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Yoyi LHS-500SC 500L Vertical Temperature and Humidity Controlled Environmental Chamber

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Brand Yoyi
Origin Shanghai, China
Manufacturer Type Direct Manufacturer
Model LHS-500SC
Instrument Type Vertical Chamber
Temperature Range 15–60°C (with humidification), 10–60°C (without humidification)
Humidity Range 50–85% RH
Temperature Uniformity ±1°C
Temperature Fluctuation ±1°C
Humidity Uniformity ±5% RH
Humidity Fluctuation ±1% RH
Interior Dimensions (W×D×H) 800×700×900 mm

Overview

The Yoyi LHS-500SC is a vertically oriented, high-capacity (500 L) temperature and humidity controlled environmental chamber engineered for precise, reproducible simulation of long-term stability, aging, and accelerated testing conditions. It operates on a dual-control principle—combining PID-regulated resistive heating with a dedicated electrically heated water reservoir system for humidification, and a forced-air convection architecture using optimized airflow ducting to ensure spatial uniformity across the entire working volume. Designed in accordance with GB/T 10586–2006 (Technical Specifications for Damp Heat Test Chambers) and GB/T 2424.6–2006 (Performance Verification of Temperature/Humidity Chambers), the LHS-500SC delivers traceable, standards-aligned performance suitable for GLP-compliant laboratories and regulated quality assurance environments.

Key Features

  • Mirror-finish stainless steel interior with seamless, radius-cornered construction for ease of cleaning and resistance to microbial retention.
  • Eco-friendly refrigerant R134a/R406a cooling system integrated with high-efficiency axial fans and thermally balanced air ducts to maintain ±1°C temperature uniformity and ±1°C fluctuation under steady-state operation.
  • Microprocessor-based PID controller with intuitive large LCD interface supporting up to 99 programmable cycles, each comprising 30 segments (max. 99 h 99 min per segment), enabling complex multi-step environmental profiles for ICH Q1/Q5 stability studies.
  • Dual-layer door assembly featuring tempered glass observation window with silicone-gasketed sealing, minimizing thermal leakage while permitting real-time visual monitoring without chamber disturbance.
  • Modular castor base with omnidirectional wheels and independent locking leveling feet for stable positioning and safe relocation in shared lab spaces.
  • Self-designed immersion-type heating element within an internal water reservoir ensures consistent vapor generation and tight humidity control (±5% RH deviation, 50–85% RH range) without external steam generators or ultrasonic misters.

Sample Compatibility & Compliance

The LHS-500SC accommodates diverse sample formats—including stacked Petri dishes, multi-well plates, vials, packaged pharmaceuticals, polymer specimens, textile swatches, and electronic subassemblies—within its 800 × 700 × 900 mm (W×D×H) workspace. Adjustable stainless steel shelving (standard configuration: two load-bearing trays) supports flexible load distribution. The chamber meets national metrological verification requirements per GJB/J 3827–1999 and conforms to ISO/IEC 17025 calibration traceability frameworks when operated with certified reference sensors. Its design facilitates integration into FDA 21 CFR Part 11–compliant workflows when paired with optional RS485 communication modules and validated data logging software.

Software & Data Management

While the base unit features embedded firmware with local cycle storage and real-time parameter display, optional RS485 serial interface enables bidirectional communication with third-party SCADA systems or LIMS platforms. The included PC software (sold separately) supports export of time-stamped temperature/humidity logs in CSV format, configurable alarm thresholds, and audit-trail-enabled user access control. Optional embedded thermal printer provides hard-copy record generation aligned with ALCOA+ data integrity principles. All digital outputs are timestamped and retain metadata including operator ID, cycle name, and environmental setpoints—supporting retrospective review during regulatory inspections.

Applications

This chamber serves as a foundational platform for accelerated stability testing per ICH guidelines (Q1A–Q1E), shelf-life determination of sterile and non-sterile pharmaceutical products, biocompatibility evaluation of medical device materials (ISO 10993–12), polymer degradation analysis (ASTM D3045), textile colorfastness assessment (ISO 105-B02), and microbiological growth inhibition studies (USP ). Its robust thermal-hygrometric fidelity also supports QC validation of packaging barrier performance, battery thermal cycling protocols, and pre-conditioning of sensors prior to calibration.

FAQ

What is the maximum allowable ambient operating temperature for the LHS-500SC?
The chamber is rated for use in ambient environments ≤30°C and ≤70% RH (non-condensing), as specified in GB/T 10586–2006.
Can the LHS-500SC operate continuously at 60°C and 85% RH?
Yes—continuous operation at the upper limits of its specified range is supported, provided adequate ventilation and ambient cooling capacity are maintained.
Is the humidity sensor calibrated and traceable to national standards?
The integrated capacitive humidity sensor is factory-calibrated; users may perform field verification using NIST-traceable hygrometers per ISO/IEC 17025 procedures.
Does the unit include over-temperature and over-humidity safety cutoffs?
Yes—a redundant independent mechanical thermostat (optional add-on) and software-enforced upper limits prevent uncontrolled excursions beyond user-defined thresholds.
What power supply configuration is required for installation?
Single-phase AC 220 V ±10%, 50 Hz, with dedicated 16 A circuit breaker and proper grounding—no three-phase input is needed.

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