Liquid Chromatography Mass Spectrometry
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| Brand | Bruker |
|---|---|
| Origin | Germany |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | timsTOF HT |
| Instrument Type | Trapped Ion Mobility Spectrometry (TIMS) Mass Spectrometer |
| Technology | Parallel Accumulation–Serial Fragmentation (PASEF®), CCS-enabled 4D-Proteomics |
| Brand | Bruker |
|---|---|
| Origin | Germany |
| Instrument Type | Trapped Ion Mobility Spectrometry–Time-of-Flight Mass Spectrometer (TIMS-TOF MS) |
| Ionization Modes | Dual MALDI/ESI |
| Application Focus | Label-free Ultra-High-Throughput Screening (uHTS) in Drug Discovery |
| Software Platform | MALDI PharmaPulse® 2023 |
| Compliance Ready | GLP/GMP-aligned data handling, 21 CFR Part 11–compatible audit trail (via optional software configuration) |
| Throughput | Up to 3 samples/sec on 1536-well plates |
| CCS Calibration | Yes, with internal standards |
| MALDI Source | 10 kHz smartbeam™ 3D laser, MALDI-2 option available |
| Sample Handling | Robotic MALDI target auto-loader, disposable targets (96–1536-well compatible) |
| Data Export | Native support for Genedata Screener®, Assay Explorer, and other HTS informatics platforms |
| Brand | Bruker |
|---|---|
| Origin | Germany |
| Model | timsTOF Pro 2 |
| Instrument Type | Trapped Ion Mobility Spectrometry (TIMS) Mass Spectrometer |
| Application Domain | Specialized Omics Research (Proteomics, Lipidomics, Phosphoproteomics, Clinical Biomarker Discovery) |
| Regulatory Context | Compliant with GLP/GMP data integrity requirements |
| Brand | Bruker |
|---|---|
| Origin | Germany |
| Instrument Type | Trapped Ion Mobility Spectrometry–Time-of-Flight Mass Spectrometer (TIMS-TOF) |
| Model | timsTOF SCP |
| Application Domain | Specialized Single-Cell Proteomics, Immunopeptidomics, PTM Analysis, Epigenoproteomics |
| Ion Source | Optimized Dual-Orthogonal Reflectron Ion Source with 1-mm Transfer Capillary |
| Vacuum Architecture | 8-stage Differential Vacuum System |
| Acquisition Mode | dia-PASEF® (Data-Independent Acquisition Parallel Accumulation–Serial Fragmentation) |
| CCS Capability | Yes, Collision Cross Section–enabled Ion Mobility Separation |
| Scan Speed | >120 Hz MS/MS |
| Software Platform | timsControl, PaSER (Real-time Parallel Database Search Engine), Compatible with MaxQuant/Perseus, PEAKS Studio |
| Data Format | Open .d Format (Bruker) |
| Regulatory Compliance | Supports 21 CFR Part 11–compliant workflows (audit trail, electronic signatures, data integrity controls) |
| Brand | Bruker |
|---|---|
| Origin | Germany |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | timsUltra AIP |
| Instrument Type | Trapped Ion Mobility Spectrometry (TIMS) Mass Spectrometer |
| Application Scope | Specialized Proteomics & Multi-Omics Platforms |
| Software Integration | TIMS PASEF®, TIMScore™, DIA-NN 4D-Proteomics™, Spectronaut® 20, ICC 2.0 |
| Brand | Elite |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Instrument Type | Tandem Quadrupole (QqQ) |
| Model | MS2 Vertical 9100 |
| Price Range | USD 210,000 – 325,000 (FOB China) |
| Mass Range | m/z 5–1500 |
| Sensitivity (ESI+) | ≥ 500,000:1 (S/N, 100 fg injected on-column, reserpine) |
| Maximum System Pressure | 130 MPa |
| Ionization Sources | Dual-source configuration (e.g., ESI & APCI swappable without venting) |
| Brand | Elite |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Instrument Type | Triple Quadrupole |
| Mass Range | m/z 5–1500 |
| Sensitivity (ESI+) | ≥ 500,000:1 (S/N, 100 fg injected on-column, reserpine) |
| Maximum System Pressure | 130 MPa |
| Ionization Sources | Dual ESI/APCI Interchangeable Source |
| Software Platform | EliteChrom LC-MS Workstation |
| Brand | Elite |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Direct Manufacturer |
| Origin Category | Domestic (China) |
| Model | MS²Vertical 9020 |
| Price Range | USD 140,000 – 255,000 |
| Instrument Type | Tandem Quadrupole (QqQ) |
| Application Scope | General-Purpose |
| Mass Range | m/z 5–3000 amu |
| Maximum LC System Pressure | 1300 bar |
| Brand | Elite |
|---|---|
| Origin | Liaoning, China |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Instrument Type | Triple Quadrupole (QqQ) LC-MS/MS |
| Price Range | USD 140,000 – 255,000 (FOB) |
| Application Scope | General-purpose quantitative and qualitative analysis in regulated and research laboratories |
| Compliance | Designed to support GLP/GMP workflows and 21 CFR Part 11–compliant data integrity requirements |
| Brand | Elite |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Triple Quadrupole (QqQ) |
| Mass Range | m/z 19–2800 |
| Configuration | Integrated LC-MS/MS System |
| Application Scope | General-Purpose Quantitative and Qualitative Analysis |
| Compliance | Designed for GLP/GMP-aligned laboratories |
| Brand | EXPEC / Superspectra |
|---|---|
| Origin | Zhejiang, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | EXPEC 5210 |
| Instrument Type | Triple Quadrupole (QqQ) |
| Application Scope | General-Purpose |
| Mass Range | Not Specified |
| Sensitivity | Not Specified |
| Resolution | Not Specified |
| Mass Accuracy | Not Specified |
| Operating Pressure Range | Not Specified |
| Brand | EXPEC |
|---|---|
| Origin | Zhejiang, China |
| Manufacturer Type | Authorized Distributor |
| Regional Category | Domestic (China) |
| Model | EXPEC 5310 |
| Instrument Type | Triple Quadrupole |
| Application Scope | General-Purpose |
| Brand | Advion Interchim Scientific |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported Instrument |
| Model | iASAP Inert Gas Atmospheric Pressure Solid Analysis Probe |
| Instrument Type | APCI Ion Source |
| Application Scope | General-Purpose |
| Mass Range | 10–2000 m/z |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine) |
| Resolution | 0.5–0.85 m/z (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Compliance | Compatible with Advion expression® CMS and compact CMS platforms |
| Brand | Ion Tec Co., Ltd. |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Instrument Type | Triple Quadrupole (QqQ) LC-MS/MS |
| Mass Range | m/z 15–2000 |
| Sensitivity | ≤0.5 pg on-column injection of reserpine (S/N ≥ 100:1 in MRM mode) |
| Resolution | >2000 (full width at half maximum, FWHM) |
| Brand | Advion |
|---|---|
| Origin | USA |
| Model | TriVersa NanoMate® |
| Instrument Type | Chip-Based Nanoelectrospray Ion Source |
| Mass Range | 100 Da – 100 kDa |
| Sensitivity | Dependent on Coupled Mass Spectrometer |
| Resolution | Dependent on Coupled Mass Spectrometer |
| Accurate Mass Capability | Dependent on Coupled Mass Spectrometer |
| Compliance | ASTM E2915, ISO/IEC 17025 (when operated in GLP/GMP environments), FDA 21 CFR Part 11–ready software architecture |
| Brand | PerkinElmer |
|---|---|
| Origin | Canada |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Status | Imported |
| Model | QSight 400 |
| Instrument Type | Triple Quadrupole (TQ) LC-MS/MS |
| Application Scope | General-Purpose |
| Mass Range | Available upon consultation |
| Sensitivity | Available upon consultation |
| Resolution | Available upon consultation |
| Accurate Mass Capability | Not applicable (unit-mass resolution TQ system) |
| Brand | PerkinElmer |
|---|---|
| Origin | Singapore |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Status | Imported |
| Model | QSight 500 |
| Instrument Type | Triple Quadrupole (TQ) LC/MS/MS |
| Application Scope | General-purpose quantitative and confirmatory analysis in regulated and research laboratories |
| Brand | PerkinElmer |
|---|---|
| Origin | USA |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Category | Imported Instrument |
| Model | QSight |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Application Domain | General-Purpose Quantitative Analysis |
| Ionization Sources | Dual ESI/APCI Configurable |
| Polarity Switching Speed | Microsecond-Level |
| Detection Principle | Electrospray Ionization (ESI) / Atmospheric Pressure Chemical Ionization (APCI) Coupled with Triple Quadrupole Mass Filtering and Collision-Induced Dissociation (CID) |
| Brand | 1124123/13213112 |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Instrument Type | Linear Ion Trap |
| Application Field | General-Purpose |
| Mass Range | m/z 50–1000 |
| Sensitivity | 0.5 ng/mL (for standard test compound under defined LC-MS conditions) |
| Resolution | ≤0.5 Da (FWHM at m/z 500) |
| Dimensions | 33.3 × 23.5 × 14.6 cm |
| Weight | 8.5 kg |
| Battery Life | Up to 2 hours (integrated Li-ion power supply) |
| Vacuum System | Dual-stage non-continuous atmospheric pressure interface (DAPI) with built-in turbomolecular pump |
| Analysis Time | <3 minutes from sample introduction to report-ready output |
| Brand | ASPEC |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Nimbus |
| Instrument Type | Electrospray Ionization (ESI) Source |
| Compatibility | Thermo and SCIEX LC-MS Systems |
| Operating Mode | Standalone (No External PC or Software Required) |
| Key Technology | Integrated eFrit Nanospray Emitters, Dual-Column Switching, On-Chip Column Heating & Temperature Control, Active Spray Tip Purging with Sheath Nitrogen Gas |
| Brand | Reilap |
|---|---|
| Origin | Zhejiang, China |
| Manufacturer Type | Authorized Distributor |
| Regional Classification | Domestic (China) |
| Model | Novisar Apply Series |
| Price Range | USD 140,000 – 280,000 |
| Instrument Type | Triple Quadrupole |
| Application Scope | Specialized |
| Mass Range | 5–2000 amu (extendable to 5–2200 amu) |
| Sensitivity | (1) ESI+, MRM mode: 1 pg reserpine, S/N ≥ 1,200,000:1 (up to 2,000,000:1) |
| (2) ESI−, MRM mode | 1 pg chloramphenicol, S/N ≥ 1,200,000:1 (up to 2,000,000:1) |
| Resolution | 0.4–2 amu |
| Brand | Antec |
|---|---|
| Origin | Netherlands |
| Model | ROXY™ EC |
| Application | Online Electrochemical Cell for LC-MS Coupling |
| Compatibility | Universal MS Interface (Agilent, Thermo Fisher, Waters, SCIEX, Shimadzu) |
| Configuration | Flow-through electrochemical flow cell with integrated electrode cartridge and MS-compatible solvent handling |
| Regulatory Context | Designed for GLP-compliant metabolic stability screening and oxidative stress simulation studies |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | SCIEX 7500+ System |
| Instrument Type | Triple Quadrupole (Tandem Quadrupole, QqQ) |
| Application Scope | Universal LC-MS/MS Analysis |
| MRM Transition Rate | 800 transitions/sec |
| Vacuum System Compatibility | Dry Pump Compatible |
| Regulatory Alignment | Designed for GLP/GMP-compliant laboratories |
| Software Platform | SCIEX OS |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Instrument Type | Tandem Quadrupole Mass Spectrometer |
| Configuration | Acoustic Droplet Ejection (ADE) Coupled to Triple Quadrupole MS |
| Regulatory Design | Designed for GLP/GMP-Compliant Quantitative Bioanalysis |
| Software Compliance | Supports 21 CFR Part 11 Audit Trail and Electronic Signatures |
| Throughput | Up to 3 samples per second |
| Workflow Integration | Direct ADE-to-MS Interface Without Chromatographic Separation |
| Application Focus | High-Throughput Quantitative Screening in Drug Discovery, ADME, and Clinical Biomarker Analysis |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported Instrument |
| Model | Echo™ MS System |
| Pricing | Upon Request |
| Application Scope | General-Purpose High-Throughput Quantitative Analysis |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | Echo™ MS+ System |
| Configuration Options | Integrated with SCIEX Triple Quad™ 6500+ System or ZenoTOF™ 7600 System |
| Sample Introduction Method | Contactless Acoustic Droplet Ejection (ADE) |
| Throughput | Up to 1 sample per second |
| Compatibility | Standard 384-well and 1536-well microplates |
| Interface | Orthogonal Probe Ionization (OPI) Source |
| Regulatory Alignment | Designed for GLP/GMP-compliant workflows |
| Software Platform | SCIEX OS v2.4 or later |
| Brand | SCIEX |
|---|---|
| Origin | Singapore |
| Instrument Type | Tandem Quadrupole (Triple Quad™) or QTRAP® Mass Spectrometer |
| Flow Rate Range | 1–200 µL/min |
| Ion Source | OptiFlow™ Turbo V with Integrated Column Heater (up to 90 °C) |
| Spray Technology | SteadySpray™ Probe with Smart Probe Recognition |
| LC Platform | M5 Microflow LC featuring Microfluidic Flow Control™ |
| Column Compatibility | Phenomenex MicroFlow™ Columns |
| Software | SCIEX OS with MultiQuant™ MRMPilot™ and MasterView™ |
| Regulatory Compliance | FDA 21 CFR Part 11, GLP/GMP-ready audit trail, ISO/IEC 17025-aligned workflows |
| Sample Introduction | Auto-sampler with vial-bottom sensing and jet-wash pump |
| Hardware Interface | Tool-free, hand-tight standard fittings with audible click confirmation |
| Gradient Delivery | Dual-pump architecture supporting direct injection and trap-elute modes |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | QTRAP 4500 System |
| Category | Hybrid Triple Quadrupole / Linear Ion Trap Mass Spectrometer |
| Regulatory Status | Research-Use-Only (RUO), Not FDA-cleared or CE-IVD marked |
| Compliance | Designed for GLP/GMP-compliant laboratories |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | QTRAP® 6500+ |
| Instrument Type | Hybrid Triple Quadrupole/Linear Ion Trap |
| Mass Range | Up to m/z 2,000 |
| Sensitivity | >10× improvement in detection sensitivity |
| Resolution | Unit mass resolution |
| Accurate Mass Capability | Not applicable (non-high-resolution platform) |
| Ionization Sources | IonDrive Turbo V, TurboIonSpray®, APCI, DuoSpray™, NanoSpray® III, SelexION®+ DMS, LDTD, LESA Clarity, Digital PicoView, NanoSource |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | Triple Quad 6500+ |
| Instrument Type | Tandem Quadrupole (QqQ) LC-MS/MS System |
| Mass Range | 2000 m/z |
| Dynamic Range | 6 orders of magnitude |
| Polarity Switching Time | 5 ms |
| Scan Speed | 12,000 Da/sec |
| Ion Sources | IonDrive Turbo V, TurboIonSpray, APCI, DuoSpray, PhotoSpray, NanoSpray III, LDTD, LESA Clarity, Digital PicoView |