Drick DRK-75L20FGP Silicone Oil-Heated Standard Benchtop Freeze Dryer
| Brand | Drick |
|---|---|
| Origin | Shandong, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | DRK-75L20FGP |
| Instrument Type | Standard Shelf-Type Freeze Dryer |
| Application Scope | Laboratory Use |
| Lyophilization Area | 0.2 m² (Customizable) |
| Ultimate Vacuum | ≤10 Pa (No Load) |
| Condensate Capacity (24 h) | 6 L |
| Cold Trap Temperature | ≤−75 °C |
| Dimensions (W×D×H) | 1100 × 760 × 1300 mm (Door Excluded) |
Overview
The Drick DRK-75L20FGP is a silicone oil-heated, standard shelf-type benchtop freeze dryer engineered for reproducible, controlled lyophilization of heat-sensitive biological, pharmaceutical, and research-grade samples in laboratory environments. It operates on the fundamental principles of sublimation under deep vacuum: frozen water is removed directly from the solid phase to vapor without passing through the liquid state, preserving structural integrity, bioactivity, and chemical stability. The system integrates a high-efficiency dual-stage rotary vane vacuum pump, a low-temperature cold trap with a minimum operating temperature of −75 °C, and electrically heated shelves regulated via silicone oil circulation—enabling precise, uniform, and programmable shelf temperature control during primary and secondary drying stages. Designed for compliance with core laboratory operational requirements, it supports method development, stability testing, and small-batch production-scale drying across academic, QC, and R&D settings.
Key Features
- Silicone oil heating system ensures stable, uniform shelf temperature distribution (±0.5 °C) across the entire 0.2 m² drying area—critical for consistent cake morphology and residual moisture control.
- Cold trap rated at ≤−75 °C provides robust ice condensation capacity of up to 6 L per 24 hours, minimizing backstreaming and maintaining stable vacuum conditions during extended cycles.
- Ultimate vacuum performance of ≤10 Pa (no load) meets standard requirements for efficient sublimation kinetics in most lab-scale lyophilization protocols.
- Modular stainless-steel chamber and shelf assembly comply with ISO 13485-informed cleanability standards; all wetted surfaces are electropolished and non-porous for ease of decontamination.
- Integrated vacuum monitoring via digital Pirani gauge with real-time pressure logging; optional capacitance manometer upgrade available for high-accuracy absolute pressure measurement.
- Compact footprint (1100 × 760 × 1300 mm, door excluded) enables installation in standard laboratory fume hood alcoves or dedicated prep rooms without requiring external chillers or glycol loops.
Sample Compatibility & Compliance
The DRK-75L20FGP accommodates a broad range of sample formats including glass vials (10–50 mL), serum bottles, open petri dishes, and custom trays—suitable for proteins, monoclonal antibodies, vaccines, probiotics, botanical extracts, and polymer-based formulations. Its design aligns with foundational regulatory expectations for laboratory freeze dryers: vacuum integrity supports ICH Q5C stability study conditions; temperature uniformity meets USP recommendations for drying parameter validation; and material contact surfaces conform to FDA-compliant 316L stainless steel specifications. While not pre-certified for GMP manufacturing, the unit’s architecture—including sealed electrical enclosures, traceable calibration points, and audit-ready operation logs—facilitates qualification under GLP or internal SOP frameworks.
Software & Data Management
Equipped with an embedded 7-inch resistive touchscreen HMI, the system runs Drick’s proprietary LyoControl™ firmware, supporting multi-step drying profiles with independent ramp/hold parameters for shelf temperature, vacuum setpoint, and duration. All process data—including shelf temp, chamber pressure, cold trap temp, and elapsed time—is timestamped and stored internally (≥100 cycles). Export is supported via USB 2.0 to CSV format for integration into LIMS or statistical analysis platforms (e.g., JMP, Minitab). Optional Ethernet connectivity enables remote monitoring and basic SCADA-level supervision. Firmware adheres to ALCOA+ data integrity principles: each user session is authenticated, electronic records include operator ID and change history, and raw data files are write-protected post-cycle—supporting alignment with FDA 21 CFR Part 11 when paired with institutional electronic signature policies.
Applications
- Pharmaceutical R&D: Lyophilization cycle scouting for injectables, nasal sprays, and diagnostic reagents.
- Academic Research: Preservation of microbial cultures, enzyme preparations, and nanomaterial dispersions without aggregation.
- Food Science: Dehydration of probiotic powders, fruit extracts, and functional ingredients while retaining volatile compounds and antioxidant activity.
- Materials Testing: Preparation of porous scaffolds for tissue engineering and aerogel precursors requiring controlled pore architecture.
- Environmental Analysis: Stabilization of waterborne pathogen samples prior to PCR or ELISA-based detection.
- Quality Control Labs: Reference standard drying, moisture content verification (per ASTM E1868), and accelerated stability assessment per ICH Q1A(R3).
FAQ
What is the maximum batch volume this unit can handle?
Based on a typical loading density of 10–15 mL per vial and full shelf utilization, the DRK-75L20FGP supports up to ~1,200 standard 20 mL vials per cycle—equivalent to approximately 18–24 L of frozen solution volume.
Is the system compatible with stoppering under vacuum or nitrogen?
The base configuration does not include automatic stoppering; however, the chamber flange is designed to accept third-party stoppering modules with compatible O-ring sealing dimensions (DN200 ISO-KF). Manual stoppering via glove box integration is routinely performed by users.
Can shelf temperature be controlled independently during primary and secondary drying?
Yes—each drying stage may be assigned distinct shelf temperature ramps and holds, with real-time feedback from Pt100 sensors embedded beneath the shelf surface.
Does the unit meet CE or UL safety certification requirements?
The DRK-75L20FGP complies with IEC 61010-1:2010 for laboratory electrical equipment safety; CE marking is applied for export to EEA markets. UL listing is available upon request for North American installations, subject to regional voltage and grounding verification.
What maintenance intervals are recommended for the vacuum pump?
The integrated two-stage rotary vane pump requires oil replacement every 500 operating hours or semiannually—whichever occurs first—and annual inspection of inlet filters and exhaust baffles per manufacturer service bulletin DRK-LYO-SV-2023.
