Liquid Chromatography Mass Spectrometry
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| Brand | Waters |
|---|---|
| Origin | USA |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Model | TQD |
| Configuration | Integrated UPLC/MS/MS System |
| Ionization Options | Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI) |
| Mass Range | 50–1200 m/z |
| Typical MRM Sensitivity | <10 fg on-column for reserpine (S/N ≥ 20:1) |
| Scan Speed | Up to 8,000 Da/sec in MRM mode |
| Collision Cell | T-Wave™ RF-only quadrupole collision cell |
| Data Acquisition Rate | ≥20 MRM transitions/sec |
| Software Platform | MassLynx v4.1 with TargetLynx, QuanLynx, QCMonitor, RADAR, TrendPlot, InliStart, and Quanpedia modules |
| Compliance | Fully compatible with 21 CFR Part 11 audit trail requirements and GLP/GMP workflows |
| Brand | Waters |
|---|---|
| Origin | United Kingdom |
| Instrument Type | Quadrupole-Time-of-Flight (Q-TOF) |
| Model | Xevo G3 QTof |
| Application Scope | Universal LC-MS/MS Platform |
| Mass Range | Not specified in source data |
| Resolution | Not specified in source data |
| Mass Accuracy | Not specified in source data |
| Sensitivity | Not specified in source data |
| Pressure Range | Not specified in source data |
| Compliance Context | Designed for GLP/GMP-aligned laboratories |
| Brand | Waters |
|---|---|
| Origin | United Kingdom |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Xevo MRT |
| Instrument Type | Time-of-Flight (TOF) |
| Application Scope | General-Purpose |
| Resolution | 100,000 FWHM at 100 Hz |
| Mass Accuracy | <500 ppb |
| m/z Range | Broad, consistent across full scan range |
| Analyzer Architecture | Multi-Reflecting Time-of-Flight (MRT) with 4-meter effective flight path and 8 reflections |
| Brand | Waters |
|---|---|
| Origin | United Kingdom |
| Model | Xevo TQ Absolute |
| Instrument Type | Triple Quadrupole (TQ) |
| Application Scope | Universal LC-MS/MS Quantitation |
| Mass Range | Not specified by manufacturer in public datasheets |
| Sensitivity | Up to 15× higher for challenging negative-ion-mode analytes vs. prior-generation TQ systems |
| Resolution | Unit mass resolution standard for SRM/MRM transitions |
| Mass Accuracy | Not specified (typical for QqQ: ±0.1–0.2 Da under routine conditions) |
| Operating Pressure Range | Vacuum system maintained at <1×10⁻⁶ mbar in analyzer region |
| Brand | Waters |
|---|---|
| Origin | United Kingdom |
| Model | Xevo TQ Absolute XR |
| Instrument Type | Tandem Quadrupole (Triple Quadrupole) |
| Application Scope | Universal LC-MS/MS Analysis |
| Mass Range | Not Specified by Manufacturer |
| Sensitivity | Not Specified by Manufacturer |
| Resolution | Not Specified by Manufacturer |
| Mass Accuracy | Not Specified by Manufacturer |
| Operating Pressure Range | Not Specified by Manufacturer |
| Brand | Waters |
|---|---|
| Origin | United Kingdom |
| Instrument Type | Tandem Quadrupole (Triple Quad) |
| Model | Xevo TQ-S cronos |
| Configuration | LC-MS/MS System |
| Detection Principle | Electrospray Ionization (ESI) / Atmospheric Pressure Chemical Ionization (APCI) coupled with tandem mass spectrometry in Multiple Reaction Monitoring (MRM) mode |
| MRM Transition Rate | Up to 555 transitions per second |
| Linear Dynamic Range | >5 orders of magnitude |
| Typical Precision | <4% RSD for challenging analytes with 5 ms dwell time |
| Regulatory Compliance Support | 21 CFR Part 11, GLP/GMP audit trails, ISO/IEC 17025-aligned workflows |
| Brand | Waters |
|---|---|
| Origin | United Kingdom |
| Instrument Type | Tandem Quadrupole (QqQ) |
| Model | Xevo TQ-S micro |
| Ion Sources Compatibility | ESI, APCI, ESCi, UniSpray, APGC, ionKey/MS, ASAP, Nanoflow ESI |
| LC Compatibility | ACQUITY UPLC H-Class PLUS/Bio PLUS, I-Class PLUS, UPC2, M-Class |
| Key Technology | Z-Spray Ion Source, StepWave Off-Axis Ion Focusing |
| Regulatory Alignment | Compliant with SANTE/11813/2017, FDA 21 CFR Part 11 (via MassLynx software), GLP/GMP data integrity requirements |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Xevo TQ-S |
| Instrument Type | Tandem Quadrupole Mass Spectrometer |
| Ionization Compatibility | Electrospray Ionization (ESI), Atmospheric Pressure Chemical Ionization (APCI), and Optional Sources (e.g., ESCi, UniSpray) |
| Key Technology | StepWave™ Ion Optics, ScanWave™ Collision Cell, RADAR™ Acquisition Mode |
| Regulatory Alignment | Designed for GLP/GMP environments |
| Brand | Waters |
|---|---|
| Origin | USA |
| Instrument Type | Triple Quadrupole LC-MS/MS |
| Model | Xevo TQ-S |
| Configuration | Refurbished System with Full Functional Validation |
| Ionization Compatibility | Electrospray (ESI), Atmospheric Pressure Chemical Ionization (APCI), and Optional Sources (e.g., APPI, ESCi) |
| Mass Analyzer Architecture | Three Sequential Quadrupole Stages (Q1 → Collision Cell → Q3) |
| Scan Modes | MRM, Full Scan, Product Ion Scan, Precursor Ion Scan, Neutral Loss Scan, Selected Reaction Monitoring (SRM), RADAR™ Simultaneous Quantitation & Screening |
| Software Platform | MassLynx v4.2 or Later with TargetLynx XS, QuanLynx, and UNIFI Integration Capabilities |
| Regulatory Compliance Support | 21 CFR Part 11 Audit Trail, Electronic Signatures, GLP/GMP Data Integrity Framework |
| Brand | Waters |
|---|---|
| Origin | USA |
| Instrument Type | Tandem Quadrupole (QqQ) |
| Model | Xevo TQ-S |
| Ionization Flexibility | Universal Source Architecture |
| Key Technology | StepWave™ Ion Guide, T-Wave™ Collision Cell, RADAR™ Simultaneous Quant/Qual Mode |
| Software Suite | MassLynx™, TargetLynx™, QCMonitor™, IntelliStart™, Quanpedia™ |
| Regulatory Support | 21 CFR Part 11 compliant workflows, GLP/GMP-ready audit trails, ISO/IEC 17025-aligned data integrity framework |
| Brand | Waters |
|---|---|
| Origin | United Kingdom |
| Model | Xevo TQ-XS |
| Instrument Type | Tandem Quadrupole (Triple Quad) |
| Ionization Source Compatibility | UniSpray™, Electrospray Ionization (ESI), Atmospheric Pressure Chemical Ionization (APCI) |
| Detection Principle | Selected Reaction Monitoring (SRM) / Multiple Reaction Monitoring (MRM) |
| Dynamic Range | 6 orders of magnitude (Xtended Dynamic Range, XDR™) |
| Ion Transmission Technology | StepWave XS™ off-axis ion optics |
| Probe Design | Tool-free atmospheric pressure ionization (API) source |
| Software Platform | MassLynx™ NX, TargetLynx XS™, Intellistart™, QUANPEDIA™ |
| Regulatory Compliance Support | 21 CFR Part 11, GLP/GMP audit trails, electronic signatures |
| Brand | Waters |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | TQ-XS |
| Instrument Type | Triple Quadrupole |
| Application Field | General-Purpose |
| Mass Range | 10–2,000 m/z |
| Sensitivity | <100 fg on-column for typical pharmaceutical compounds (e.g., verapamil) |
| Resolution | Full Width at Half Maximum (FWHM) ≤ 0.5 Da |
| Mass Accuracy | ≤ 0.1 Da (internal calibration) |
| Operating Pressure Range | Up to 1200 bar (LC front-end compatible) |
| Brand | Waters |
|---|---|
| Origin | USA |
| Instrument Type | Tandem Quadrupole (QqQ) LC-MS/MS |
| Model | Xevo TQD |
| Mass Range | 10–3000 m/z |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, ESI+) |
| Resolution | 0.5–0.7 m/z (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Configuration | Includes UPLC Binary Solvent Manager, Sample Manager, Sample Organizer, CH-A Column Heater, E2M28 Vacuum Pump, SB-C18 Column (50 mm × 2.1 mm, 1.8 µm), MassLynx Software Suite (InliStart, Quanpedia, QCMonitor, TargetLynx, TrendPlot), and RADAR™ Acquisition Mode |
| Brand | Waters |
|---|---|
| Origin | USA |
| Model | Xevo TQD |
| Instrument Type | Tandem Quadrupole (QqQ) |
| Mass Range | 10–3000 Da |
| Sensitivity | S/N ≥ 100:1 (1 pg reserpine, ESI+) |
| Resolution | 0.5–0.7 Da (FWHM) |
| Mass Accuracy | ±0.1 Da |
| Brand | Waters |
|---|---|
| Origin | USA |
| Instrument Type | Tandem Quadrupole (QqQ) |
| Model | Xevo TQD |
| Ionization Flexibility | Universal Source Architecture Supporting ESI, APCI, ESCi, and Optional Atmospheric Pressure Photoionization (APPI) |
| Chromatographic Compatibility | Optimized for UPLC and HPLC Coupling |
| Data Acquisition Speed | High-speed MRM acquisition supporting sub-3-second UPLC peaks |
| Software Suite | MassLynx v4.2 with IntelliStart, Quanpedia, QCMonitor, TargetLynx, TrendPlot, and RADAR™ Mode |
| Regulatory Compliance Support | 21 CFR Part 11–compliant audit trails, electronic signatures, and GLP/GMP-ready workflow tools |
| Hardware Architecture | Robust RF-only quadrupole design with T-Wave collision cell for enhanced ion transmission and fragmentation efficiency |
| Brand | WAYEAL |
|---|---|
| Origin | Anhui, China |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Country of Origin | China |
| Model | TQ9200 |
| Instrument Type | Triple Quadrupole (Tandem QqQ) Mass Spectrometer |
| Application Scope | Universal (Broad-Spectrum Quantitative & Qualitative Analysis) |
| LC Component | WAYEAL LC3600 Ultra-High-Performance Liquid Chromatograph |
| Ionization Source | Electrospray Ionization (ESI), Standard Configuration |
| Vacuum Interface | High-Durability Conical Interface with Active Desolvation |
| Detection Mode | Multiple Reaction Monitoring (MRM), Selected Reaction Monitoring (SRM), Full Scan, Product Ion Scan, Precursor Ion Scan, Neutral Loss Scan |
