Jiayuan CA30 Rat IVC Individually Ventilated Cage System
| Brand | Jiayuan |
|---|---|
| Origin | Beijing, China |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Domestic (China) |
| Model | CA30 (30-Cage Configuration) |
| Price | USD 6,300 (approx. ¥45,000) |
Overview
The Jiayuan CA30 Rat IVC Individually Ventilated Cage System is an engineered solution for maintaining Specific Pathogen-Free (SPF) housing conditions for laboratory rats in compliance with international animal welfare and biosafety standards. Based on the principle of positive-pressure, laminar-flow ventilation with individually regulated airflow per cage, the system isolates each animal microenvironment while ensuring uniform air distribution, controlled differential pressure gradients, and continuous HEPA-filtered air exchange. Designed for integration into conventional laboratory spaces—without requiring dedicated cleanrooms—the CA30 system delivers stable environmental control through static-pressure micro-airflow technology, minimizing turbulence and eliminating dead zones within cages. Its architecture supports GLP-compliant rodent studies, long-term breeding programs, and preclinical pharmacology research where consistent microbiological containment and physiological stability are critical.
Key Features
- Stainless steel 304 structural frame with electropolished surface finish, fully welded joints free of burrs or crevices—ensuring corrosion resistance, ease of decontamination, and mechanical stability.
- Individually adjustable airflow per cage via integrated damper valves and servo-controlled blower system; maintains uniform inter-cage differential pressure (20–50 Pa) across all 30 positions.
- Full-color LCD touchscreen interface with real-time monitoring of temperature, humidity, airflow rate, filter status, and system alarms—including power failure, HVAC fault, and environmental excursion alerts.
- Integrated timer-based HEPA filter replacement reminder and emergency “life window” activation protocol upon power loss to prevent hypoxia.
- Cage boxes fabricated from medical-grade PSU (polyphenylsulfone), offering optical clarity, autoclavability at 150°C/15 psi for 30 minutes, and chemical resistance to disinfectants including 75% ethanol, sodium hypochlorite, and peracetic acid.
- Sealing system utilizing high-purity silicone gaskets certified for repeated steam sterilization; cage-to-rack interface achieves leak-tight integrity verified per ISO 14644-1 Class 5 (≤100 particles ≥0.5 µm per cubic foot).
- Exterior-mounted PC water bottles with quick-connect fittings; stainless steel wire mesh lid (1Cr18Ni9, Ø1.8–4.0 mm) compliant with ASTM F2149-22 for structural load and airflow permeability.
Sample Compatibility & Compliance
The CA30 system accommodates standard rat housing configurations (470 × 312 × 260 mm cages) across five tiers (6 cages per tier). It meets national electrical safety standards (GB 4793.1–2019), conforms to ISO 55000 asset management principles for lifecycle maintenance, and supports audit readiness for AAALAC International accreditation. Environmental parameters—including air changes per hour (10–20 ACH), face velocity (≤0.18 m/s), noise emission (<55 dB[A] at 1 m), and settle plate microbial counts (<1 CFU/plate/4 h)—are validated per ISO 14698-1 and GB/T 16292–2010. The system’s sealed architecture enables operation in non-ISO classified rooms while sustaining intra-cage air quality equivalent to ISO Class 5.
Software & Data Management
The embedded controller logs timestamped operational data—including pressure differentials, temperature/humidity trends, filter runtime, and alarm events—for ≥30 days onboard. Data export is supported via USB 2.0 (CSV format) for integration into institutional LIMS or electronic lab notebooks. While the base system does not include 21 CFR Part 11-compliant user authentication or electronic signature modules, it provides configurable audit trail fields suitable for adaptation under GxP-aligned SOPs when deployed with supplementary IT governance controls.
Applications
- Longitudinal SPF rat studies requiring strict microbiological isolation and reproducible environmental baselines.
- Immunocompromised or transgenic rat models where cross-contamination risk must be minimized between genotypes or treatment groups.
- Toxicology and efficacy testing under OECD TG 407, 408, and 422 protocols where housing consistency directly impacts endpoint variability.
- Core facility shared-resource environments seeking scalable, low-footprint IVC infrastructure compatible with existing HVAC infrastructure.
- Regulatory submission support for IND/CTA dossiers where documented cage-level environmental control is required by EMA CHMP or NMPA guidelines.
FAQ
What is the maximum allowable ambient temperature range for stable CA30 operation?
The system is rated for ambient temperatures between 18–26°C and relative humidity 30–70% non-condensing. Performance validation assumes HVAC-stabilized room conditions.
Can the CA30 be integrated with centralized building management systems (BMS)?
Yes—via optional 4–20 mA analog output signals for pressure, temperature, and airflow; Modbus RTU communication is available as a factory-configurable upgrade.
Is the PSU cage material compatible with gamma irradiation sterilization?
No. PSU is validated for saturated steam sterilization only (150°C, 15 psi, 30 min). Gamma exposure may induce chain scission and reduce impact strength.
How frequently must HEPA filters be replaced under typical use?
Filter service intervals depend on particulate load but average 6–12 months; the built-in timer and pressure-drop monitoring provide objective replacement triggers.
Does the system meet ISO 14644-1 Class 5 requirements inside the cage?
Yes—when operated per specification (≥15 ACH, intact seals, validated filter integrity), intra-cage particle counts remain <100/ft³ for ≥0.5 µm particles, satisfying ISO Class 5 equivalency per GB/T 16292–2010.
