Cole-Parmer Model 33400 Digital Mass Flow Meter
| Brand | Cole-Parmer |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Imported |
| Model | 33400-00 |
| Flow Principle | Differential Pressure-Based Thermal Mass Flow Measurement |
| Accuracy | ±1% of full scale (linearity included) at STP |
| Temperature Coefficient | ±0.15%/°C of full scale |
| Pressure Coefficient | ±0.01% of full scale/psi |
| Repeatability | ±0.25% of full scale |
| Maximum Pressure Drop | 0.18 psid |
| Response Time | 2 s (typical, 25–100% FS to ±2% of actual flow) |
| Operating Temperature | 5–50 °C (41–122 °F) |
| Max System Pressure | 500 psig (34.5 bar) |
| Leak Rate | ≤1 × 10⁻⁹ mL/sec He |
| Power Supply | 11–26 VDC |
| Analog Outputs | 0–5 VDC or 4–20 mA (user-selectable via jumper) |
| Digital Interfaces | RS-232 and RS-485 |
| Process Connection | 1/4" compression fitting |
| Housing Material | Aluminum (standard) |
Overview
The Cole-Parmer Model 33400 Digital Mass Flow Meter is a high-stability, microprocessor-controlled thermal mass flow instrument engineered for precise measurement and control of clean, non-corrosive gases in laboratory, pilot-scale, and light industrial applications. Unlike volumetric flowmeters, this device employs a differential pressure-based thermal sensing principle—combining constant-temperature anemometry with integrated pressure and temperature compensation—to deliver true mass flow readings independent of upstream gas composition variations (within calibrated gas sets). Its architecture is optimized for long-term stability under dynamic process conditions, with built-in self-diagnostic routines and automatic zero-point drift correction triggered only during confirmed no-flow states. The meter operates across a wide range of standard flow spans—from 0–5 sccm to 0–10 LPM—with full-scale accuracy maintained per NIST-traceable calibration protocols.
Key Features
- Non-volatile memory storing up to 10 user-defined gas calibration tables and conversion coefficients for 32 distinct gases—including N₂, O₂, CO, CO₂, H₂, Ar, He, and custom blends
- Configurable engineering units: supports 23 pre-programmed mass/volumetric units (e.g., sccm, slm, g/min) plus user-defined units via digital command
- Dual analog output selection: jumper-configurable 0–5 VDC or 4–20 mA, compliant with standard PLC and DCS input modules
- Two programmable relay outputs with adjustable delay (0–3600 s) and lockout mode—enabling fail-safe alarm activation for high/low flow excursions
- Integrated flow accumulator with time-weighted totalization; real-time calculation of cumulative mass flow based on instantaneous rate and elapsed time
- Backlit LCD display showing simultaneous primary flow rate, accumulated total, and diagnostic status (e.g., CPU temperature, auto-zero status, communication health)
- RS-232 and RS-485 interfaces supporting Modbus RTU protocol for remote configuration, data logging, and firmware interrogation without physical access
- Dynamic response compensation and linearization table adjustment accessible via serial command—allowing field optimization for specific piping configurations or pulsation profiles
Sample Compatibility & Compliance
This instrument is validated exclusively for use with dry, particle-free, non-condensing, chemically inert gases. It is not rated for liquids, aerosols, vapors, or corrosive media (e.g., Cl₂, NH₃, H₂S). All units ship with a manufacturer-provided NIST-traceable calibration certificate (certified per ISO/IEC 17025:2017), documenting as-delivered performance against reference standards at defined STP conditions (0 °C, 101.325 kPa). While not intrinsically safe or explosion-proof, the device complies with CE marking requirements for electromagnetic compatibility (EN 61326-1) and low-voltage directive (2014/35/EU). Its firmware architecture supports audit-ready parameter change logs—facilitating GLP/GMP-aligned validation when deployed in regulated environments such as pharmaceutical R&D or medical gas system commissioning.
Software & Data Management
No proprietary PC software is required for basic operation; all configuration and interrogation are executed via ASCII command sets over RS-232/RS-485. Supported commands include reading/writing gas tables, adjusting K-factors, setting alarm thresholds, initiating auto-zero cycles, and exporting internal diagnostics (e.g., sensor resistance, ambient temperature, supply voltage). For integration into SCADA or LIMS platforms, the meter responds to standard Modbus function codes (03h, 06h, 10h) with register-mapped parameters. All configuration changes are stored in EEPROM with write-cycle endurance exceeding 100,000 operations. Critical operational parameters—including flow span, gas selection, and output scaling—are protected by optional password-enabled write-lock to prevent inadvertent modification during routine operation.
Applications
- Gas blending and ratio control in analytical instrumentation (e.g., carrier gas delivery for GC, purge gas for ICP-MS)
- Mass flow verification in environmental chamber conditioning systems and controlled-atmosphere gloveboxes
- Leak testing support—monitoring steady-state purge flows or detecting deviations indicative of system integrity loss
- Calibration transfer between primary standards and working standards in metrology labs
- Process gas monitoring in semiconductor tool purging, plasma etch exhaust management, and fuel cell test benches
- Research-scale bioreactor sparging control where oxygen or nitrogen mass delivery must be tightly regulated
FAQ
Does the Model 33400 require periodic recalibration?
Yes—while the unit maintains long-term stability, Cole-Parmer recommends annual recalibration against traceable standards to ensure continued compliance with ±1% FS accuracy specifications, particularly when used in quality-critical workflows.
Can the same unit measure multiple gases without hardware changes?
Yes—the embedded non-volatile memory allows storage and rapid switching between up to 10 preloaded gas calibrations, each with its own thermal conductivity and specific heat compensation profile.
Is the auto-zero function fully automatic or operator-initiated?
Auto-zero is initiated manually via digital command but executes autonomously only when the internal flow sensor confirms zero flow for ≥5 seconds and ambient temperature remains stable within ±0.5 °C.
What is the maximum allowable upstream pressure for accurate operation?
The device is rated for continuous operation at system pressures up to 500 psig; however, accuracy specifications assume pressure compensation is enabled and upstream regulators maintain stable supply pressure within ±10% of setpoint.
Are firmware updates available, and how are they applied?
Firmware revisions are released periodically to enhance communication robustness and diagnostic depth; updates are delivered as HEX files and installed via RS-232 using Cole-Parmer’s documented bootloader sequence—no hardware modification required.

