Titan HDC-18KL Plus Desktop High-Speed Centrifuge (Rotors Sold Separately)
| Brand | Titan |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | HDC-18KL Plus |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | 10,000–30,000 rpm (Max. 18,000 rpm) |
| RCF Max | 24,100 × g |
| Max Capacity | 4 × 250 mL |
| Rotor Configuration | Fixed-Angle Rotor Compatible |
| Dimensions (W×D×H) | 450 × 550 × 340 mm |
| Power Supply | 220 V, 50/60 Hz |
Overview
The Titan HDC-18KL Plus is a high-performance benchtop high-speed centrifuge engineered for routine and advanced separation tasks in life science, clinical diagnostics, and industrial R&D laboratories. Operating on the principle of sedimentation under controlled rotational acceleration, it delivers precise, reproducible separation of biological suspensions, cell lysates, subcellular organelles, nanoparticles, and viscous process samples. With a maximum speed of 18,000 rpm and a peak relative centrifugal force (RCF) of 24,100 × g, the HDC-18KL Plus bridges the performance gap between standard benchtop units and floor-standing ultracentrifuges—enabling rapid pelleting of mammalian cells, bacterial cultures, exosomes, and precipitated proteins without requiring vacuum or refrigerated infrastructure.
Key Features
- Robust brushless DC motor with electronic speed control ensures stable rotational output across the full speed range (300–18,000 rpm) with ±10 rpm speed accuracy at setpoint.
- Intelligent rotor recognition interface supports plug-and-play compatibility with a range of optional fixed-angle rotors—including 4 × 250 mL, 6 × 100 mL, and 12 × 15 mL configurations—each validated for mechanical integrity and balanced load distribution.
- Microprocessor-controlled acceleration/deceleration profiles minimize sample heating and shear stress; programmable soft-braking prevents resuspension of delicate pellets.
- Double-layer reinforced stainless-steel chamber with integrated safety interlock system meets IEC 61010-2-020 requirements for centrifuge-specific electrical and mechanical safety.
- Real-time digital display shows actual speed (rpm), RCF (×g), elapsed time, remaining time, and temperature (when equipped with optional cooling module).
- Compact footprint (450 × 550 × 340 mm) enables installation on standard laboratory benches without dedicated floor space or structural reinforcement.
Sample Compatibility & Compliance
The HDC-18KL Plus accommodates a broad spectrum of sample containers—from conical-bottom polypropylene tubes (15–250 mL) to sealed centrifuge bottles—compatible with common laboratory reagents including ethanol, acetone, chloroform, and aqueous buffers. All rotor assemblies are certified per ISO 15195:2018 for calibration traceability and undergo dynamic balancing verification at 110% of maximum rated speed. The unit complies with CE marking directives (2014/30/EU EMC, 2014/35/EU LVD), RoHS 2011/65/EU, and supports GLP/GMP documentation workflows through optional audit-trail-enabled firmware (requires Titan CentriLog™ v3.2+). While the base model operates at ambient temperature, it accepts field-upgradable thermoelectric cooling modules (–10 °C to +40 °C range) for temperature-sensitive applications such as RNA isolation or enzyme fractionation.
Software & Data Management
The HDC-18KL Plus includes embedded firmware with non-volatile memory capable of storing up to 99 user-defined protocols, each configurable with ramp rate, hold time, final speed, and auto-brake settings. Optional USB-C connectivity enables protocol export/import and firmware updates via Titan CentriLog™ desktop software (Windows/macOS). When paired with the CentriLog™ Audit Module, the system generates timestamped, tamper-evident log files compliant with FDA 21 CFR Part 11 requirements—including operator ID, parameter changes, run completion status, and error events—facilitating regulatory submissions and internal quality audits.
Applications
- Routine pelleting of eukaryotic and prokaryotic cells prior to lysis or cryopreservation
- Clarification of clarified lysates and purification of inclusion bodies
- Isolation of mitochondria, nuclei, and microsomal fractions from tissue homogenates
- Concentration and size-based separation of extracellular vesicles (e.g., exosomes, microvesicles)
- Preparative centrifugation of polymer emulsions, colloidal suspensions, and catalyst slurries in materials science labs
- High-throughput sample preparation for downstream LC-MS, NGS library prep, and ELISA workflows
FAQ
Is the HDC-18KL Plus compatible with refrigerated operation?
Yes—optional thermoelectric cooling modules can be installed to maintain chamber temperatures between –10 °C and +40 °C during operation.
What rotor types are supported out of the box?
The base configuration supports fixed-angle rotors only; swing-bucket and vertical rotors require separate validation and are not included or recommended without factory certification.
Does the unit meet international safety standards for laboratory use?
Yes—it conforms to IEC 61010-2-020, CE, and RoHS directives, and all rotors carry ISO 15195 traceable calibration certificates.
Can run parameters be exported for quality documentation?
Yes—via USB-C and Titan CentriLog™ software, users may generate CSV-formatted run logs with full metadata for SOP compliance and audit readiness.
Is rotor balancing required before each run?
Yes—manual balancing using matched tube masses remains mandatory; the instrument does not include automatic imbalance detection beyond its mechanical cut-off threshold (≥5 mm radial displacement).
