VITLAB Simplex2 Bottle Top Dispenser
| Brand | VITLAB |
|---|---|
| Origin | Germany |
| Model | Simplex2 |
| Type | Manual Bottle Top Dispenser |
| Volume Range | 0.2–100 mL |
| Minimum Graduation | 0.05 mL |
| Accuracy | ±0.5% |
| Precision (Repeatability) | ±0.1% |
| Sterilization | Autoclavable at 121 °C (after thorough cleaning) |
| Materials | PTFE, ETFE, PFA, FEP |
| Compliance | DIN EN ISO 8655-6, GLP-ready |
Overview
The VITLAB Simplex2 Bottle Top Dispenser is a precision-engineered manual liquid handling instrument designed for reliable, repeatable volumetric dispensing of reagents directly from standard laboratory bottles. Operating on a positive-displacement piston principle, the Simplex2 delivers consistent volume delivery across its full adjustable range—from 0.2 mL to 100 mL—without reliance on air displacement or complex electronics. Its robust all-fluoropolymer construction (PTFE, ETFE, PFA, and FEP) ensures chemical inertness against aggressive acids, bases, solvents, and oxidizing agents commonly encountered in analytical, quality control, and synthetic chemistry workflows. Designed and manufactured in Germany, the Simplex2 meets stringent European engineering standards and is validated for routine use in regulated environments where traceability, reproducibility, and material compatibility are critical.
Key Features
- Full autoclave compatibility at 121 °C — requires complete disassembly and cleaning prior to sterilization; all wetted parts retain dimensional stability and sealing integrity post-cycle.
- Integrated reflux valve prevents pre-dispense dripping and eliminates reagent waste during priming — ensuring zero loss before the first delivery stroke.
- Tool-free calibration in accordance with DIN EN ISO 8655-6 and Good Laboratory Practice (GLP) requirements; internal adjustment mechanism allows rapid verification and fine-tuning without external instrumentation.
- 360° rotatable discharge tube enables unobstructed label visibility during operation — supporting ergonomic bottle orientation and reducing workflow interruption.
- Universal neck interface: includes three polypropylene adapters for compatibility with common bottle thread sizes (e.g., GL45), plus direct mounting capability onto standard 45 mm threaded reagent containers.
- Modular design with replaceable seals and pistons — extends service life and supports cost-effective maintenance under ISO/IEC 17025-aligned lab asset management protocols.
Sample Compatibility & Compliance
The Simplex2 is suitable for dispensing aqueous solutions, organic solvents (including acetone, methanol, DMSO, and chlorinated hydrocarbons), concentrated mineral acids (HCl, HNO₃, H₂SO₄ up to fuming grades), caustic alkalis (NaOH, KOH ≤50 wt%), and peroxide-containing formulations. All fluid-contact surfaces comply with USP Class VI biocompatibility testing and EU Regulation (EC) No. 1935/2004 for food contact materials. Device documentation includes a factory-issued calibration certificate traceable to national metrology institutes (e.g., PTB, UKAS), satisfying audit requirements under ISO/IEC 17025, FDA 21 CFR Part 11 (when paired with compliant electronic log systems), and GMP/GLP frameworks.
Software & Data Management
As a fully manual mechanical dispenser, the Simplex2 does not incorporate embedded firmware or digital connectivity. However, its calibration procedure is fully documented and supports integration into paper-based or electronic laboratory notebooks (ELN) via standardized SOP templates. Each unit ships with a unique serial number and calibration record aligned with ISO 8655-6 Annex B reporting conventions — enabling seamless inclusion in instrument qualification protocols (IQ/OQ/PQ), equipment logs, and annual review cycles required by regulatory auditors.
Applications
- Preparation of calibration standards and reference solutions in environmental testing labs (e.g., EPA Method 200.7, ISO 17294-2).
- Accurate dispensing of titrants and indicators in volumetric analysis workflows compliant with ASTM E200 and ISO 3696.
- Reagent distribution in pharmaceutical QC laboratories performing assays per USP and Ph. Eur. 2.2.47.
- Controlled addition of catalysts or hazardous precursors in synthetic organic chemistry, minimizing operator exposure through closed-bottle operation.
- Supporting ISO/IEC 17025 accredited testing where documented uncertainty budgets require verified volumetric performance at defined confidence intervals (k = 2).
FAQ
Is the Simplex2 compatible with hydrofluoric acid (HF)?
Yes — all fluoropolymer components (PFA, FEP, ETFE) resist HF corrosion up to 48 wt% at ambient temperature; however, extended exposure above 60 °C is not recommended.
Can the dispenser be calibrated in-house without third-party certification?
Yes — per DIN EN ISO 8655-6 Clause 7.3, users may perform functional verification and adjustment using certified Class A glassware and gravimetric methods; formal calibration certificates require accredited providers.
What is the maximum operating pressure the device can withstand?
The Simplex2 is not rated for pressurized dispensing; it operates exclusively under atmospheric or slight vacuum conditions typical of standard reagent bottle storage.
Does the device meet FDA requirements for use in drug manufacturing?
While the Simplex2 itself is not FDA-listed, its materials compliance, calibration traceability, and GLP-aligned design support its use in cGMP environments when included in validated process workflows and maintained per written procedures.
How often should recalibration be performed?
Annual calibration is recommended for routine use; more frequent verification (e.g., quarterly) is advised when handling high-value standards, critical assay reagents, or following equipment impact or sterilization events.
