BIO-DL Auto-Stripper for Microplate Seals
| Brand | BIO-DL |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Domestic (China) |
| Model | Auto-Stripper |
| Pricing | Available Upon Request |
Overview
The BIO-DL Auto-Stripper for Microplate Seals is an electromechanically actuated, benchtop automation device engineered to reliably and consistently remove adhesive sealing films—such as aluminum, foil, or polymer-based heat seals—from standard 96-well and 384-well microplates. It operates on a precision-controlled linear stripping principle: a calibrated peeling head engages the seal edge at a defined angle and peel force, then advances along the plate perimeter under closed-loop position feedback. This eliminates manual handling variability while preserving well integrity and minimizing aerosol generation—a critical requirement in high-throughput screening (HTS), ELISA, qPCR, and cell-based assay workflows where cross-contamination and operator fatigue must be rigorously controlled.
Key Features
- Single-button operation with tactile feedback and LED status indication—no programming or calibration required for routine use.
- Tool-free plate loading compatible with ANSI/SLAS-compliant microplates (including skirted, semi-skirted, and unskirted formats) and common seal types (aluminum foil, PCR-grade polypropylene film, pressure-sensitive acrylic adhesives).
- Fail-safe mechanical design with no rotating blades, springs, or friction-driven rollers—reducing wear-related drift and eliminating seal fragmentation or residue deposition.
- Dual-mode functionality: standalone manual mode for lab-scale operations; TTL-triggered and RS-232–enabled integration mode for synchronization with liquid handlers, stackers, or robotic arms (e.g., Hamilton STAR, Tecan Freedom EVO, Agilent Bravo).
- CE-marked enclosure with IP20-rated electrical safety and low-noise DC motor drive (<55 dB(A) at 1 m), suitable for ISO Class 7 cleanroom-adjacent environments.
Sample Compatibility & Compliance
The Auto-Stripper accommodates microplates conforming to ANSI SLAS-1-2019 and ANSI SLAS-4-2019 dimensional standards. It has been validated for consistent seal removal across plates from Corning, Greiner Bio-One, Sarstedt, Thermo Fisher Scientific, and Nunc—with no observable well deformation or seal re-adhesion after stripping. The system complies with IEC 61000-6-2 (immunity) and IEC 61000-6-4 (emissions), and its operational log records timestamped strip events for GLP-aligned documentation. While not FDA 21 CFR Part 11–certified out-of-the-box, audit trails generated via optional software integration support traceability requirements under ISO/IEC 17025 and GMP Annex 11 frameworks.
Software & Data Management
The device supports basic serial communication (RS-232, 9600 baud, 8N1) for external command triggering and status polling. Optional firmware upgrade enables CSV-formatted event logging (timestamp, plate ID, seal type flag, error code) via USB-C interface. When integrated into LIMS or MES platforms, strip events can be mapped to sample IDs using standardized HL7 or ASTM E1384 message schemas. No proprietary cloud service or vendor-hosted platform is required—data remains fully under institutional control. Firmware updates are delivered as signed binary packages with SHA-256 checksums for integrity verification.
Applications
- Pre-PCR plate preparation in molecular diagnostics labs, ensuring uniform seal removal prior to thermal cycling without disturbing reaction mixtures.
- Automated ELISA workflow integration—enabling unattended transition from incubation to wash/read steps in regulated clinical testing environments.
- Cell-based assay platforms where repeated manual seal removal introduces variability in evaporation rates and edge effects across replicate plates.
- Biobanking operations requiring chain-of-custody–aligned plate processing prior to cryogenic storage or aliquoting.
- Contract research organizations (CROs) performing method transfer studies, where inter-operator consistency in plate handling directly impacts assay robustness metrics (e.g., CV% of controls, Z′-factor stability).
FAQ
Does the Auto-Stripper support 1536-well plates?
No—it is dimensionally optimized for 96-well and 384-well formats per ANSI/SLAS specifications. Plates exceeding 127.76 mm × 85.48 mm footprint are not supported.
Can it remove dried-down or aged adhesive seals?
Yes—validation testing confirms reliable stripping of seals stored up to 12 months at ambient conditions, provided no delamination or oxidation of the adhesive layer has occurred.
Is maintenance required beyond routine cleaning?
Only periodic inspection of the peeling head’s PTFE-coated contact surface and wipe-down with 70% isopropanol is recommended; no lubrication or recalibration is necessary within the specified 50,000-cycle service life.
What safety certifications does it hold?
CE marking per Machinery Directive 2006/42/EC and EMC Directive 2014/30/EU; RoHS 2011/65/EU compliant; electrical safety tested to IEC 61010-1:2010.
