Chu Ding Technology HSC-12B Circular Water Bath Nitrogen Evaporator

Overview

The Chu Ding Technology HSC-12B Circular Water Bath Nitrogen Evaporator is a precision-engineered instrument designed for gentle, reproducible concentration and solvent removal from multiple liquid samples simultaneously. It operates on the principle of controlled nitrogen gas sweeping across the surface of heated samples—accelerating solvent evaporation while minimizing thermal degradation of thermolabile analytes. Unlike dry-block evaporators, the HSC-12B employs a uniform water bath heating system that ensures exceptional temperature homogeneity (±0.5 °C at 40–100 °C), critical for quantitative recovery in applications such as pesticide residue analysis, pharmaceutical impurity profiling, and environmental contaminant quantification. Its circular configuration accommodates standard 12 × 16 mm or 12 × 18 mm test tubes, vials, or culture tubes, with adjustable gas needle height to match varying vessel heights—enabling consistent gas delivery regardless of sample volume or container geometry.

Key Features

• Uniform circular water bath with corrosion-resistant 316 stainless steel tank and integrated digital PID temperature controller for stable, repeatable heating across all 12 positions
• Dual LED digital display showing both setpoint and real-time bath temperature, with programmable over-temperature cutoff (adjustable up to 105 °C)
• Independent gas flow regulation per channel via precision needle valves; total flow range: 0–5 L/min with calibrated rotameter
• Height-adjustable gas distribution manifold mounted on linear guide rails—enables precise alignment of nitrogen needles 5–30 mm above liquid surface
• All wetted components—including gas manifolds, needle guides, and bath interior—constructed from 316 stainless steel or anodized aluminum with epoxy-polyester coating for long-term chemical resistance
• Compact footprint (280 × 280 × 320 mm) and low power draw (150 W) suitable for benchtop deployment in QC labs, forensic units, and academic research facilities

Sample Compatibility & Compliance

The HSC-12B supports common sample containers including 10–15 mL glass test tubes, 16 mm OD × 100 mm culture tubes, and 18 mm OD GC vials. Tube holders are non-fixed—allowing manual positioning to accommodate irregular or oversized vessels. The unit is engineered to meet core requirements for method validation under ISO/IEC 17025-accredited laboratories: temperature stability is verified per ASTM E2234 (Standard Practice for Calibration of Laboratory Equipment), and gas flow consistency conforms to USP guidelines for residual solvent testing. While not inherently 21 CFR Part 11 compliant, its operational parameters (temperature logs, run duration, gas flow settings) can be manually recorded in laboratory notebooks or integrated into LIMS-compatible workflows for full auditability in GMP/GLP environments.

Software & Data Management

The HSC-12B operates as a stand-alone analog-digital hybrid instrument without embedded firmware or network connectivity. All control and monitoring are performed locally via front-panel interface. However, its deterministic behavior—stable temperature ramping, repeatable gas flow profiles, and mechanical adjustability—makes it highly compatible with external data logging systems. Users may integrate optional PT100 probes and USB-connected data loggers (e.g., Omega OM-DAQPRO-5300) to capture time-stamped temperature and flow metadata for SOP documentation. For regulated environments, this enables generation of ALCOA+–compliant records when paired with validated electronic lab notebooks (ELNs) or chromatography data systems (CDS).

Applications

• Routine concentration of extracts prior to GC-MS or LC-MS/MS analysis in environmental testing (e.g., PAHs in soil leachates, PFAS in wastewater)
• Preparative cleanup steps in pharmacopeial methods (USP , EP 2.4.24) for residual solvent determination in APIs
• High-throughput sample prep in forensic toxicology labs processing blood, urine, or hair extracts for benzodiazepine or opioid screening
• Stabilization of unstable metabolites during clinical biomarker discovery workflows requiring low-thermal-stress evaporation
• QC release testing in contract manufacturing organizations (CMOs) where batch-to-batch reproducibility of evaporation rate must be documented per ICH Q5C

FAQ

What is the maximum operating temperature of the water bath?
The HSC-12B is rated for continuous operation up to 100 °C; the over-temperature safety cutoff is factory-set at 105 °C and user-adjustable within ±5 °C.
Can I use organic solvents directly in the water bath?
No. The bath medium must be deionized water, 10% glycerol/water mixtures, or silicone oil (for temperatures >100 °C). Direct solvent immersion risks corrosion, vapor ignition, and calibration drift.
Is the nitrogen gas manifold compatible with inert gas generators?
Yes—the inlet accepts standard 6 mm OD polyurethane or stainless steel tubing with 1/8″ NPT threading; compatibility confirmed with Parker Hannifin and Peak Scientific nitrogen generators.
How often should the water bath be cleaned and refilled?
Daily visual inspection is recommended; full drain, descaling (with 5% citric acid solution), and refill required every 72 hours of cumulative operation to prevent mineral buildup and microbial growth.
Does the unit include tube holders or adapters?
It ships with a universal circular aluminum support plate featuring 12 × Ø16 mm recessed holes; optional adapter inserts for Ø13 mm, Ø18 mm, and Ø21 mm tubes are available under part numbers HSC-ADP-13, HSC-ADP-18, and HSC-ADP-21.