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| Brand | Ahram |
|---|---|
| Origin | South Korea |
| Model | S1 / S1e |
| Instrument Type | Real-Time Fluorescent Quantitative PCR System |
| Sample Throughput | 24-well |
| Heating Mechanism | Tri-zone semiconductor thermal blocks with micro-tube angular oscillation |
| Cycle Time | ≤10 min for 30 cycles |
| Power Options | Rechargeable Li-ion battery (≥4 h continuous operation) or AC adapter |
| Dimensions (W×D×H) | 19.5 × 17.7 × 17.9 cm |
| Weight | 3.0 kg (3.8 kg with battery) |
| Detection Channels | 3 / 5 / 6 multiplex fluorescent channels |
| Connectivity | LAN, Wi-Fi, Bluetooth, USB, optional GPS |
| Control Interface | Integrated capacitive touchscreen OS |
| Compliance | Designed to support GLP/GMP-aligned workflows |
| Brand | Unchained Labs |
|---|---|
| Origin | USA |
| Model | Leprechaun |
| Application | Single-particle immuno-structural analysis of lentiviral vectors and extracellular vesicles (e.g., exosomes) |
| Detection Principle | Fluorescence-based single-particle imaging coupled with antibody- and probe-mediated orthogonal labeling |
| Sensitivity | ≥1 × 10⁷ particles/mL |
| Particle Sizing Range | ~30–200 nm (diameter) |
| Capture Flexibility | Compatible with anti-VSV-G, anti-gp70, or user-provided custom capture antibodies |
| Nucleic Acid Detection | RNA-specific fluorescent probes (e.g., Quasar 670-labeled oligos) |
| Structural Discrimination | Simultaneous detection of capsid protein (e.g., p24), envelope glycoprotein (e.g., VSV-G), and genomic RNA |
| Aggregation Assessment | Quantitative resolution of monodisperse virions vs. dimers, trimers, and higher-order aggregates |
| Regulatory Alignment | Designed to support process development under ICH Q5A(R2), USP <1043>, and FDA CMC guidance for gene therapy products |
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