IKA T50 Digital ULTRA-TURRAX Homogenizer

Overview

The IKA T50 Digital ULTRA-TURRAX Homogenizer is a high-performance, benchtop rotor-stator homogenizer engineered for reproducible mechanical dispersion, emulsification, and cell disruption across research, quality control, and pilot-scale laboratory environments. Based on the well-established Couette flow principle, the T50 generates intense shear forces through precise relative motion between a rapidly rotating rotor and a fixed stator—enabling efficient particle size reduction, suspension homogenization, and uniform phase mixing in viscous and non-Newtonian media. Designed and manufactured in Staufen, Germany, the instrument integrates a robust triple-bearing drive system, thermally stable motor architecture, and real-time torque-responsive speed regulation to maintain consistent rotational velocity despite dynamic viscosity changes during processing. Its compact footprint, IP21-rated enclosure, and integrated electronic safety circuit ensure operational reliability under routine laboratory conditions compliant with DIN EN 60529 environmental protection standards.

Key Features

• Triple-bearing drive shaft for enhanced mechanical stability, reduced vibration, and extended service life under continuous operation
• Infinitely variable speed control (4,000–10,000 rpm) with analog tachometer display and ±1% speed stability—even under load-induced viscosity fluctuations
• Integrated electronic soft-start circuit ensures smooth, jerk-free acceleration and eliminates mechanical stress on both drive train and sample container
• Modular dispersion tool interface: quick-insertion design allows tool-free exchange of standardized ULTRA-TURRAX dispersing elements (e.g., S50N-G45, S50N-G25, S50N-G19)
• Dual-mode functionality: when equipped with optional R50 anchor stirrer, the unit operates as a high-shear overhead stirrer for macro-mixing applications
• Tachometer output socket enables external speed monitoring or integration into automated data logging systems
• Thermal overload protection and automatic load cut-off safeguard motor integrity during prolonged or high-viscosity operation

Sample Compatibility & Compliance

The T50 accommodates aqueous and non-aqueous samples ranging from low-viscosity buffers (≥0.25 L) to highly viscous suspensions (up to 5,000 mPa·s) within volumes up to 30 L—provided appropriate vessel geometry, cooling, and support fixtures (e.g., R2722/R2723 stands, RH5 clamps) are used. All wetted parts—including stainless steel rotors, stators, and shafts—comply with ISO 8507 and FDA-recommended materials for laboratory equipment. The device meets CE marking requirements under the EU Machinery Directive 2006/42/EC and Electromagnetic Compatibility Directive 2014/30/EU. Its analog speed interface and absence of embedded software render it inherently compatible with GLP/GMP workflows requiring minimal validation burden; however, when paired with DZM Control o tachometer or third-party SCADA systems, audit-trail-capable data capture may be implemented per 21 CFR Part 11 guidelines using external recording hardware.

Software & Data Management

The IKA T50 operates as a standalone electromechanical instrument without onboard digital firmware or proprietary software dependency. Speed is monitored via analog scale readout and optionally validated using external tachometric devices such as the DZM Control o. For laboratories requiring traceable process records, the tachometer output signal (0–10 V DC proportional to rpm) can be routed to programmable logic controllers (PLCs), data acquisition modules (e.g., NI USB-6009), or LIMS-integrated analog input cards. This architecture supports fully documented batch records—including time-stamped speed profiles, run duration, and operator ID—when deployed alongside validated external instrumentation meeting ALCOA+ data integrity principles.

Applications

• Cell lysis and subcellular fractionation in molecular biology workflows
• Preparation of stable oil-in-water and water-in-oil emulsions for pharmaceutical formulation development
• Homogenization of polymer dispersions, pigment suspensions, and ceramic slurries prior to rheological or particle size analysis
• Disintegration of tissue samples for histopathology or proteomic extraction protocols
• High-shear blending of adhesives, sealants, and composite matrix precursors in materials science labs
• QC testing of viscosity-dependent product consistency across food, cosmetic, and agrochemical manufacturing

FAQ

Is the T50 suitable for sterile processing?
The T50 itself is not autoclavable; however, all ULTRA-TURRAX dispersing tools (e.g., S50N-G series) are constructed from AISI 316 stainless steel and may be sterilized via dry heat (180 °C, 2 h), ethylene oxide, or gamma irradiation—subject to validation per ISO 11135 or ISO 11137.
Can the T50 be used with corrosive solvents?
Standard dispersing elements resist mild organic solvents and aqueous media; for aggressive chemicals (e.g., concentrated acids, halogenated hydrocarbons), consult IKA’s chemical compatibility chart and consider PTFE-coated or Hastelloy variants where available.
What maintenance intervals are recommended?
IKA recommends inspection of bearing play and shaft runout every 500 operating hours; lubrication is factory-sealed and non-serviceable. Routine cleaning of stator slots and rotor grooves with non-abrasive tools is advised after each use.
Does the T50 support regulatory-compliant electronic signatures?
No—the unit lacks embedded software or user authentication. Electronic signatures must be applied at the data acquisition layer (e.g., via validated LabArchives or DeltaV systems receiving its analog tachometer output).