Jihepu RX50 Research-Grade Upright Biological Microscope

Overview

The Jihepu RX50 is a research-grade upright biological microscope engineered for high-fidelity transmitted-light imaging in academic, clinical, and industrial life science laboratories. Built around an infinity-corrected optical architecture, the RX50 supports rigorous quantitative microscopy applications—including brightfield, phase contrast, differential interference contrast (DIC), darkfield, and fluorescence—without optical compromise. Its modular design integrates seamlessly with standardized C-mount imaging systems and third-party digital cameras, enabling reproducible image acquisition across multi-user environments. The system adheres to fundamental optical engineering principles defined in ISO 8578 (microscope nomenclature) and ISO 10934-1 (optical test methods), ensuring alignment with international calibration and validation expectations for regulated workflows.

Key Features

• Ultra-wide field of view (FOV) optics: High-eyepoint plan achromat and plan apochromat objectives paired with 25 mm and 26.5 mm field number eyepieces deliver exceptional flatness and edge-to-edge resolution—critical for morphometric analysis and tiled imaging.
• Ergonomic observation head options: Three interchangeable trinocular heads—30° inclined inverted-image, 30° inclined erect-image, and 5°–35° adjustable-angle inverted-image—support extended user sessions while maintaining parfocality and interpupillary adjustment (50–76 mm).
• Precision mechanical stage: Dual-layer composite stage (187 × 166 mm) with bidirectional linear rail drive, torque-adjustable tension control, and 0.1 mm positional repeatability ensures stability during time-lapse or multi-point acquisition protocols.
• DIC-ready nosepiece: 5-, 6-, or 7-position revolving objective turrets include dedicated slots for Nomarski prisms, enabling rapid switching between contrast modalities without realignment.
• Intelligent illumination system: Digitally controlled 100 W mercury lamp housing with centering/focusing adjustment, integrated LBD, ND6, and ND25 filters, and optional ECO infrared occupancy sensing for energy-efficient operation.
• Modular condenser suite: Swing-out achromatic condenser (NA 0.9) and universal condenser with built-in polarizer, phase annuli, darkfield stop, and DIC slider mounts support full contrast flexibility within a single platform.

Sample Compatibility & Compliance

The RX50 accommodates standard glass slides (26 × 76 mm), Petri dishes, multi-well plates, and custom specimen holders via adaptable stage inserts. Its transmitted-light configuration is optimized for fixed and live-cell specimens—including tissue sections, blood smears, microbial cultures, and zebrafish embryos—under physiological or chemically stabilized conditions. All optical components meet RoHS directives and are manufactured under ISO 13485-aligned quality management practices. While not certified as medical device hardware per FDA 21 CFR Part 820, the RX50’s mechanical and optical traceability supports integration into GLP-compliant validation packages and audit-ready documentation frameworks required by pharmaceutical QC labs and contract research organizations.

Software & Data Management

The RX50 operates as a hardware platform compatible with industry-standard imaging software suites—including NIS-Elements (Nikon), ZEN (Zeiss), and open-source tools such as Fiji/ImageJ—via C-mount adapters and USB-triggered camera interfaces. Optional Sony ICX695 TE-cooled CCD modules provide low-noise acquisition with hardware-level gain control and exposure synchronization. Fluorescence alignment routines, brightness memory presets, and DIC bias calibration utilities are embedded in the instrument’s firmware. For regulated environments, metadata logging (objective ID, magnification, exposure time, filter position) complies with ALCOA+ data integrity principles when captured through validated third-party acquisition software meeting FDA 21 CFR Part 11 requirements.

Applications

The RX50 serves as a primary imaging tool in cell biology for mitotic staging, organelle dynamics, and immunofluorescence colocalization; in pathology for routine histological evaluation and frozen-section analysis; in microbiology for Gram staining assessment and motility studies; and in developmental biology for live-embryo observation using phase contrast or DIC. Its robust mechanical architecture and thermal-stable optical train make it suitable for long-duration experiments requiring sub-micron positional fidelity—such as microinjection setup verification or electrophysiology slide alignment.

FAQ

Does the RX50 support DIC imaging out of the box?

Yes—the microscope includes DIC-compatible nosepieces with dedicated prism slots and a universal condenser equipped with removable Nomarski sliders. Full DIC functionality requires matching strain-free objectives and analyzer alignment, both supported by factory calibration documentation.
Can the RX50 be integrated into automated imaging workflows?

Absolutely. Standard C-mount interfaces, TTL shutter triggers, and RS-232/USB control ports enable seamless integration with motorized stages, autofocus modules, and commercial acquisition platforms. Custom API development is supported via documented serial command protocols.
Is service and technical support available outside China?

Jihepu maintains authorized service partners in North America, Europe, and Southeast Asia. Remote diagnostics, on-site calibration, and spare parts logistics are coordinated through regional distributors under formal service-level agreements.
What is the warranty coverage for the RX50?

The RX50 carries a 24-month limited warranty covering materials and workmanship. Extended service contracts—including annual optical recalibration, preventive maintenance, and priority response—are available through authorized channels.