Yoyilab LRH-500 Biochemical Incubator

Overview

The Yoyilab LRH-500 Biochemical Incubator is a precision-engineered, dual-mode (heating and refrigeration) environmental chamber designed for stable, long-term cultivation and preservation of microorganisms—including bacteria, yeasts, molds, and fungi—under controlled thermal conditions. Built upon a robust Cu-free compressor cooling system and PID-regulated resistive heating architecture, the LRH-500 maintains precise temperature setpoints across its full operational range of 0–65 °C. Its design adheres to core requirements for biochemical incubation in GLP-compliant laboratories: minimal thermal drift, high spatial uniformity, and resilience against ambient fluctuations (tested at 20 °C/50% RH, no vibration or EMI). Unlike generic warming cabinets, this unit meets functional specifications relevant to BOD5 assays, microbial viability studies, pharmaceutical stability testing per ICH Q1, and seed bank storage protocols where reproducible thermal environments are non-negotiable.

Key Features

• Microprocessor-controlled PID temperature regulation with 0.1 °C resolution and adaptive tuning—ensuring rapid recovery after door opening and minimizing overshoot during ramping.
• Dual-layer insulated door with double-sealed viewing window; reduces heat transfer by >40% compared to single-pane designs and prevents condensation under humid conditions.
• Electropolished mirror-finish stainless-steel interior (304 grade) with rounded corners and removable, height-adjustable shelves—facilitating ISO 14644-compliant cleaning and validation of residue-free surfaces.
• Four-point independent leveling feet with locking casters (two swivel, two fixed)—enabling precise horizontal alignment on uneven lab floors and secure repositioning without disassembly.
• 5.7-inch backlit LCD interface with menu-driven navigation: displays real-time chamber temperature, setpoint, elapsed time, remaining timer duration, and alarm status simultaneously.
• Power-loss recovery function with non-volatile memory retention—automatically restores prior settings (setpoint, timer, PID parameters) following grid interruption or unexpected shutdown.
• Independent over-temperature cut-off circuit (hardware-based, separate from main controller) compliant with IEC 61000-4-2/ESD immunity standards—triggers audible/visual alarm and halts heating if deviation exceeds user-defined threshold.

Sample Compatibility & Compliance

The LRH-500 accommodates standard microbiological vessels including Petri dishes (up to 150 mm), test tubes (16 × 150 mm), culture flasks (up to 2 L), and multi-well plates. Its uniformity profile (±1.5 °C at 25 °C, per ISO 27874:2015 Annex C) supports applications requiring traceable thermal consistency—such as ASTM D5210-92 (BOD incubation), USP (microbial growth promotion testing), and EN ISO 8589:2020 (sensory analysis conditioning). The unit is CE-marked for EMC and LVD compliance (2014/30/EU and 2014/35/EU); optional RS485 interface enables integration into facility-wide monitoring systems compliant with FDA 21 CFR Part 11 when paired with validated data logging software.

Software & Data Management

While the base model operates via standalone firmware, optional accessories extend digital functionality: an RS485 communication module (with Modbus RTU protocol support) allows bidirectional control and real-time data streaming to SCADA or LIMS platforms. The optional embedded thermal printer provides timestamped hardcopy logs of temperature history (±0.1 °C resolution, 1-min intervals), satisfying audit trail requirements per ISO/IEC 17025:2017 Clause 7.7. For advanced scheduling, the programmable temperature controller (optional add-on) supports up to 30 segments with ramp/soak profiles—ideal for simulating diurnal cycles in plant physiology or gradual acclimation in fungal strain adaptation studies.

Applications

• Environmental microbiology: BOD₅ incubation per APHA Standard Methods 5210B and ISO 5815-1.
• Pharmaceutical QC: Growth promotion testing of media per USP , , and EP 2.6.12.
• Agricultural research: Seed germination trials, rhizobial culture maintenance, and mycotoxin production studies.
• Food safety labs: Enumeration of aerobic plate counts (ISO 4833-1), coliform enrichment (ISO 16649-2), and lactic acid bacteria propagation.
• Academic teaching labs: Hands-on instruction in microbial kinetics, thermal death time modeling, and environmental stress response assays.

FAQ

What is the maximum ambient temperature for reliable operation?
The LRH-500 is rated for continuous use at ambient temperatures between +5 °C and +30 °C. Operation above 30 °C may reduce cooling capacity and increase compressor duty cycle.
Does the unit support humidity control?
No—the LRH-500 is a dry-air incubator. Humidity management requires external humidification systems or dedicated CO₂/humidity incubators.
Can the incubator be validated for GMP environments?
Yes. IQ/OQ documentation templates are available upon request. The unit’s mechanical design, sensor redundancy, and alarm hierarchy align with Annex 15 (EU GMP) and WHO TRS 961 requirements for equipment qualification.
Is the stainless-steel interior electropolished to meet pharmaceutical surface finish standards?
Yes—the interior surface achieves Ra ≤ 0.8 µm per ASTM B967, verified via profilometry reports supplied with each unit.
What calibration certificates are provided with shipment?
A factory-issued temperature uniformity and accuracy verification report (per ISO/IEC 17025-accredited third-party lab) is included. NIST-traceable probe calibration certificates are available as an optional service.