Bohui BH5100T Medical Flame Atomic Absorption Spectrometer
| Brand | Bohui |
|---|---|
| Origin | Beijing, China |
| Model | BH5100T |
| Analysis Method | Flame Atomic Absorption Spectrometry (FAAS) |
| Simultaneous Multi-Element Detection | Cu, Zn, Ca, Mg, Fe |
| Atomizer | Pre-mixed 100 mm single-slit titanium burner |
| Wavelength Range | 190–650 nm |
| Spectral Bandwidth | 0.15–2.0 nm |
| Absorbance Range | 0–2 Abs |
| Baseline Stability | ≤0.005 Abs (30 min, unignited) |
| Characteristic Concentrations (Cu/Zn/Ca/Mg/Fe) | ≤0.035 / ≤0.015 / ≤0.080 / ≤0.040 / ≤1.05 mg/L per 1% absorption |
| Precision | ≤1.0% RSD (Abs > 0.1) |
| Sample Volume | 20 µL (Enhanced) or 40 µL (Standard) whole blood |
| Power Supply | AC 220 ± 22 V, 50 ± 1 Hz, 300 VA |
| Dimensions | 720 × 520 × 275 mm |
| Operating Environment | 10–30 °C, RH ≤70%, no vibration/corrosive gases/EMI |
| Safety Compliance | Overpressure Category II, integrated acetylene flashback arrestor, pressure/flow dual monitoring, automatic gas cutoff on power loss or low air pressure |
| Software | Dedicated clinical data management system with GLP-compliant audit trail, automated calculation, storage, and report generation (graphical + tabular output) |
Overview
The Bohui BH5100T Medical Flame Atomic Absorption Spectrometer is a CE-marked, NMPA-registered (Registration No.: Jing Yao Jian Xie (Zhun) Zi 2011 Di 2400258 Hao) clinical instrument engineered for rapid, simultaneous quantification of five essential trace elements—copper (Cu), zinc (Zn), calcium (Ca), magnesium (Mg), and iron (Fe)—directly in whole blood specimens. It operates on the fundamental principle of flame atomic absorption spectrometry (FAAS): liquid samples are pneumatically nebulized into a fine aerosol, desolvated and atomized in a pre-mixed air-acetylene flame, generating ground-state free atoms that selectively absorb characteristic radiation emitted by element-specific hollow cathode lamps. The magnitude of absorption at each element’s primary resonance line is linearly proportional to its concentration in the sample matrix, enabling precise, calibration-based quantitation. Designed specifically for high-throughput clinical laboratories, the BH5100T eliminates sequential elemental analysis by integrating dual composite lamp architecture and patented multi-channel angular optical alignment—ensuring trace-level sensitivity, inter-element spectral isolation, and analytical robustness under routine diagnostic conditions.
Key Features
- Patented Multi-Channel Angular Optical Design: Two composite hollow cathode lamps—Cu/Zn/Ca and Mg/Fe—are mounted at precisely calibrated angles relative to the atomization path. This geometry enables time-shared illumination without mechanical lamp rotation or repositioning, eliminating downtime associated with lamp exchange in conventional single-channel systems.
- Dual Composite Hollow Cathode Lamps: Separation of high-sensitivity (Cu, Zn) and medium-sensitivity (Ca, Mg, Fe) elements across two optimized lamps prevents spectral interference, maintains stable emission intensity, and extends lamp service life beyond 5,000 burn-hours under standard operating conditions.
- Titanium Alloy Burner Head: A 100 mm single-slit pre-mixed burner constructed entirely from medical-grade titanium ensures exceptional resistance to oxidation, corrosion, and thermal fatigue—even during extended daily operation with saline-rich biological matrices.
- PTFE Nebulization Chamber: Featuring a conical internal geometry and rear-drain configuration, the chamber minimizes memory effects through laminar flow dynamics and controlled condensate removal. Its fluorinated surface provides uniform wetting characteristics, ensuring pulse-free waste effluent and reproducible aerosol generation.
- Integrated Safety Architecture: Complies with IEC 61010-1:2010 safety requirements for laboratory equipment. Includes fail-safe acetylene flashback arrestor, dual-stage pressure and flow monitoring, automatic fuel cutoff on power interruption or sub-threshold air pressure, and explosion-resistant burner housing.
Sample Compatibility & Compliance
The BH5100T is validated for direct analysis of anticoagulated (EDTA-K₂) whole blood without dilution or digestion—supporting both enhanced (20 µL) and standard (40 µL) protocols. Sample introduction is fully automated via peristaltic pump and precision capillary delivery. Instrument validation adheres to CLSI EP15-A3 and ISO 15197:2013 guidelines for clinical analyzer performance. Regulatory documentation includes full technical file submission compliant with China NMPA Class II medical device requirements and conformity assessment per GB/T 21415–2008 (equivalent to ISO 17511). Data integrity meets ALCOA+ principles; software supports 21 CFR Part 11-compliant electronic signatures, role-based access control, and immutable audit trails for all calibration, maintenance, and result events.
Software & Data Management
The proprietary Bohui Clinical Analyzer Software (v4.2+) runs on Windows 10 IoT Enterprise and provides a secure, FDA-auditable workflow environment. Functions include automated multi-point calibration curve generation (linear/log-linear fitting), real-time QC charting (Levey-Jennings, Westgard rules), batch processing with specimen ID tracking, and export to LIS via ASTM E1384-compliant HL7 v2.5 interface. All raw absorbance data, lamp current logs, flame status timestamps, and operator actions are permanently archived with SHA-256 hash verification. Reports include quantitative results, reference intervals (age- and sex-stratified per Chinese Clinical Laboratory Reference Intervals Standard WS/T 402–2012), trend graphs, and QC summary dashboards—printable in PDF/A-1b format for long-term archival.
Applications
The BH5100T serves as a frontline tool in clinical nutrition assessment, pediatric metabolic screening, geriatric trace element monitoring, and chronic disease management (e.g., renal failure, cirrhosis, inflammatory bowel disease). Its ability to quantify five physiologically interdependent cations within a single 4-second measurement cycle supports evidence-based interpretation of elemental imbalances—such as Zn/Cu ratio in Wilson’s disease evaluation or Mg/Ca correlation in arrhythmia risk stratification. The system is routinely deployed in provincial CDC laboratories, tertiary hospital clinical chemistry departments, and maternal-child health centers where throughput, regulatory compliance, and operational simplicity are critical success factors.
FAQ
Is the BH5100T suitable for serum or plasma analysis?
Yes—though optimized for whole blood, validated protocols exist for serum and lithium-heparin plasma using 50 µL aliquots and matrix-matched calibration standards.
Does the system support external calibration verification standards?
Yes—software allows import of third-party CRM values (e.g., Seronorm™ Trace Elements Whole Blood) for independent accuracy verification and bias assessment.
What maintenance intervals are recommended for optimal performance?
Nebulizer capillary cleaning every 200 analyses; burner head ultrasonic cleaning weekly; lamp alignment verification quarterly; full optical path inspection annually per manufacturer’s PM checklist.
Can raw spectral data be exported for secondary analysis?
No—the system outputs processed absorbance values only; raw detector voltage waveforms are not accessible to preserve clinical data integrity and regulatory compliance.
Is remote diagnostics supported?
Yes—optional VPN-enabled remote support module permits authorized Bohui engineers to initiate secure screen-sharing sessions for troubleshooting, subject to hospital IT security policy approval.
