RO Membrane Cartridge for MilliporeSigma IQ 7003, RiOs 3/5, and Elix 3 Systems
| Brand | Deepflow |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | PRC |
| Model | CYRC35HA1 |
| Pricing | Available Upon Request |
Overview
The CYRC35HA1 RO membrane cartridge is a certified replacement component engineered for seamless integration with MilliporeSigma’s IQ 7003, RiOs 3, RiOs 5, and Elix 3 ultra-pure water purification systems. Designed to deliver consistent rejection of dissolved ions, organic contaminants, colloids, and microorganisms, this spiral-wound polyamide thin-film composite (TFC) membrane operates on the principle of cross-flow reverse osmosis—applying hydraulic pressure exceeding the osmotic threshold to drive purified water (permeate) through the semi-permeable membrane while retaining >99% of total dissolved solids (TDS), silica, endotoxins, and particulates ≥0.0001 µm in effective size. Its performance is validated under standard feed conditions of 25°C, 200 ppm NaCl, 150 psi (10.3 bar), and pH 6.5–7.5, aligning with ISO 3696 Grade 1 and ASTM D1193 Type I water specifications when used within a fully commissioned multi-stage purification architecture.
Key Features
- Spiral-wound TFC membrane element with standardized 10-inch (254 mm) length and 2.5-inch (63.5 mm) diameter housing—compatible with OEM-designed RO chambers in IQ 7003, RiOs 3/5, and Elix 3 platforms.
- Optimized flux density (≥12 L/m²·h at standard test conditions) balanced against long-term fouling resistance, supporting stable operation across variable municipal feed water qualities (TDS 50–500 ppm).
- Chemically resistant polyamide active layer tolerant of low-concentration sodium hypochlorite (≤5 ppm) for periodic sanitization and compatible with standard RO cleaning formulations (pH 2–12).
- Pre-assembled, pre-rinsed, and individually sealed in sterile-grade polyethylene packaging—minimizing installation-induced contamination risk and eliminating pre-use flushing requirements.
- Traceable lot numbering and batch-specific performance documentation provided per unit, supporting GLP-compliant maintenance logs and preventive service scheduling.
Sample Compatibility & Compliance
The CYRC35HA1 is intended exclusively for use in laboratory-scale point-of-use (POU) and centralized ultra-pure water generation systems where source water meets ANSI/NSF Standard 58 pre-treatment recommendations (e.g., sediment filtration, carbon adsorption, and softening as needed). It is not rated for direct connection to raw well or surface water without upstream conditioning. The cartridge complies with RoHS Directive 2011/65/EU for hazardous substance restrictions and conforms to ISO 9001:2015 manufacturing controls. While not an FDA-listed medical device, its material composition (FDA-compliant polypropylene housing, USP Class VI–certified elastomers) supports use in pharmaceutical QC laboratories operating under cGMP Annex 1 and EU GMP Chapter 4 water system validation protocols.
Software & Data Management
As a passive consumable component, the CYRC35HA1 does not interface with system firmware or onboard controllers. However, its usage lifecycle is tracked via the host platform’s built-in maintenance scheduler (e.g., IQ 7003’s Service Counter or Elix 3’s Cartridge Life Monitor). Replacement events are automatically logged with timestamps and operator ID (where authenticated login is enabled), generating audit-ready records compatible with 21 CFR Part 11–compliant electronic data capture when integrated with MilliporeSigma’s LabManager or third-party LIMS via Modbus TCP or OPC UA gateways. Batch certificates of conformance include nominal rejection rate, pressure drop tolerance (<0.5 bar at rated flow), and integrity test pass/fail status.
Applications
- Feed water pretreatment stage in multi-barrier ultra-pure water systems serving analytical instrumentation (HPLC, IC, LC-MS, ICP-MS) requiring resistivity ≥18.2 MΩ·cm and TOC <5 ppb.
- Production of ASTM Type I reagent water for cell culture media preparation, molecular biology assays (PCR, qRT-PCR), and ELISA buffer formulation.
- Supporting ISO/IEC 17025-accredited testing labs where documented traceability of purification consumables is mandated for method validation (e.g., ISO 15195, CLSI EP21-A).
- Ongoing compliance with pharmacopeial water quality requirements—including USP , Ph. Eur. 2.2.44, and JP 17 General Chapter “Purified Water” and “Water for Injection” specifications.
FAQ
What is the recommended replacement interval for the CYRC35HA1 cartridge?
Typical service life ranges from 6 to 12 months depending on feed water quality, daily throughput, and pre-treatment efficacy. Systems equipped with real-time conductivity monitoring and pressure differential sensors will trigger alerts when normalized permeate flow declines by ≥15% or salt passage increases by ≥10% relative to baseline.
Can this cartridge be used in non-MilliporeSigma systems with identical physical dimensions?
Mechanical fit does not guarantee functional compatibility. Flow path geometry, O-ring placement, and pressure rating tolerances are system-specific; unauthorized substitution may void OEM warranty and compromise water quality certification.
Is sterilization required before installation?
No. Each unit undergoes gamma irradiation (25 kGy) during final packaging and is supplied ready-to-install. Post-installation system sanitization (e.g., hot water or ozone) must follow the host platform’s validated protocol.
Does Deepflow provide technical support for system integration issues?
Yes—Deepflow maintains a dedicated applications engineering team with cross-platform expertise in MilliporeSigma, ELGA, and Veolia water systems. Support includes installation verification checklists, pressure-drop diagnostics, and troubleshooting guides aligned with ISO 21649:2020 water system commissioning standards.
