Bioer CHB-202 ThermoCell Precision Metal Block Heater
| Brand | Bioer |
|---|---|
| Model | CHB-202 |
| Temperature Range | −10 °C to 105 °C |
| Temperature Accuracy | ≤ ±0.5 °C |
| Heating Time to 100 °C | ≤ 35 min |
| Dimensions (L×W×H) | 300 × 200 × 160 mm |
| Net Weight | 3.2 kg |
| Power Supply | AC 220 V, 50 Hz, 120 W |
| Display | Full-color VFD |
| Programmable Setpoints | 5 independent temperature points with multi-segment continuous cycling capability |
| Standard Block Compatibility | A (40 × 1.5 mL), B (54 × 0.5 mL), C (96 × 0.2 mL), D (24 × φ15 mm), H (40 × 2.0 mL), G (26 × 0.5 mL + 24 × 1.5 mL), J (96-well microplate), E (water bath insert: 115 × 73 × 38 mm) |
| Timer Range | 1 min – 99 h 59 min |
Overview
The Bioer CHB-202 ThermoCell Precision Metal Block Heater is an actively cooled and heated dry block system engineered for reproducible thermal control in molecular biology, clinical diagnostics, and pharmaceutical quality control laboratories. Unlike water baths or air-based incubators, this device employs solid-state thermoelectric (Peltier) modules for both heating and cooling — enabling precise, contamination-free temperature regulation across a broad operational range from −10 °C to 105 °C. Its metal block architecture ensures rapid thermal equilibration, minimal gradient deviation across wells, and consistent heat transfer to sample tubes or plates without evaporation, condensation, or cross-contamination risks. Designed for routine use in GLP-compliant environments, the CHB-202 supports standardized protocols requiring strict thermal validation — including enzyme activation, DNA denaturation/annealing, cell lysis, reagent thawing, and stability testing of biologics.
Key Features
- Thermoelectric dual-mode operation: Integrated Peltier elements deliver stable cooling and heating without refrigerants or moving compressors — reducing maintenance and extending service life.
- High-resolution full-color VFD display: Simultaneously shows set temperature, real-time block temperature, elapsed time, remaining time, and active program segment.
- Multi-segment programmable control: Store up to five independent temperature setpoints; configure sequential ramps, holds, and cycles — ideal for complex thermal profiles such as PCR pre-incubation or stepwise protein refolding.
- Modular interchangeability: Tool-free block replacement within seconds; standard configurations accommodate common consumables (0.2–2.0 mL tubes, 96-well plates, 15 mm test tubes) — custom blocks available upon request for non-standard geometries.
- Calibration-ready architecture: Built-in offset adjustment function allows user-level temperature calibration against traceable reference probes per ISO/IEC 17025 requirements.
- Robust mechanical design: Aluminum alloy heating block with anodized surface finish ensures uniform conductivity, corrosion resistance, and long-term dimensional stability under repeated thermal cycling.
Sample Compatibility & Compliance
The CHB-202 accommodates a wide variety of primary labware through its interchangeable block system — supporting microcentrifuge tubes (0.2–2.0 mL), PCR strips, 96-well PCR plates, enzyme-linked immunosorbent assay (ELISA) plates, and larger diameter vessels up to φ15 mm. All standard blocks are manufactured to ISO 8573-1 purity class 5 tolerances and tested for thermal homogeneity (±0.3 °C max deviation at 37 °C across 96 positions). The instrument complies with IEC 61010-1:2010 for electrical safety in laboratory equipment and meets electromagnetic compatibility (EMC) requirements per EN 61326-1:2013. For regulated environments, audit trails, user access levels, and electronic signature support can be implemented via optional firmware upgrades aligned with FDA 21 CFR Part 11 and EU Annex 11 expectations.
Software & Data Management
While the CHB-202 operates autonomously via its front-panel interface, it includes an RS-232 serial port for external communication. Optional Bioer ThermoLink software enables remote parameter configuration, real-time temperature logging (up to 1 Hz sampling), export of CSV-formatted datasets, and generation of IQ/OQ documentation templates. All logged data include timestamps, operator ID (if authenticated), and environmental metadata — satisfying traceability requirements under ISO 15189 and CLIA guidelines. Firmware updates preserve historical calibration records and maintain backward compatibility with legacy method files.
Applications
- Molecular biology workflows: Enzyme restriction digestion, ligase reactions, cDNA synthesis, and plasmid miniprep elution steps requiring precise low-temperature incubation.
- Clinical diagnostics: Pre-analytical conditioning of serum, plasma, or CSF samples prior to immunoassay or nucleic acid extraction.
- Pharmaceutical QC: Accelerated stability studies at controlled sub-zero or elevated temperatures per ICH Q1A(R3) guidance.
- Cell culture support: Controlled warming of frozen vials, media pre-equilibration, and gentle thawing of sensitive primary cells.
- Industrial microbiology: Thermal inactivation validation, spore germination assays, and microbial growth rate profiling under defined thermal regimes.
FAQ
Does the CHB-202 support external temperature probes for chamber monitoring?
Yes — the unit features a dedicated input for optional PT100 or thermistor probes, enabling independent verification of block temperature against NIST-traceable standards.
Can the timer be disabled for continuous operation?
Yes — selecting “∞” in the timer menu disables automatic shutdown, allowing indefinite hold at the target temperature.
Is the device suitable for use inside a cold room?
It is rated for ambient operation between 5 °C and 35 °C; performance below 10 °C may extend cooling recovery time and affect minimum achievable temperature.
How often should temperature calibration be performed?
Per ISO/IEC 17025, calibration verification is recommended before each critical assay series or at least daily in high-throughput labs; full recalibration annually or after physical impact.
Are spare blocks and power cables available as accessories?
All standard and custom blocks, RS-232 cables, and international power cords (EU, UK, US, AU variants) are stocked and shipped globally with lead times under 5 business days.
