Sanotac CS1040 Stainless Steel Ultra-High-Pressure HPLC Pump

Overview

The Sanotac CS1040 is an ultra-high-pressure metering pump engineered for precision fluid delivery in demanding analytical and process-critical applications. Designed around a dual-plunger reciprocating architecture with active cam-profile compensation and electronic pulsation suppression, it operates on the principle of positive displacement with real-time compression compensation—ensuring volumetric accuracy across its full pressure range up to 40 MPa (6000 psi). Unlike conventional low-pressure peristaltic or diaphragm pumps, the CS1040 maintains flow integrity under high backpressure conditions typical of packed-bed reactors, supercritical fluid systems, and high-efficiency liquid chromatography (HPLC/UHPLC) configurations. Its robust 316L stainless steel fluid path—combined with sapphire check valves and ceramic plungers—delivers chemical compatibility with organic solvents, aqueous buffers, corrosive catalysts, and supercritical CO₂, making it suitable for both laboratory-scale method development and pilot-scale continuous-flow synthesis.

Key Features

• Multi-point flow calibration across the entire 0.01–100 mL/min range, enabling traceable accuracy per ISO/IEC 17025-compliant calibration protocols
• Integrated pressure pulsation suppression via dynamic cam curve optimization and real-time electronic feedback control (≤0.1 MPa residual pulsation)
• Column piston rear-washing mechanism to minimize seal wear and extend service intervals beyond 6,000 operating hours
• Compression compensation algorithm that dynamically adjusts stroke volume to offset fluid compressibility effects at pressures >20 MPa
• Zero-point drift correction and system protection pressure threshold setting to prevent over-pressurization during column blockage or thermal expansion events
• Dual-mode operation: volumetric (mL/min) or gravimetric (g/min) delivery with optional load-cell integration support

Sample Compatibility & Compliance

The CS1040 accommodates a broad spectrum of process fluids—including polar/nonpolar solvents (acetonitrile, THF, hexane), aggressive reagents (HF, concentrated HNO₃), ionic liquids, supercritical CO₂, and viscous polymer solutions (up to 500 cP at 25°C). All wetted surfaces conform to ASTM F899-22 for surgical-grade stainless steel and USP Class VI biocompatibility standards for PTFE components. The pump meets CE electromagnetic compatibility (EMC) Directive 2014/30/EU and Low Voltage Directive 2014/35/EU. For regulated environments, firmware supports audit-trail-enabled operation logs compliant with FDA 21 CFR Part 11 when paired with validated SCADA or LIMS interfaces.

Software & Data Management

The pump integrates natively with industrial control ecosystems via Modbus RTU/ASCII over RS485 and optional Modbus TCP, Profibus DP, or Profinet gateways. Local USB and RS232 ports enable direct connection to host PCs running Sanotac’s optional FlowControl Studio software—featuring real-time plotting of flow vs. pressure transients, programmable gradient profiles (linear, step, exponential), automated method recall (up to 99 stored programs), and CSV/PDF export of timestamped operational records. All data entries include operator ID, system time, pressure setpoint, actual flow deviation, and error codes—supporting GLP/GMP documentation requirements. Remote Ethernet (wired/wireless) and analog I/O (0–5 V / 4–20 mA) allow seamless DCS/PLC loop integration without intermediary gateways.

Applications

• Catalytic evaluation reactors requiring precise co-feeding of multiple reagents under 40 MPa hydrogen or syngas pressure
• Supercritical fluid chromatography (SFC) and extraction systems where CO₂ density modulation demands stable mass flow independent of temperature fluctuations
• Continuous-flow microreactor platforms for pharmaceutical API synthesis, including photoredox and electrochemical transformations
• Layer-by-layer deposition systems in battery electrode R&D, where nanosuspension dosing must maintain <0.1% RSD across 8-hour runs
• High-pressure hydrogenation test rigs simulating refinery hydrotreating conditions (e.g., ASTM D6304, ISO 12937)
• Preparative HPLC and flash chromatography systems scaling from 10 g to 500 g batch purification

FAQ

What is the maximum allowable inlet pressure for the CS1040?

The pump is designed for atmospheric or slightly pressurized inlet conditions (≤0.5 MPa); positive inlet pressure exceeding 0.3 MPa requires external backpressure regulation to avoid check valve cavitation.
Can the CS1040 be used with abrasive slurries?

No—it is not rated for particulate-laden fluids; suspended solids >1 µm will accelerate sapphire valve wear and compromise seal longevity.
Is firmware update capability available via USB?

Yes; field-upgradable firmware (v2.1+) supports enhanced PID tuning parameters and expanded Modbus register mapping for third-party SCADA integration.
Does the pump meet explosion-proof requirements for Zone 1 hazardous areas?

Not inherently; however, ATEX-certified motor variants (II 2G Ex db IIB T4 Gb) are available as custom-engineered configurations upon request.
How often is recalibration recommended under continuous operation?

Annual traceable calibration is advised; however, built-in self-diagnostic routines verify flow linearity and pressure response every 24 operational hours.