Shanghai Youyi (SHYY) LRH-250AL Low-Temperature Incubator
| Brand | Shanghai Youyi (SHYY) |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | LRH-250AL |
| Cooling Method | Compressor-Based Refrigeration |
| Temperature Range | −20 °C to +65 °C |
| Temperature Resolution | 0.1 °C |
| Temperature Uniformity | ±0.5 °C (both at high and low setpoints) |
| Chamber Capacity | 250 L |
| External Dimensions | 870 × 930 × 1810 mm (W × D × H) |
Overview
The Shanghai Youyi (SHYY) LRH-250AL Low-Temperature Incubator is an engineered environmental chamber designed for precise, stable, and reproducible temperature control across a wide operational range—from cryogenic preservation at −20 °C to elevated incubation at +65 °C. Built upon a dual-mode thermal architecture combining high-efficiency compressor-based refrigeration with PID-regulated heating, the unit maintains thermodynamic stability under variable ambient loads and extended operation cycles. Its core application domain spans biomedical sample integrity management—including serum, vaccine, and microbial culture storage—as well as controlled low-temperature testing of electronic components and specialty materials. Unlike standard benchtop incubators, the LRH-250AL integrates structural features aligned with GLP-compliant laboratory workflows: electrostatically coated cold-rolled steel housing, seamless mirror-finish stainless-steel interior, and fully adjustable shelving optimized for spatial flexibility and cleaning validation.
Key Features
- Robust mechanical construction: Cold-rolled steel exterior with epoxy-polyester powder coating; corrosion-resistant 304 stainless-steel inner chamber with radius-corner design for ISO 14644-compatible cleanability.
- Thermal performance: Dual-sensor feedback loop with microprocessor-driven PID algorithm ensures dynamic correction against drift—achieving ±0.5 °C uniformity across the full volume (per IEC 61000-4-2 test conditions: 20 °C ambient, 50% RH, no vibration or EMI interference).
- Human-machine interface: 5.7-inch backlit LCD touchscreen with menu-driven navigation supporting simultaneous display of setpoint, real-time chamber temperature, elapsed time, and programmable hold duration.
- Mobility & stability: Four-directional casters with independent locking feet enable safe repositioning without compromising leveling accuracy or vibration isolation.
- Power resilience: Non-volatile memory retains all user-defined parameters—including temperature profiles and alarm thresholds—during unexpected power interruption; automatic recovery upon restart without manual reconfiguration.
- Environmental compliance: Uses R134a and R406a refrigerants in accordance with Montreal Protocol Annex A Group II substance guidelines; energy consumption rated at 3.0 kW nominal input (tested per GB/T 23777–2009).
Sample Compatibility & Compliance
The LRH-250AL accommodates diverse biological and non-biological payloads, including but not limited to: cryopreserved cell suspensions, lyophilized reagents, diagnostic assay kits, calibration standards, and polymer-based reference materials. Its chamber geometry (580 × 500 × 850 mm internal W×D×H) supports stacking of standard ISO/IEC 17025-compliant storage containers up to 19 mm height per shelf level. The unit meets key regulatory prerequisites for laboratory use: electrical safety per GB 4793.1–2019 (equivalent to IEC 61010-1), electromagnetic compatibility per GB/T 18268.1–2010 (IEC 61326-1), and thermal performance verification traceable to national metrology institutes via factory calibration reports (NIST-traceable reference sensors included). Optional accessories—including RS485/USB data logging interfaces and embedded thermal printers—enable audit-ready documentation aligned with FDA 21 CFR Part 11 requirements when paired with validated software platforms.
Software & Data Management
While the base configuration operates via standalone firmware, optional connectivity modules support integration into centralized lab infrastructure. The RS485/USB interface enables bidirectional communication with third-party LIMS or ELN systems using Modbus RTU or ASCII protocols. Data export formats include CSV and XML, with timestamped records covering temperature history, alarm events, door-open intervals, and system diagnostics. When combined with the optional multi-segment programmable controller (up to 30 segments), users can define complex thermal profiles—including ramp-hold-cool sequences—for accelerated stability studies compliant with ICH Q1A(R2) guidelines. All digital logs include immutable metadata (user ID, session start/end, firmware version) to satisfy ALCOA+ principles for data integrity.
Applications
- Biomedical research: Long-term storage of human serum, monoclonal antibodies, and viral vectors at −20 °C; short-term incubation of psychrophilic bacterial cultures at 4–15 °C.
- Clinical diagnostics: Stabilization of PCR master mixes and ELISA substrates prior to assay execution; cold-chain validation for point-of-care device qualification.
- Pharmaceutical QA/QC: Accelerated degradation testing of excipients under controlled sub-zero conditions per USP .
- Materials science: Thermal cycling of printed circuit boards and optoelectronic assemblies to assess solder joint reliability at −20 °C.
- Public health laboratories: Environmental simulation for pathogen viability assessment during cold-chain transport modeling.
FAQ
What is the minimum operating temperature of the LRH-250AL?
The unit achieves and maintains −20 °C continuously under standard ambient conditions (20 °C, 50% RH, no direct airflow exposure).
Does the incubator support remote monitoring via Ethernet or Wi-Fi?
No native Ethernet/Wi-Fi module is integrated; however, USB-to-Ethernet adapters or industrial gateways may be deployed externally with appropriate driver support.
Is the stainless-steel interior electropolished for enhanced corrosion resistance?
The chamber uses standard 304 stainless steel with mechanical polishing—sufficient for routine disinfection with ethanol or quaternary ammonium compounds per CLSI M29-A4 recommendations.
Can the unit be validated for GMP environments?
Yes—the LRH-250AL is suitable for IQ/OQ/PQ execution when supported by documented calibration certificates, installation schematics, and operational boundary testing per ASTM E2500-13.
What is the maximum load capacity per shelf?
Each adjustable shelf supports up to 15 kg uniformly distributed load; total payload must remain within 80% of rated chamber volume to preserve thermal homogeneity.
