Burrell Wrist-Action Shaker Model 075-785-04-36

Overview

The Burrell Wrist-Action Shaker Model 075-785-04-36 is a precision-engineered mechanical shaker designed specifically to meet the stringent motion requirements defined in the United States Pharmacopeia (USP) “Simethicone Foam Test.” Unlike orbital or reciprocating shakers, this device replicates the anatomically inspired wrist-action motion—characterized by a fixed 10° oscillation arc and a pivot radius of 13.3 ± 0.4 cm from the drive shaft center—ensuring high reproducibility in foam stability assessment of antifoaming agents. Its robust cast-aluminum housing, sealed induction motor, and low-vibration base provide long-term operational stability under continuous duty cycles. Engineered for ambient-temperature applications only, it delivers consistent mechanical agitation without thermal regulation, making it ideal for standardized pharmacopeial testing where temperature control is not required per protocol.

Key Features

• USP -compliant wrist-action mechanism with precisely calibrated 10° oscillation angle and 13.3 cm effective radius
• Adjustable speed range from 0 to 300 rpm in 30-rpm increments, enabling fine-tuned validation against pharmacopeial stroke rate tolerance (300 ± 10%)
• Single-platform design supporting up to four standard glass containers (e.g., USP Simethicone test bottles), with maximum load capacity of 10 lb (4.5 kg)
• Mechanical timer offering discrete 0–60 minute intervals or continuous run mode for extended assay protocols
• Integrated lever-arm locking system with slide-clamp retention ensures repeatable positioning and eliminates drift during operation
• 220 V, 50/60 Hz universal input compatibility with internal thermal overload protection
• Modular accessory interface supporting USP-certified Simethicone bottle holders and silicone emulsion-specific clamps (sold separately)

Sample Compatibility & Compliance

The Model 075-785-04-36 accommodates standard USP-compliant glass vessels—including 100 mL and 250 mL Simethicone test bottles—as well as custom-configured flasks, funnels, and specimen containers via optional mounting adapters. It conforms explicitly to USP , which mandates mechanical agitation at 300 strokes per minute through a 10° arc with a defined radial geometry. No additional calibration certificates are required for routine use in GLP- or GMP-regulated environments, though users must maintain documented verification of speed accuracy (±10% tolerance) and angular consistency per internal SOPs. The unit does not incorporate temperature control; therefore, all testing must be conducted within controlled ambient laboratory conditions (typically 20–25°C), aligned with USP general chapter stipulations.

Software & Data Management

This analog-controlled shaker operates without embedded firmware or digital interfaces. All operational parameters—including timing and speed—are set manually via front-panel dials and mechanical switches. While it lacks native data logging or remote connectivity, its simplicity ensures compliance with legacy validation frameworks requiring minimal electronic components. For laboratories subject to FDA 21 CFR Part 11 or Annex 11 requirements, manual logbooks or integrated LIMS entries can be used to record batch-specific run parameters (start time, duration, rpm setting, operator ID). Optional third-party RPM tachometers (e.g., contactless optical sensors) may be employed for periodic performance verification and audit readiness.

Applications

• Pharmaceutical quality control: Simethicone foam reduction assays per USP
• Formulation development of antifoaming agents in oral suspensions and emulsions
• Stability testing of surfactant-containing liquid dosage forms
• Research-scale evaluation of bubble coalescence kinetics in aqueous systems
• Environmental microbiology: gentle mixing of sedimentation samples without shear-induced cell lysis
• Academic teaching labs: demonstration of pharmacopeial methodology and mechanical agitation principles

FAQ

Does this shaker include temperature control?
No. The Model 075-785-04-36 operates exclusively at ambient temperature and is not equipped with heating or cooling elements.
Is the 10° oscillation angle adjustable?
No. The 10° arc is mechanically fixed per USP specifications and cannot be modified; alternative angles are not supported.
What is the recommended maintenance schedule?
Perform visual inspection of the drive linkage and clamp mechanism quarterly; lubricate pivot points annually with silicone-based grease; verify speed accuracy using a calibrated tachometer every six months.
Can I use non-USP bottles with this shaker?
Yes, provided they are securely mounted using compatible Burrell accessories (e.g., universal bottle clamps or custom adapter plates); however, USP compliance applies only when using certified Simethicone test vessels.
Is this instrument suitable for ISO 17025-accredited testing?
Yes—when operated within documented procedures, with traceable speed verification and environmental monitoring, it meets foundational metrological requirements for accredited laboratories conducting USP tests.