Eppendorf Research Plus Single-Channel Manual Pipette, 100–1000 µL

Overview

The Eppendorf Research Plus Single-Channel Manual Pipette (100–1000 µL) is a precision-engineered liquid handling instrument designed for high-reproducibility volumetric transfer in research, quality control, and clinical laboratories. Based on Eppendorf’s patented spring-loaded piston mechanism and air displacement principle, the pipette delivers consistent aspiration and dispensing across its full range through optimized internal air cushion dynamics and low-friction sealing components. Its ergonomic design—featuring a lightweight body (approx. 95 g), low plunger activation force (<1.5 N at full volume), and adjustable tip ejection force—reduces operator fatigue during extended use while maintaining strict adherence to ISO 8655 standards for accuracy and precision. Manufactured in Hamburg, Germany, each unit undergoes individual factory calibration and traceable certification, ensuring compliance with international metrological requirements for analytical workflows.

Key Features

• ISO 8655-compliant performance: Accuracy ±3.0 µL (±0.3% of nominal volume) and precision ≤1.5% CV at 1000 µL, validated per ISO 8655-2 and -5
• Ergonomic operation: Soft-touch pipetting action, adjustable tip ejection pressure, and forward/reverse volume adjustment dial for intuitive setting
• Chemical resistance: Fully autoclavable upper body (121 °C, 20 min, 1 bar); corrosion-resistant anodized aluminum housing and PTFE-sealed piston
• Volume locking system: Integrated lock prevents accidental volume changes during transport or storage
• Tip compatibility: Optimized for universal fit with standard conical tips (including Eppendorf PhysioTips and certified third-party alternatives)
• Traceability: Each pipette carries a unique serial number and includes a factory calibration certificate compliant with ISO/IEC 17025-accredited practices

Sample Compatibility & Compliance

The Research Plus 100–1000 µL pipette is suitable for aqueous solutions, buffers, cell suspensions, serum, and low-viscosity organic solvents (e.g., ethanol, acetone, DMSO). It is not recommended for highly viscous, volatile, or corrosive liquids (e.g., concentrated acids, bases, or halogenated solvents) without appropriate tip selection or technique adaptation. The device meets essential regulatory expectations for laboratory instrumentation under Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) frameworks. Its calibration documentation supports audit readiness for FDA 21 CFR Part 11–aligned environments when used with Eppendorf’s optional calibration management software (e.g., Eppendorf CalCheck). All units are CE-marked and conform to IEC 61010-1 for electrical safety and EN 61326-1 for electromagnetic compatibility.

Software & Data Management

While the manual Research Plus model operates independently of software, it integrates seamlessly into digital lab ecosystems via Eppendorf’s calibration and service infrastructure. Users may register devices in Eppendorf’s online portal to access electronic calibration certificates, service history logs, and scheduled maintenance alerts. For labs requiring full audit trails, the pipette can be paired with Eppendorf CalCheck software (sold separately), which enables digital recording of calibration events, user authentication, electronic signatures, and exportable PDF reports compliant with ISO/IEC 17025 and ALCOA+ data integrity principles. Routine verification checks (e.g., gravimetric testing per ISO 8655-6) can be documented using standardized templates aligned with internal SOPs and external accreditation bodies such as A2LA or UKAS.

Applications

This pipette serves critical roles in molecular biology (PCR setup, restriction digests, plasmid dilutions), cell culture (media supplementation, reagent addition), pharmaceutical QC (standard solution preparation, assay plate filling), and environmental testing (extraction solvent dosing, sample aliquoting). Its stability across temperature gradients (15–30 °C operating range) and resistance to humidity-induced drift make it particularly suited for multi-step protocols requiring repeated transfers over time. In regulated environments—including clinical diagnostics labs accredited to CLIA or ISO 15189—the Research Plus supports method validation studies where volumetric uncertainty budgets must account for instrument contribution, typically contributing <0.2% relative uncertainty at 1000 µL under controlled conditions.

FAQ

Is this pipette supplied with calibration documentation?
Yes—each unit ships with a factory-issued calibration certificate traceable to national standards (PTB, Germany), including measured values at 10%, 50%, and 100% of nominal volume.
Can it be autoclaved?
The upper body (piston assembly and housing) is fully autoclavable at 121 °C for 20 minutes; the lower sleeve and tip cone require separate cleaning and should not be autoclaved.
What is the recommended recalibration interval?
Eppendorf recommends annual calibration for routine use; more frequent verification (e.g., quarterly) is advised in high-throughput or GxP-regulated settings.
Does it support electronic data capture?
Not natively—but when registered and managed via Eppendorf CalCheck or integrated into LIMS via CSV report export, full digital traceability is achievable.
Are replacement parts available globally?
Yes—seals, springs, tip cones, and complete repair kits are distributed through Eppendorf’s authorized service network in over 120 countries, with typical lead time of 3–5 business days.