Liquid Chromatography Mass Spectrometry
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| Brand | Phytronix |
|---|---|
| Origin | Canada |
| Model | Luxon |
| Instrument Type | Atmospheric Pressure Ion Source |
| Technology | Second-Generation Laser Diode Array Thermal Desorption (LDTD²) |
| Sample Throughput | Up to 30,000+ samples/24h |
| Analysis Time per Sample | ≤ 0.6 s |
| Compatible Plate Formats | 96-well, 384-well, 1536-well LazWell™ microplates |
| Automation Level | Fully Robotic, Unattended Operation |
| MS Compatibility | SCIEX, Thermo Fisher, Waters, Shimadzu triple quadrupole and Q-TOF mass spectrometers |
| Regulatory Alignment | Designed for GLP/GMP-compliant workflows with audit-trail-ready software architecture |
| Ionization Mechanism | Solvent-free, atmospheric-pressure chemical ionization (APCI) via laser-induced rapid thermal desorption |
| Brand | MassTech |
|---|---|
| Origin | USA |
| Model | UHR, HR |
| Instrument Type | Atmospheric Pressure Ion Source |
| Sensitivity | Attomole-level (sub-fmol/µL) |
| Spatial Resolution | <5 µm |
| Mass Range | Determined by Coupled Mass Analyzer |
| Accurate Mass Capability | Dependent on Host Mass Spectrometer |
| Brand | MassTech (ASPEC as authorized distributor) |
|---|---|
| Origin | USA |
| Instrument Type | 3D Ion Trap Mass Spectrometer |
| Model | MT50 |
| Mass Range | 30–2500 amu |
| Sensitivity | 50 pg/µL reserpine, S/N ≥ 10:1 |
| Resolution | 6000 (FWHM at m/z 400) |
| Mass Accuracy | ±0.3 amu |
| Scan Speed | 1000–8000 amu/s or up to 5 spectra/sec |
| Ionization Compatibility | ESI, oESI, 2ndESI, APCI, DART, AP/MALDI |
| Power Input | 90–240 VAC, 50/60 Hz |
| Power Consumption | 250–300 W |
| Dimensions (L×W×H) | 51 × 43 × 30 cm |
| Weight | <35 kg |
| Operating Mode | MS¹ and MSⁿ (up to MS⁵) |
| Polarity | Positive/Negative Switchable |
| Gas Requirement | None (gas-free operation) |
| Transport | Shock-damped wheeled case |
| Brand | PerkinElmer |
|---|---|
| Origin | Canada |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Status | Imported |
| Model | QSight 400 |
| Instrument Type | Triple Quadrupole (TQ) LC-MS/MS |
| Application Scope | General-Purpose |
| Mass Range | Available upon consultation |
| Sensitivity | Available upon consultation |
| Resolution | Available upon consultation |
| Accurate Mass Capability | Not applicable (unit-mass resolution TQ system) |
| Brand | PerkinElmer |
|---|---|
| Origin | Singapore |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Status | Imported |
| Model | QSight 500 |
| Instrument Type | Triple Quadrupole (TQ) LC/MS/MS |
| Application Scope | General-purpose quantitative and confirmatory analysis in regulated and research laboratories |
| Brand | PerkinElmer |
|---|---|
| Origin | USA |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Category | Imported Instrument |
| Model | QSight |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Application Domain | General-Purpose Quantitative Analysis |
| Ionization Sources | Dual ESI/APCI Configurable |
| Polarity Switching Speed | Microsecond-Level |
| Detection Principle | Electrospray Ionization (ESI) / Atmospheric Pressure Chemical Ionization (APCI) Coupled with Triple Quadrupole Mass Filtering and Collision-Induced Dissociation (CID) |
| Brand | Phytronix |
|---|---|
| Origin | Canada |
| Model | LDTD, Luxon |
| Instrument Type | Ion Source |
| Sample Introduction Speed | ≤6 s (LDTD), ≤1 s (Luxon), 0.6 s (Luxon-1536) |
| Ionization Mode | Atmospheric Pressure Chemical Ionization (APCI) via Laser-Induced Thermal Desorption |
| Compatibility | Triple Quadrupole (QqQ), Ion Trap, TOF, Q-TOF, Orbitrap, and Hybrid MS Platforms (SCIEX, Thermo Fisher, Shimadzu, Waters) |
| Sample Format | 96-well, 384-well, 1536-well plates (barcoded LazWell™ plates) |
| Carrier Gas | Zero-air (≤3 ppm H₂O) or dried air with VOC scrubber |
| Laser Source | Infrared laser diode array, 20 W max output, power ramp 0–45% in 3 s, hold at 45% for ~2 s, then rapid decay to 0% |
| Sample Volume | 0.5–10 µL (depending on plate format) |
| Residual Carryover | None (no memory effect) |
| Regulatory Compliance | Fully compatible with GLP/GMP workflows |
| Environmental Impact | Solvent-free, column-free, pump-free operation — eliminates LC consumables (mobile phases, columns, tubing, vials, filters) |
| Brand | 1124123/13213112 |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Instrument Type | Linear Ion Trap |
| Application Field | General-Purpose |
| Mass Range | m/z 50–1000 |
| Sensitivity | 0.5 ng/mL (for standard test compound under defined LC-MS conditions) |
| Resolution | ≤0.5 Da (FWHM at m/z 500) |
| Dimensions | 33.3 × 23.5 × 14.6 cm |
| Weight | 8.5 kg |
| Battery Life | Up to 2 hours (integrated Li-ion power supply) |
| Vacuum System | Dual-stage non-continuous atmospheric pressure interface (DAPI) with built-in turbomolecular pump |
| Analysis Time | <3 minutes from sample introduction to report-ready output |
| Brand | ASPEC |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Nimbus |
| Instrument Type | Electrospray Ionization (ESI) Source |
| Compatibility | Thermo and SCIEX LC-MS Systems |
| Operating Mode | Standalone (No External PC or Software Required) |
| Key Technology | Integrated eFrit Nanospray Emitters, Dual-Column Switching, On-Chip Column Heating & Temperature Control, Active Spray Tip Purging with Sheath Nitrogen Gas |
| Brand | Reilap |
|---|---|
| Origin | Zhejiang, China |
| Manufacturer Type | Authorized Distributor |
| Regional Classification | Domestic (China) |
| Model | Novisar Apply Series |
| Price Range | USD 140,000 – 280,000 |
| Instrument Type | Triple Quadrupole |
| Application Scope | Specialized |
| Mass Range | 5–2000 amu (extendable to 5–2200 amu) |
| Sensitivity | (1) ESI+, MRM mode: 1 pg reserpine, S/N ≥ 1,200,000:1 (up to 2,000,000:1) |
| (2) ESI−, MRM mode | 1 pg chloramphenicol, S/N ≥ 1,200,000:1 (up to 2,000,000:1) |
| Resolution | 0.4–2 amu |
| Brand | Antec |
|---|---|
| Origin | Netherlands |
| Model | ROXY™ EC |
| Application | Online Electrochemical Cell for LC-MS Coupling |
| Compatibility | Universal MS Interface (Agilent, Thermo Fisher, Waters, SCIEX, Shimadzu) |
| Configuration | Flow-through electrochemical flow cell with integrated electrode cartridge and MS-compatible solvent handling |
| Regulatory Context | Designed for GLP-compliant metabolic stability screening and oxidative stress simulation studies |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | SCIEX 7500+ System |
| Instrument Type | Triple Quadrupole (Tandem Quadrupole, QqQ) |
| Application Scope | Universal LC-MS/MS Analysis |
| MRM Transition Rate | 800 transitions/sec |
| Vacuum System Compatibility | Dry Pump Compatible |
| Regulatory Alignment | Designed for GLP/GMP-compliant laboratories |
| Software Platform | SCIEX OS |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | AB API 4000 |
| Instrument Type | Triple Quadrupole (QqQ) with Linear Accelerator (LINAC) Collision Cell |
| Mass Range | 10–3000 Da |
| Sensitivity | S/N ≥ 100:1 for 1 pg on-column reserpine (ESI+) |
| Resolution | 0.5–0.7 Da (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Ionization Sources | TurboIonSpray® and APCI® (plug-and-play interchangeable probes) |
| Vacuum System | Dual-stage air-cooled turbomolecular pumps |
| Dimensions (H×D×L) | 52 × 50 × 130 cm |
| Operating Environment | 15–30 °C, 208–240 V AC, High-Purity Nitrogen & Zero-Air |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Mass Range | 10–3000 m/z |
| Sensitivity | S/N ≥ 100:1 (for reserpine, ESI+) |
| Resolution | Full Width at Half Maximum (FWHM) 0.5–0.7 m/z |
| Mass Accuracy | ±0.1 Da (internal calibration) |
| Configuration | Used / Refurbished System with HPLC Integration Capability |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | AB-4000 |
| Instrument Type | Triple Quadrupole (QqQ) |
| Mass Range | 5–2,000 m/z |
| Sensitivity | <10 fg on-column for reserpine (ESI+, 400 µL/min) |
| Resolution | Unit mass resolution (±0.13 u at full width at half maximum) |
| Accurate Mass Capability | ±0.13 u (calibrated, external standard) |
| Ionization Sources | Turbo V™ ESI/APCI dual-mode source with rapid switchable probe |
| Collision Cell | Linear Accelerator (LINAC™) collision cell |
| Detector | Digital Pulse Detection System with >5-decade dynamic range |
| Software | Analyst® 1.7.2 or later (21 CFR Part 11 compliant) |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | API 3000 |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Mass Range | 10–3000 Da |
| Sensitivity | S/N ≥ 100:1 for 1 pg on-column reserpine (ESI+) |
| Resolution | 0.5–0.7 Da (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Ion Sources | Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI) |
| Operating Temperature | 15–30 °C |
| Power Supply | 208–240 V AC, 50/60 Hz |
| Required Gases | High-purity nitrogen (≥99.999%), zero-air (oil-free, particle-filtered compressed air) |
| Vacuum System | Varian DS602 dual-stage rotary vane pump with oil mist filter |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | API 4000 Q-Trap |
| Instrument Type | Triple Quadrupole Linear Ion Trap Hybrid |
| Mass Range | 5–2000 m/z |
| Sensitivity | <10 fg on-column for SRM (e.g., reserpine) |
| Resolution | Unit mass resolution (0.7 Da full width at half maximum) |
| Accurate Mass Capability | Not applicable (nominal mass instrument) |
| Ion Source Options | TurboIonSpray® and APCI® with plug-and-play interchangeability |
| Collision Cell | LINAC™ high-efficiency linear accelerator collision cell |
| Detection System | Pulse-counting electron multiplier |
| Dynamic Range | 1–4 × 10⁶ cps |
| Vacuum System | Dual-stage turbomolecular pumps with air-cooled design |
| Operating Temperature | 15–30 °C |
| Power Supply | 208–240 V AC, 50/60 Hz |
| Required Gases | High-purity nitrogen (≥99.999%), zero-air (oil-free, particle-free compressed air) |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | API 4000 |
| Instrument Type | Tandem Quadrupole (QqQ) |
| Ionization Modes | Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI) |
| Software Platform | Analyst® 1.6.3 or later |
| Regulatory Compliance | Designed for GLP/GMP environments |
| Mass Range | m/z 5–3,000 (typical operational range) |
| Sensitivity | Sub-femtogram on-column detection for selected pharmaceutical compounds (e.g., ≤5 fg on-column for midazolam in MRM mode) |
| Resolution | Unit mass resolution (0.7 Da full width at half maximum, FWHM) |
| Mass Accuracy | ±0.2 Da (calibrated) |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | API4000 Q-Trap |
| Instrument Type | Hybrid Triple Quadrupole/Linear Ion Trap Mass Spectrometer |
| Mass Range | 5–2,000 m/z |
| Sensitivity | <10 fg on-column for reserpine (MRM, ESI+) |
| Resolution | Unit mass resolution in Q1 and Q3 |
| Mass Accuracy | ±0.2 Da (calibrated) |
| Scan Speed | Up to 6,000 Da/sec |
| Dynamic Range | 4 orders of magnitude (1–4 × 10⁶ cps) |
| Vacuum System | Dual-stage air-cooled turbomolecular pumps |
| Operating Temperature | 15–30 °C |
| Power Supply | 208–240 V AC, 50/60 Hz |
| Required Gases | High-purity nitrogen (≥99.999%), zero-air (oil-free, particle- and hydrocarbon-free compressed air) |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Instrument Type | Tandem Quadrupole Mass Spectrometer |
| Configuration | Acoustic Droplet Ejection (ADE) Coupled to Triple Quadrupole MS |
| Regulatory Design | Designed for GLP/GMP-Compliant Quantitative Bioanalysis |
| Software Compliance | Supports 21 CFR Part 11 Audit Trail and Electronic Signatures |
| Throughput | Up to 3 samples per second |
| Workflow Integration | Direct ADE-to-MS Interface Without Chromatographic Separation |
| Application Focus | High-Throughput Quantitative Screening in Drug Discovery, ADME, and Clinical Biomarker Analysis |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported Instrument |
| Model | Echo™ MS System |
| Pricing | Upon Request |
| Application Scope | General-Purpose High-Throughput Quantitative Analysis |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | Echo™ MS+ System |
| Configuration Options | Integrated with SCIEX Triple Quad™ 6500+ System or ZenoTOF™ 7600 System |
| Sample Introduction Method | Contactless Acoustic Droplet Ejection (ADE) |
| Throughput | Up to 1 sample per second |
| Compatibility | Standard 384-well and 1536-well microplates |
| Interface | Orthogonal Probe Ionization (OPI) Source |
| Regulatory Alignment | Designed for GLP/GMP-compliant workflows |
| Software Platform | SCIEX OS v2.4 or later |
| Brand | SCIEX |
|---|---|
| Origin | Singapore |
| Instrument Type | Tandem Quadrupole (Triple Quad™) or QTRAP® Mass Spectrometer |
| Flow Rate Range | 1–200 µL/min |
| Ion Source | OptiFlow™ Turbo V with Integrated Column Heater (up to 90 °C) |
| Spray Technology | SteadySpray™ Probe with Smart Probe Recognition |
| LC Platform | M5 Microflow LC featuring Microfluidic Flow Control™ |
| Column Compatibility | Phenomenex MicroFlow™ Columns |
| Software | SCIEX OS with MultiQuant™ MRMPilot™ and MasterView™ |
| Regulatory Compliance | FDA 21 CFR Part 11, GLP/GMP-ready audit trail, ISO/IEC 17025-aligned workflows |
| Sample Introduction | Auto-sampler with vial-bottom sensing and jet-wash pump |
| Hardware Interface | Tool-free, hand-tight standard fittings with audible click confirmation |
| Gradient Delivery | Dual-pump architecture supporting direct injection and trap-elute modes |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | QTRAP 4500 System |
| Category | Hybrid Triple Quadrupole / Linear Ion Trap Mass Spectrometer |
| Regulatory Status | Research-Use-Only (RUO), Not FDA-cleared or CE-IVD marked |
| Compliance | Designed for GLP/GMP-compliant laboratories |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Instrument Type | Triple Quadrupole with Linear Ion Trap (QTRAP®) |
| Model | 6500+ |
| Mass Range | 10–2000 m/z |
| Sensitivity | ≥100:1 S/N (for 1 pg µL⁻¹ reserpine, ESI positive mode, MRM) |
| Resolution | Full width at half maximum (FWHM) ≤0.5 Da (unit resolution) |
| Mass Accuracy | ≤0.1 Da (internal calibration) |
| Maximum Source Pressure | 12,000 Pa (≈90 Torr) |
| Scan Speed | ≥20,000 Da/sec (MRM transition speed) |
| Ionization Sources | Dual ESI/APCI, IonDrive™ Turbo V™ Source |
| Collision Cell | LINAC™-optimized RF-only collision cell |
| Detector | IonDrive™ High-Energy Detector+ |
| Software Platform | SCIEX OS v2.4 or later with Scheduled MRM™ Algorithm, MultiQuant™ MX for Quantitation, and MasterView™ for Data Review |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | QTRAP® 6500+ |
| Instrument Type | Hybrid Triple Quadrupole/Linear Ion Trap |
| Mass Range | Up to m/z 2,000 |
| Sensitivity | >10× improvement in detection sensitivity |
| Resolution | Unit mass resolution |
| Accurate Mass Capability | Not applicable (non-high-resolution platform) |
| Ionization Sources | IonDrive Turbo V, TurboIonSpray®, APCI, DuoSpray™, NanoSpray® III, SelexION®+ DMS, LDTD, LESA Clarity, Digital PicoView, NanoSource |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | SCIEX 5500 |
| Instrument Type | Triple Quadrupole Mass Spectrometer |
| Configuration | Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) |
| Mass Range | m/z 5–2000 (typical for QqQ operation) |
| Polarity Switching Speed | ≤ 50 ms |
| MRM Dwell Time | down to 1 ms |
| Ion Source Options | Turbo V™, DuoSpray™, PhotoSpray™ |
| Ion Guide | QJet™ 2 Collision Cell |
| Software Platform | Analyst® 1.7.1 or later |
| Regulatory Compliance | Designed for 21 CFR Part 11–compliant workflows (audit trail, electronic signatures, user access control) |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | Triple Quad 6500+ |
| Instrument Type | Tandem Quadrupole (QqQ) LC-MS/MS System |
| Mass Range | 2000 m/z |
| Dynamic Range | 6 orders of magnitude |
| Polarity Switching Time | 5 ms |
| Scan Speed | 12,000 Da/sec |
| Ion Sources | IonDrive Turbo V, TurboIonSpray, APCI, DuoSpray, PhotoSpray, NanoSpray III, LDTD, LESA Clarity, Digital PicoView |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | SCIEX Triple Quad 7500 LC-MS/MS System |
| Instrument Type | Tandem Quadrupole (Triple Quadrupole) Mass Spectrometer |
| Configuration | LC-MS/MS with QTRAP® Ready Architecture |
| Application Scope | Universal Quantitative and Qualitative Analysis in Life Sciences, Clinical Research, Environmental, Food Safety, and Forensic Laboratories |
| Regulatory Compliance | Designed for GLP/GMP-compliant environments |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | Triple Quad™ 3500 |
| Configuration | ESI/APCI Turbo V™ Ion Source |
| Collision Cell | Curved LINAC™ |
| Regulatory Compliance | Designed for GLP/GMP and FDA 21 CFR Part 11–ready workflows (software-dependent) |
| Application Scope | Small-molecule quantitation in pharmaceutical, clinical research, forensic, food safety, and environmental laboratories |