H/T18MM High-Speed Centrifuge

Overview

The H/T18MM High-Speed Centrifuge is a benchtop, non-refrigerated centrifugal separation system engineered for routine and demanding applications in biomolecular research, clinical diagnostics, and quality control laboratories. It operates on the principle of sedimentation under high gravitational force (RCF), enabling rapid separation of cellular components, subcellular organelles, nucleic acids, proteins, and particulates from heterogeneous liquid samples. Designed for applications where temperature control is not critical—such as initial cell pellet harvesting, plasmid DNA precipitation, or polymerase chain reaction (PCR) product cleanup—the H/T18MM delivers reproducible performance at rotational speeds up to 18,500 rpm and maximum relative centrifugal forces of 23,610 × g. Its robust all-steel construction, stainless-steel rotor chamber, and integrated vibration-damping system ensure mechanical stability during extended operation, while the brushless frequency-controlled motor guarantees low-maintenance, quiet operation (<65 dB[A]) and precise speed regulation.

Key Features

• Brushless frequency-converter motor for stable speed control, extended service life, and minimal electromagnetic interference
• TFT true-color touch-screen interface displaying real-time setpoints and actual parameters (speed, RCF, time, remaining time)
• Dedicated RCF calculation key for immediate conversion between rpm and ×g values based on rotor radius
• Intelligent motor-driven door lock with audible and visual status feedback; meets IEC 61010-2-020 safety requirements for centrifuge enclosures
• Programmable memory supporting up to 20 user-defined protocols, including acceleration/deceleration profiles and hold-at-end functionality
• Multi-layer shock-absorption system incorporating silicone-damped feet and balanced rotor suspension to minimize transmission of operational vibration
• Full stainless-steel centrifuge chamber resistant to corrosion from common laboratory reagents (e.g., ethanol, chloroform, low-concentration acids/bases)

Sample Compatibility & Compliance

The H/T18MM accommodates a broad range of sample formats via interchangeable rotors—including fixed-angle rotors for high-RCF pelleting (e.g., 24 × 1.5/2.0 mL tubes, 6 × 50 mL conical tubes) and horizontal rotors for density-gradient separations (e.g., 12 × 10 mL tubes, dual 48-well microplate carriers). All rotors are certified for use within the device’s specified speed and load limits per ISO 15195:2019 (Clinical laboratory testing — Requirements for centrifuges). The unit complies with CE marking directives (2014/30/EU EMC Directive, 2014/35/EU LVD Directive) and conforms to GB/T 13722–2017 (Chinese national standard for centrifuge safety and performance). While not a refrigerated model, its thermal design ensures ambient-temperature operation remains within safe limits (≤40 °C surface temperature after 60 min continuous run at max speed), suitable for short-duration, high-speed spins common in nucleic acid and protein purification workflows.

Software & Data Management

The H/T18MM features embedded firmware with no external PC dependency. All operational data—including program ID, start/stop timestamps, final speed, RCF, elapsed time, and fault logs—are retained in non-volatile memory and accessible via the touch interface. Audit trail functionality records operator-initiated parameter changes, meeting basic GLP documentation needs. Although it does not support FDA 21 CFR Part 11-compliant electronic signatures or network connectivity, its 20-program storage capacity, password-protected parameter editing mode, and automatic error-code display (e.g., E01 = imbalance detection, E03 = lid interlock failure) facilitate traceable, repeatable use in regulated environments where manual logbook entries remain standard practice.

Applications

• Routine pelleting of mammalian and microbial cells (bacteria, yeast, cultured mammalian lines)
• Isolation of genomic DNA, plasmid DNA, and RNA using silica-membrane or alcohol-precipitation protocols
• Clarification of crude lysates prior to chromatography or electrophoresis
• Separation of serum/plasma from whole blood in clinical and veterinary labs
• Concentration of viral particles, exosomes, and extracellular vesicles (within RCF and time constraints of non-ultracentrifuge protocols)
• Preparative separation in food microbiology (e.g., pathogen enrichment from milk or juice matrices)
• Processing of agricultural extracts (e.g., plant pigment isolation, seed oil clarification)

FAQ

Is the H/T18MM suitable for use with infectious or biohazardous samples?

Yes—when equipped with sealed, biosafety-certified rotors and operated inside a certified biosafety cabinet or with appropriate PPE, provided all local institutional biosafety guidelines are followed.
Can I use this centrifuge for density gradient ultracentrifugation?

No—the H/T18MM is not an ultracentrifuge and lacks the vacuum chamber, rotor cooling, and RCF >100,000 × g required for sucrose/iodixanol gradient separations.
Does the unit include a rotor and adapters in the base configuration?

Yes—the standard delivery includes one fixed-angle 6 × 50 mL rotor and universal tube adapters for 15 mL and 50 mL conical tubes.
What maintenance is required beyond routine cleaning?

Annual verification of rotor balance, calibration of speed/RCF display against a certified tachometer, and inspection of door latch integrity are recommended per manufacturer guidelines.
Is rotor lifetime tracking supported?

No—rotor usage hours or spin cycles are not logged electronically; users must maintain manual records per ISO 20957-3:2020 recommendations for centrifuge rotor service life management.