 Edition IV, General Chapter 2341 (Pesticide Residue Determination, Method V); ChP 2351 (Aflatoxin Assay); MOA Announcement No. 236 (Veterinary Drug Residues in Animal-Derived Foods); and national standards GB/T 22338-2008, GB 23200.20-2016, and NY/T 1379-2007. The system supports audit-ready documentation through timestamped log files and optional integration with LIMS via RS232 or Ethernet interfaces—facilitating adherence to FDA 21 CFR Part 11 requirements when paired with compliant electronic signature modules.
Software & Data Management
The AH-50 runs on embedded firmware with a dedicated method editor that allows users to define multi-step protocols—including sequential solvent addition, staggered homogenization cycles, and conditional cleaning logic. All executed methods are logged with metadata: date/time stamp, operator ID (optional login), sample position map, actual rpm and duration per tube, and fault event codes. Export formats include CSV and PDF reports compatible with laboratory information management systems (LIMS). Software updates are delivered via USB or network push, with version-controlled firmware archives maintained for internal validation and requalification purposes. Optional software packages support IQ/OQ documentation templates and electronic record archiving compliant with ISO/IEC 17025:2017 clause 7.5.2.
Applications
- Pharmaceuticals: Homogenization of herbal matrices (e.g., dried roots, powdered herbs), finished dosage forms (tablets, capsules), and biological tissues for residue analysis of mycotoxins, pesticides, or veterinary drugs
- Food & Agriculture: Processing of meat, fish, dairy, fruits, vegetables, and feed samples prior to LC-MS/MS quantification of nitroimidazoles, sulfonamides, quinolones, chloramphenicol, and avermectins
- Cosmetics: Emulsion disruption and active ingredient extraction from creams, lotions, and ointments for contaminant screening
- Environmental & Life Sciences: Tissue lysis of plant biomass, soil suspensions, and animal organs for metabolomic profiling or environmental toxin assessment
FAQ
What sample tube formats are supported?
Standard 15 mL and 50 mL conical centrifuge tubes (polypropylene or glass); custom racks available for alternative sizes (5–150 mL).
Does the AH-50 comply with GLP or GMP requirements?
Yes—when operated with enabled audit trail logging, user authentication, and method version control, it meets core GLP principles and supports GMP-aligned validation protocols.
Can the homogenization speed and time be adjusted per sample position?
No—speed and duration are set per method, but individual tube positions may be excluded from processing via software masking.
Is remote monitoring or control possible?
Local Ethernet or RS232 connectivity enables integration with lab networks; full remote control requires third-party middleware or custom API development.
What maintenance is required for long-term reliability?
Routine cleaning of probe shaft and drive coupling; annual calibration of dispensing accuracy and torque sensor verification recommended by Raykol Service Engineers.
