Cole-Parmer 75900-05 Single-Channel Programmable Syringe Pump
| Brand | Cole-Parmer |
|---|---|
| Origin | USA |
| Model | 75900-05 |
| Operating Modes | Infuse/Withdraw |
| Flow Rate Range | 0.73 µL/h to 2100 mL/h |
| Accuracy | ±1% |
| Repeatability | ±1% |
| Max Syringe Capacity | 60 mL |
| Max Plunger Speed | 5.1 cm/h |
| Linear Force at Minimum Speed | 13.5 kg |
| Dimensions (L×W×H) | 24 × 12 × 11 cm |
| Power Supply | 240 V, 50 Hz |
| Compliance | CE-marked |
| Interface | RS232 serial control |
| Software Capability | Up to 100 pumps controllable simultaneously |
| Programmable Units | µL/h, µL/min, mL/h, mL/min |
| Advanced Functions | Pre-fill volume, repeat dispensing, user-defined alarm triggers |
Overview
The Cole-Parmer 75900-05 Single-Channel Programmable Syringe Pump is an electromechanically actuated precision fluid delivery system engineered for reproducible, low-to-moderate flow rate applications in analytical chemistry, pharmaceutical development, microfluidics, and laboratory-scale process control. Utilizing a high-resolution stepper motor coupled with precision-machined gear reduction and optical encoder feedback, the pump delivers volumetric accuracy through direct plunger displacement—eliminating reliance on tubing elasticity or compressibility as in peristaltic systems. Its bidirectional infuse/withdraw capability supports closed-loop experimental protocols such as titration, reagent addition with back-flush, or sample dilution series. Designed for integration into automated workflows, the device maintains operational state—including flow rate, volume delivered, and direction—across power cycles, ensuring continuity in unattended overnight or multi-day experiments.
Key Features
- Microprocessor-controlled stepper motor with gear-reduction drive ensures consistent torque delivery across the full speed range, enabling stable low-flow operation down to 0.73 µL/h.
- RS232 serial interface compliant with standard ASCII command protocol, supporting seamless integration with LabVIEW, MATLAB, Python-based control environments, or custom SCADA systems.
- Onboard memory retains all user-configured parameters (flow rate, target volume, direction, pre-fill volume, repeat count) after power interruption—no manual reinitialization required.
- Real-time parameter adjustment during active operation: flow rate, direction, and remaining volume may be modified without stopping the pump.
- Programmable alarm conditions include end-of-volume detection, occlusion sensing (via motor current monitoring), and user-defined volume thresholds—critical for GLP-compliant documentation.
- Supports syringes from 0.5 mL to 60 mL capacity; compatible with glass, plastic, and stainless-steel barrels meeting ISO 7886-1 dimensional tolerances.
Sample Compatibility & Compliance
The 75900-05 accommodates a broad range of chemically resistant syringes, including polypropylene, borosilicate glass, and PTFE-coated variants, making it suitable for aqueous, organic, and mildly corrosive media. It does not require tubing or fluid-path wetted parts beyond the syringe barrel and plunger seal—minimizing carryover and simplifying cleaning validation. The unit bears CE marking per Directive 2014/30/EU (EMC) and 2014/35/EU (LVD), confirming conformity with essential health and safety requirements for electrical equipment within the European Economic Area. While not intrinsically rated for hazardous locations, its robust chassis and isolated power supply support use in ISO Class 5–8 cleanrooms when paired with appropriate syringe sterilization protocols.
Software & Data Management
Cole-Parmer provides optional PC software (compatible with Windows 7–11) that enables centralized configuration, real-time monitoring, and synchronized multi-pump operation—up to 100 units on a single RS232 daisy-chain or via USB-to-serial adapter. The software logs timestamped event records (start/stop, direction change, alarm trigger, volume completion) in CSV format for audit trail generation. For regulated environments, the system supports 21 CFR Part 11-compliant workflows when deployed with validated third-party electronic lab notebook (ELN) platforms or LIMS integrations—provided user authentication, audit logging, and electronic signature controls are externally implemented per organizational SOPs.
Applications
- Controlled reagent addition in kinetic studies and reaction calorimetry
- Automated sample introduction for HPLC, ICP-MS, and flow injection analysis (FIA)
- Cell culture media perfusion and nutrient gradient generation in organ-on-chip systems
- Calibration standard preparation with traceable volumetric delivery
- Pharmaceutical dissolution testing requiring precise sink condition maintenance
- Environmental water analysis where low-flow, pulseless delivery minimizes particulate disturbance
FAQ
Is the 75900-05 compatible with third-party syringes?
Yes—any syringe conforming to ISO 7886-1 nominal dimensions and plunger stop geometry can be used, though Cole-Parmer recommends verifying seal compatibility for aggressive solvents.
Does the pump support analog input/output for external triggering?
No—the 75900-05 relies exclusively on RS232 digital communication; analog I/O functionality requires external PLC interfacing via TTL-level signals.
Can flow rate be calibrated against a gravimetric standard?
Yes—users may perform two-point calibration using certified weights and timed collection, with correction factors stored in non-volatile memory for subsequent runs.
What maintenance is required for long-term reliability?
Annual inspection of lead screw lubrication and plunger alignment is recommended; no scheduled replacement of motor or encoder components is specified under normal operating conditions.
Is firmware upgrade capability available?
Firmware updates are provided by Cole-Parmer upon request and installed via RS232 using proprietary utility software—no field-upgradable bootloader is embedded.
