VWR Advanced 3750 Reciprocating Shaker
| Origin | China |
|---|---|
| Manufacturer Type | Distributor |
| Product Category | Domestic |
| Model | 89032-098 |
| Price | Upon Request |
Overview
The VWR® Advanced 3750 Reciprocating Shaker is an engineered platform for precise, reproducible orbital motion in life science and bioprocessing laboratories. Unlike generic shakers, it employs a single-eccentric drive mechanism coupled with a brushless DC motor to deliver consistent linear reciprocation—ideal for suspension cultures, microbial growth, solubility studies, and reagent mixing where uniform shear and minimal vortexing are critical. Its microprocessor-controlled feedback loop continuously monitors actual shaking speed via integrated tachometric sensing and dynamically adjusts motor output to maintain setpoint accuracy within ±1% across variable load conditions—ensuring compliance with method-critical protocols such as ASTM D4097 (for suspension homogeneity) or USP environmental monitoring workflows. Designed for integration into controlled environments, the unit operates reliably within CO₂ incubators, cold rooms, and humidity-controlled chambers across a temperature range of –10 °C to 60 °C (14 °F to 140 °F), making it suitable for long-term cell culture maintenance under physiological gas conditions.
Key Features
- Microprocessor-based closed-loop speed control with real-time RPM verification and automatic correction under dynamic load shifts
- Single-eccentric drive architecture with permanently lubricated ball bearings and maintenance-free brushless DC motor for continuous-duty operation
- Independent dual LED displays showing simultaneously set speed (rpm) and elapsed/remaining time—visible up to 2 meters across standard lab benches
- Ramp-to-set function minimizing liquid splashing during startup; programmable acceleration profiles support sensitive suspension cultures
- Integrated load sensor that detects tray imbalance and automatically reduces speed to a safe threshold—preventing sample loss and mechanical stress
- Spill-resistant chassis design with internal fluid channeling pathways to divert condensate or accidental spills away from electronics and motor housing
- RS-232 serial interface enabling bidirectional communication for remote parameter setting, data logging, and audit-trail generation compatible with GLP/GMP environments
Sample Compatibility & Compliance
The Advanced 3750 accommodates standard platforms including 300 × 300 mm trays, universal clamping systems for flasks (50–5000 mL), deep-well plates, and custom fixtures. Its structural rigidity and low-vibration footprint ensure compatibility with optical density readers and automated liquid handlers when placed on shared benchtops. The device conforms to IEC 61010-1:2010 for laboratory equipment safety and meets electromagnetic compatibility requirements per EN 61326-1. While not certified as a medical device, its operational repeatability supports adherence to ISO/IEC 17025 quality management systems when used in accredited testing labs. For regulated biomanufacturing, the RS-232 interface facilitates integration into FDA 21 CFR Part 11-compliant data acquisition systems when paired with validated software.
Software & Data Management
No proprietary software is bundled; however, the RS-232 port supports ASCII-based command protocols compatible with LabVIEW™, Python (pySerial), and MATLAB® for custom script-driven control and timestamped RPM/time logging. The onboard memory retains last-used parameters—including speed, duration, ramp rate, and alarm mute status—even after power interruption, eliminating manual reconfiguration between runs. Audit-ready logs can be exported to CSV format for traceability in QA/QC documentation. Speed calibration mode allows end-user verification and adjustment using an external tachometer—supporting routine instrument qualification per IQ/OQ protocols.
Applications
- Adherent and suspension mammalian cell culture in T-flasks and roller bottles under CO₂-enriched atmospheres
- Microbial fermentation kinetics studies requiring constant agitation without foaming or shear-induced lysis
- Antibiotic susceptibility testing (AST) plate agitation prior to reading on automated MIC analyzers
- Solubility profiling of APIs in simulated gastric/intestinal fluids per USP dissolution apparatus guidelines
- Immunoprecipitation wash steps and ELISA plate mixing where uniform lateral motion improves binding efficiency
- Environmental microbiology—shaking of water samples for heterotrophic plate count (HPC) enrichment per Standard Methods 9215B
FAQ
Can this shaker operate inside a CO₂ incubator at 5% CO₂ and 37°C?
Yes—the unit is rated for continuous operation in CO₂-rich, humidified environments up to 60°C, provided ambient condensation is managed per manufacturer’s venting recommendations.
Is speed calibration traceable to NIST standards?
The built-in calibration mode enables user verification against an externally calibrated tachometer; full NIST-traceable calibration requires third-party service with documented uncertainty budgets.
Does the timer support countdown with auto-shutdown and audible alert?
Yes—programmable countdown mode triggers both visual indicator change and configurable audible alarm upon completion; mute function is accessible via touchpad.
What safety certifications does the unit carry?
It complies with IEC 61010-1:2010 (Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use) and EN 61326-1:2013 (EMC for Laboratory Equipment).
Can multiple units be daisy-chained via RS-232 for centralized control?
No—RS-232 is point-to-point only; multi-unit coordination requires a serial server or USB-to-serial hub with individual address assignment in host software.
