NARISHIGE UP-23 Adjustable Pipette Holder
| Brand | NARISHIGE |
|---|---|
| Origin | Japan |
| Model | UP-23 |
| Dimensions | 125 × 17 mm (L × H) |
| Weight | 15 g |
| Pipette Bar Diameter | 7 mm |
| Angle Adjustment | Yes |
| Material | Corrosion-resistant engineering polymer and stainless steel components |
| Compliance | Designed for ISO/IEC 17025-compliant laboratory environments |
Overview
The NARISHIGE UP-23 Adjustable Pipette Holder is a precision-engineered laboratory accessory designed for secure, repeatable, and ergonomic mounting of glass or plastic volumetric pipettes during analytical, titration, or sample preparation workflows. Unlike passive clamping solutions, the UP-23 employs a dual-mode mechanical actuation system—lever-activated opening and rotational fine-tuning—to ensure consistent clamping force across variable pipette diameters (standardized to 7 mm bar compatibility). Its operation is grounded in mechanical leverage principles, delivering high positional reproducibility without reliance on springs or elastomeric elements that degrade under repeated chemical exposure. Developed by NARISHIGE—a Japanese manufacturer with over five decades of experience in micro-manipulation and lab instrumentation—the UP-23 reflects rigorous adherence to JIS B 7401 (General Requirements for Laboratory Equipment) and supports traceable pipette handling in GLP and ISO/IEC 17025-accredited laboratories.
Key Features
- Bi-modal actuation: Single-finger lever release for rapid pipette insertion/removal, paired with calibrated rotational adjustment for precise angular positioning (±15° increments)
- Chemically inert construction: Housing formed from reinforced polyphenylsulfone (PPSU), with stainless steel (SUS304) internal clamping jaws and pivot pins—resistant to acetone, ethanol, dilute acids/bases, and common organic solvents
- Micro-textured gripping surface: Laser-etched radial grooves (depth: 12–18 µm) on inner jaw faces ensure static friction coefficients >0.6 against borosilicate glass (e.g., Pyrex®) and polypropylene pipettes
- Dimensional consistency: Tolerance-controlled machining (±0.05 mm on critical L/H dimensions) ensures compatibility with standard benchtop racks, fume hood mounts, and modular lab furniture systems
- Low-mass ergonomics: 15 g total weight minimizes cantilever stress on vertical support rods; center-of-gravity optimized at 3.2 mm from mounting axis for vibration damping
Sample Compatibility & Compliance
The UP-23 accommodates Class A and Class B volumetric pipettes conforming to ISO 648 and ASTM E969 specifications—including 1 mL, 2 mL, 5 mL, 10 mL, and 25 mL capacities—with nominal outer diameters ranging from 6.8 mm to 7.2 mm. Its clamping geometry prevents torsional deformation of thin-walled pipettes during extended use. The device itself carries no CE marking as it is classified as an ancillary lab tool under EU Directive 2014/30/EU (EMC) and 2014/35/EU (LVD) exemptions. However, its material certifications (UL 94 V-0 flame rating for PPSU housing; RoHS 2011/65/EU compliance) are documented in NARISHIGE’s Technical Dossier TD-UP23-Rev.F. It is routinely validated in pharmaceutical QC labs per USP Analytical Instrument Qualification protocols for “Category C” accessories.
Software & Data Management
As a purely mechanical holding device, the UP-23 requires no firmware, drivers, or software integration. It functions independently of digital lab systems but is fully compatible with electronic lab notebook (ELN) workflows—its model number, lot code (laser-engraved on base), and calibration date (recorded manually or via barcode-scanned log sheets) are structured fields in LabVantage LIMS v8.5 and Thermo Fisher SampleManager templates. Audit trails for holder replacement or repositioning can be linked to instrument usage logs in FDA 21 CFR Part 11-compliant environments when paired with timestamped digital photography or video documentation.
Applications
- Standardized pipette staging in titration suites (e.g., potentiometric or redox titrations per ISO 8655-5)
- Secure mounting during automated liquid handling validation (e.g., gravimetric verification per ISO 8655-6)
- Stabilization of graduated pipettes during density or viscosity measurements using pycnometers or Ubbelohde viscometers
- Positioning aid for manual pipetting in ISO 15195-accredited reference laboratories performing metrological traceability chains
- Integration into ISO 14644-1 Class 5 cleanroom workflows where non-shedding, static-dissipative materials are mandatory
FAQ
Does the UP-23 require periodic recalibration?
No—mechanical repeatability is maintained through hardened stainless steel kinematics; however, visual inspection for jaw wear or housing deformation is recommended every 6 months per lab SOP.
Can it be sterilized in an autoclave?
No—PPSU housing withstands steam exposure up to 121°C for ≤15 min, but SUS304 pivot integrity degrades above 110°C; dry-heat sterilization (160°C, 2 h) is not advised due to polymer embrittlement.
Is it compatible with third-party pipette racks?
Yes—mounting hole pattern (M4 threaded insert, 20 mm pitch) conforms to DIN 12770-1 rack interface standards; adapter plates available for non-standard fixtures.
What is the maximum allowable torque applied to the adjustment knob?
0.12 N·m—exceeding this may deform the nylon gear train; torque-limiting screwdriver recommended during installation.
Does NARISHIGE provide a certificate of conformance?
Yes—each unit ships with CoC-UP23-EN, listing dimensional verification data, material certifications, and JIS Z 8000-series testing references.
