Shanghai RightOne LHS-250CA Temperature and Humidity Controlled Environmental Test Chamber

Overview

The Shanghai RightOne LHS-250CA is a precision-engineered upright environmental test chamber designed for stable, long-term temperature and humidity control in scientific and industrial laboratories. It operates on the principle of active thermoelectric cooling combined with PID-regulated resistive heating and a dedicated steam-based humidification system—enabling simultaneous, independent control of temperature and relative humidity across a broad operational envelope. The chamber is engineered for applications requiring strict environmental conditioning of biological specimens, pharmaceutical products, electronic components, and polymeric materials under reproducible, traceable conditions. Its dual-layer insulated door with sealed double-glazed viewing window minimizes thermal bridging and ensures minimal disturbance during observation—a critical requirement for stability-sensitive protocols such as vaccine storage, cell culture pre-conditioning, or accelerated aging studies per ISO 14644 or ICH Q1A(R2).

Key Features

• Microprocessor-based PID controller with 5.7-inch backlit LCD interface supporting up to 99 programmable cycles; each cycle configurable with up to 30 segments, and each segment adjustable to 99 hours 99 minutes—ideal for complex ramp-hold-dwell sequences required in stability testing (e.g., ICH Q5C, ASTM D4332).
• Internally constructed from electropolished mirror-finish stainless steel (SUS304), featuring radius-rounded corners and removable, height-adjustable shelves (3 standard / up to 19 maximum) to facilitate cleaning, validation, and flexible sample loading.
• Environmentally compliant refrigeration system utilizing R134a and R406a mixed refrigerants—zero ozone depletion potential (ODP = 0), low global warming potential (GWP < 1430), and certified to meet EU F-Gas Regulation (EU) No 517/2014.
• Integrated humidity generation via stainless-steel sheathed immersion heaters in a self-contained water reservoir, paired with a high-accuracy capacitive humidity sensor (±1.5 %RH accuracy, 0.1 %RH resolution) mounted within the air circulation path for real-time feedback control.
• Optimized airflow architecture employing rear-mounted centrifugal fans and multi-directional ducted air distribution—ensuring ≤±0.5 °C temperature uniformity and ≤±3 %RH humidity uniformity (measured at 9 points per IEC 60068-3-5) across the full working volume.
• Mobile base with four swiveling casters (two with mechanical locking brakes) and independently adjustable leveling feet—enabling precise horizontal alignment on non-uniform laboratory flooring without compromising vibration isolation.

Sample Compatibility & Compliance

The LHS-250CA accommodates diverse sample types—including cryopreserved plasma units (in standard 50 mL conical tubes), lyophilized biologics vials, PCB assemblies, elastomeric seals, and polymer film coupons—within its 250 L internal volume (580 × 500 × 850 mm). Its operating range (−10 to +80 °C, 30–95 %RH) aligns with key regulatory test conditions specified in USP , ISO 14644-3 (cleanroom environmental monitoring), and ASTM D7002 (plastic aging). The chamber meets electromagnetic compatibility requirements per EN 61326-1 and safety standards per EN 61010-1. Optional accessories—including an independent overtemperature alarm module, BOD-compatible power outlets, and 25 mm/50 mm calibrated access ports—support GxP-compliant qualification (IQ/OQ/PQ) and integration into validated workflows.

Software & Data Management

Equipped with standard RS485 communication port and optional USB interface, the LHS-250CA supports bidirectional data exchange with third-party SCADA systems or custom LabVIEW/Python-based monitoring platforms. When paired with the optional dedicated software package, users gain access to audit-trail-enabled logging (meeting FDA 21 CFR Part 11 requirements), real-time graphing of temperature/humidity trends, automatic report generation (PDF/CSV), and remote parameter adjustment via secure LAN connection. All logged data include timestamp, operator ID (if authenticated), and system status flags—ensuring full traceability for GLP and GMP environments.

Applications

• Long-term stability storage of blood plasma, monoclonal antibodies, and mRNA vaccine intermediates under controlled cold-chain conditions (−10 to +25 °C, 30–60 %RH).
• Accelerated shelf-life testing of medical device packaging per ISO 11607-1, including peel strength evaluation after exposure to high-humidity cycling (e.g., 40 °C/95 %RH → 25 °C/30 %RH).
• Pre-conditioning of lithium-ion battery cells prior to electrochemical characterization, following JEDEC JESD22-A119 humidity soak protocols.
• Environmental stress screening of aerospace-grade adhesives and composite laminates per MIL-STD-810H Method 507.6 (humidity exposure).
• Humidity-dependent degradation studies of hygroscopic APIs, including moisture sorption isotherm mapping using gravimetric vapor sorption (GVS) methodology.

FAQ

What is the chamber’s temperature and humidity recovery time after door opening?
Typical recovery to ±0.5 °C and ±3 %RH from a 30-second door opening event (at 25 °C/50 %RH setpoint) is ≤12 minutes, verified per IEC 60068-3-6.
Can the unit be validated for GMP use?
Yes—the LHS-250CA supports full IQ/OQ/PQ documentation packages, including sensor calibration certificates (NIST-traceable), uniformity mapping reports, and alarm response verification logs.
Is external water supply required for humidification?
No—the integrated 3.2 L reservoir supports continuous operation for up to 72 hours at 95 %RH; distilled or deionized water is recommended to prevent scaling.
What safety protections are built-in?
Overtemperature cutoff (dual independent sensors), compressor high-pressure shutdown, humidity sensor failure detection, door-open alarm, and ground-fault circuit interruption (GFCI) on all power circuits.
Does the controller support Ethernet or Wi-Fi connectivity?
Standard configuration includes RS485 only; Ethernet/Wi-Fi modules are available as factory-installed options upon request, enabling integration with enterprise-level MES or LIMS platforms.