METTLER TOLEDO ME204 Analytical Balance
| Brand | METTLER TOLEDO |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic (China-manufactured) |
| Model | ME204 |
| Instrument Type | Analytical Balance |
| Maximum Capacity | 220 g |
| Readability | 0.1 mg |
| Repeatability | 0.1 mg |
| Linearity | ±0.2 mg |
| Internal Calibration | Yes |
| Pan Size | 90 mm diameter |
| Draft Shield Height | 220 mm |
| Dimensions (W×D×H) | 210 × 344 × 344 mm |
| Weight | Approx. 5.2 kg |
Overview
The METTLER TOLEDO ME204 Analytical Balance is an ISO/IEC 17025-aligned precision weighing instrument engineered for routine laboratory applications requiring high-resolution mass determination in the 0.1 mg readability range. Operating on electromagnetic force compensation (EMFC) principle, the ME204 delivers stable, drift-compensated measurements under variable ambient conditions—critical for quantitative analysis, formulation, and quality control workflows in pharmaceutical, chemical, academic, and materials testing laboratories. Its robust metal frame, integrated draft shield, and factory-optimized thermal design ensure long-term stability and minimal sensitivity to air currents or mechanical vibration. As a China-manufactured variant within METTLER TOLEDO’s globally harmonized ME series, the ME204 complies with international metrological requirements including OIML R76 and EN 45501, and supports traceable calibration through built-in internal reference weights.
Key Features
- Electromagnetic force compensation (EMFC) sensor technology ensuring high reproducibility and low drift over time
- One-touch internal calibration with automatic temperature-triggered recalibration (AutoCal™)
- Ergonomic front-access design with intuitive keypad and large backlit LCD display (128 × 64 pixels)
- Integrated draft shield with 220 mm effective height and removable glass panels for easy cleaning and sample access
- Adjustable front-leveling feet with bubble level indicator for rapid setup on non-ideal surfaces
- Stainless steel pan (90 mm Ø) mounted on a rigid aluminum base for mechanical stability and corrosion resistance
- RS232 interface standard; optional USB and Ethernet connectivity for data export and peripheral integration
- IP54-rated housing providing protection against dust ingress and accidental liquid splashes during routine handling
Sample Compatibility & Compliance
The ME204 accommodates standard laboratory samples including powders, granules, liquids in tared vessels, filter papers, and small solid components—within its 220 g maximum load and 90 mm pan diameter constraints. It meets essential regulatory expectations for analytical balance use in GLP, GMP, and ISO 9001 environments. While not pre-certified for FDA 21 CFR Part 11 compliance out-of-the-box, its data output architecture supports audit-trail-ready integration with compliant LIMS or ELN systems when paired with METTLER TOLEDO’s LabX software (sold separately). The balance conforms to ASTM E898–21 (Standard Guide for Selection and Use of Laboratory Balances), USP <41> (Balances), and ISO 17025 clause 6.4.3 regarding equipment suitability and verification.
Software & Data Management
The ME204 supports direct ASCII data transmission via RS232 to PCs or printers using standard protocols (e.g., SICS or MODBUS RTU). For advanced traceability, it is fully compatible with METTLER TOLEDO’s LabX standalone software, enabling automated result logging, user access control, electronic signatures, and full audit trail generation per FDA 21 CFR Part 11 requirements. Built-in application modes—including statistics, percent weighing, density determination, and formulation—can be accessed without external software. All calibration events, including date/time stamps and deviation values, are stored internally and retrievable via serial query.
Applications
- Quantitative preparation of standards and reference materials in QC labs
- Weighing active pharmaceutical ingredients (APIs) during tablet formulation development
- Gravimetric analysis in environmental testing (e.g., TSS, residue-on-ignition)
- Sample preparation for ICP-MS, HPLC, and GC-MS workflows requiring sub-milligram accuracy
- Educational laboratory instruction in analytical chemistry and metrology fundamentals
- In-process checks in fine chemical synthesis where batch consistency depends on precise reagent dosing
FAQ
What is the difference between readability and repeatability on the ME204?
Readability (0.1 mg) refers to the smallest displayed increment; repeatability (0.1 mg) is the standard deviation observed when repeatedly weighing the same load under identical conditions.
Does the ME204 support external calibration with certified weights?
Yes—the balance accepts manual external calibration using Class E2 or better weights, though internal calibration is recommended for daily verification.
Is the ME204 suitable for use in a fume hood?
Not recommended—draft shields are optimized for ambient lab conditions; operation inside a fume hood introduces airflow turbulence that compromises measurement stability.
How often should the ME204 be calibrated?
Internal calibration should be performed at power-on, after significant ambient temperature shifts (>2 °C), and before critical measurements; periodic verification with traceable standards is advised per ISO/IEC 17025 requirements.
Can the ME204 connect to a networked LIMS system?
Yes—via RS232-to-Ethernet gateways or directly using LabX software with TCP/IP configuration, enabling seamless bidirectional data exchange and electronic record retention.
