Shanghai Youyi LHS-300CA Temperature and Humidity Controlled Environmental Test Chamber

Overview

The Shanghai Youyi LHS-300CA is a precision-engineered upright environmental test chamber designed for stable, long-term temperature and humidity control under controlled laboratory conditions. It operates on the principle of forced-air convection with dual independent PID-controlled refrigeration and humidification subsystems, enabling reproducible simulation of climatic stress conditions across a wide operational envelope. Unlike general-purpose storage units, this chamber meets the engineering requirements of physical property testing protocols where thermal and hygroscopic stability directly influence material behavior—such as polymer aging, pharmaceutical stability studies (ICH Q1A–Q1E), electronic component qualification (JEDEC JESD22-A108), and biological sample integrity preservation. Its air-cooled refrigeration system utilizes environmentally compliant R134a/R406a blended refrigerant, eliminating ozone-depleting substances while maintaining thermodynamic efficiency in ambient environments up to 30°C.

Key Features

• Microprocessor-based 5.7-inch LCD controller with intuitive menu-driven interface supporting up to 99 programmable cycles, each comprising 30 segments with individual time settings (up to 99 h 59 min per segment); ideal for ICH-compliant accelerated stability testing.
• Double-door structure with tempered glass observation window and silicone-sealed inner door gasket ensures minimal thermal leakage and uninterrupted visual monitoring without compromising chamber stability.
• High-efficiency air circulation system featuring optimized wind tunnel design and rear-mounted centrifugal blower delivers uniform temperature distribution (±0.5°C) and humidity homogeneity (±3% RH) throughout the 300 L working volume.
• Electropolished mirror-finish stainless steel interior with radius-corner construction minimizes microbial retention points and simplifies cleaning validation per GLP/GMP guidelines.
• Self-designed immersion-type electric heating element humidification system with built-in water reservoir and high-accuracy capacitive humidity sensor (traceable to NIST standards) enables precise RH control between 30–95% RH.
• Four-point adjustable stainless steel shelving system (standard: 3 shelves; max: 23 shelves) allows flexible load configuration while maintaining airflow integrity and thermal mass balance.
• Integrated castor wheels with locking mechanism and leveling feet ensure both mobility during facility reconfiguration and mechanical stability during vibration-sensitive measurements.

Sample Compatibility & Compliance

The LHS-300CA accommodates diverse sample types including vials, trays, petri dishes, PCB assemblies, polymer specimens, and sealed biological containers. Its chamber dimensions (580 × 540 × 950 mm) support ISO 17025-accredited calibration geometries and comply with spatial requirements for ASTM D4332 (conditioning of plastics), ISO 22196 (antimicrobial activity testing), and USP (storage conditions for drug substances). The unit is compatible with external data logging via optional RS485/USB interfaces, supporting audit-trail-capable software for FDA 21 CFR Part 11 compliance when paired with validated third-party platforms. All electrical components meet CE safety directives (EN 61000-6-3, EN 61000-6-4), and refrigerant handling conforms to EU F-Gas Regulation (EU No 517/2014).

Software & Data Management

While the standard controller provides local cycle programming and real-time parameter display, optional connectivity modules enable integration into centralized laboratory information management systems (LIMS). The USB/RS485 interface supports ASCII-based command protocols for automated script execution and time-stamped data export (CSV/TXT). When used with validated third-party software, the chamber supports electronic signature workflows, user-access-level permissions, and automatic generation of IQ/OQ documentation templates aligned with ISO/IEC 17025 clause 5.5.3. Optional embedded thermal printer provides hard-copy records meeting GLP Annex 11 traceability requirements.

Applications

• Accelerated stability testing of pharmaceuticals, biologics, and medical devices per ICH Q1 series guidelines.
• Conditioning of polymeric materials prior to tensile, impact, or dielectric testing (ASTM D618, ISO 291).
• Environmental stress screening of printed circuit boards and semiconductor packages (JEDEC JESD22-A104, MIL-STD-810G).
• Long-term storage and viability assessment of vaccines, plasma derivatives, and cryopreserved cell lines at defined sub-zero and ambient-humidity setpoints.
• Calibration verification of hygrometers, thermistors, and data loggers using traceable reference standards.
• Corrosion resistance evaluation of metallic coatings under cyclic humidity exposure (ISO 6270-2).

FAQ

What is the maximum allowable ambient temperature for reliable operation?
The chamber is rated for continuous use in ambient environments ≤30°C and ≤70% RH (non-condensing), per manufacturer’s performance validation protocol.
Does the unit support remote monitoring via Ethernet or Wi-Fi?
No native Ethernet/Wi-Fi capability is included; however, third-party IoT gateways can be integrated via the RS485 port using Modbus RTU protocol.
Is the humidity sensor factory-calibrated and traceable?
Yes—the capacitive humidity sensor is pre-calibrated against NIST-traceable reference hygrometers and includes a certificate of calibration valid for 12 months from shipment.
Can the chamber be validated for GxP environments?
Yes—its architecture supports full IQ/OQ/PQ execution. Documentation packages, including FAT/SAT reports and alarm response logs, are available upon request.
What safety protections are implemented against overheating or over-humidification?
Independent mechanical high-limit thermostat (adjustable up to 90°C), compressor overheat protection, and auto-shutoff on water reservoir depletion are standard. An optional independent over-temperature alarm module is available as an accessory.