Drick DRK-Z640 LED Cold Light Source Automatic Polarimeter with True-Color Touchscreen
| Brand | Drick |
|---|---|
| Origin | Shandong, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | DRK-Z640 |
| Price Range | USD 11,200–14,000 (FOB Qingdao) |
| Product Type | Automatic Polarimeter |
| Temperature Control | Integrated Peltier-based Thermostatic Cell Holder (±0.1 °C stability) |
| Digital Display | High-Resolution 7-inch Capacitive Touchscreen (800×480) |
| Light Source | Stable 589.3 nm LED (Na-D line equivalent, >10,000 h lifetime) |
| Measurement Range | Optical Rotation ±89.99° |
| Accuracy | ±0.01° (for –45° ≤ α ≤ +45°) |
| Repeatability | ≤0.002° (RSD < 0.05% at 10° standard quartz control) |
Overview
The Drick DRK-Z640 is a high-precision automatic polarimeter engineered for quantitative chiral analysis in pharmaceutical quality control, fine chemical synthesis validation, food & beverage sugar content certification, and academic research laboratories. It operates on the fundamental principle of optical rotation—measuring the angular deflection of plane-polarized light as it passes through an optically active medium—using a temperature-stabilized measurement cell and a narrow-band 589.3 nm LED source calibrated to sodium D-line spectral equivalence. Unlike traditional lamp-based instruments, the DRK-Z640 eliminates warm-up drift and spectral instability, delivering consistent baseline performance across extended operation cycles. Its closed-loop Peltier thermostatic system maintains sample cell temperature within ±0.1 °C over ambient fluctuations, ensuring compliance with pharmacopeial requirements for temperature-controlled polarimetric assays (e.g., USP , EP 2.2.7, and ChP IV).
Key Features
- True-color 7-inch capacitive touchscreen interface with intuitive icon-driven navigation and multilingual OS support (English, Spanish, French, Chinese)
- Integrated Peltier temperature control module (range: 10–40 °C), programmable in 0.1 °C increments with real-time monitoring and auto-compensation algorithms
- High-stability 589.3 nm LED light source offering >10,000 hours operational life, zero warm-up delay, and minimal intensity decay (<0.5% per 1,000 h)
- Dual-mode measurement capability: optical rotation (α, in degrees) and sucrose scale (°Z), with automatic unit conversion and calibration traceability
- Robust mechanical architecture featuring precision-ground stainless-steel optical path housing, anti-vibration base plate, and sealed photodetector assembly
- Compliance-ready design: supports audit trail generation, user access levels (admin/operator), and electronic signature functionality aligned with FDA 21 CFR Part 11 principles
Sample Compatibility & Compliance
The DRK-Z640 accommodates standard 100 mm, 200 mm, and custom-length sample cells (including jacketed thermostatic cells), with optional 2 mL micro-cells for precious or low-volume samples. It meets ISO/IEC 17025:2017 metrological traceability requirements when calibrated using NIST-traceable quartz control plates (–45°, 0°, +45°). Instrument validation documentation includes IQ/OQ protocols, linearity verification reports (per ASTM E1252), and temperature uniformity mapping. The system satisfies GLP/GMP environmental monitoring criteria for routine QC labs and supports full data integrity workflows required under EU Annex 11 and ICH Q5C.
Software & Data Management
Embedded firmware enables local data storage (≥10,000 measurements), CSV export via USB port, and optional Ethernet/Wi-Fi connectivity for LIMS integration. The included PC software (DRK-PolSoft v3.2) provides advanced reporting tools—including trend analysis, statistical process control (SPC) charts, batch comparison overlays, and automated certificate-of-analysis (CoA) generation. All raw measurement logs include timestamp, operator ID, cell ID, temperature reading, and instrument serial number—enabling full forensic reconstruction during regulatory audits. Data encryption (AES-128) and role-based access controls ensure confidentiality and integrity per HIPAA and GDPR standards.
Applications
- Pharmaceutical QC: Enantiomeric purity verification of APIs (e.g., ibuprofen, levodopa), excipient identity testing, and stability-indicating assay development
- Food & Beverage: Sucrose concentration determination in syrups, honey, fruit juices, and soft drinks per AOAC 951.02 and ICUMSA methods
- Chemical Manufacturing: Real-time monitoring of asymmetric synthesis reactions, chiral catalyst performance evaluation, and batch release testing
- Academic Research: Kinetic studies of racemization/epimerization, solvent polarity effects on specific rotation, and polymer helicity characterization
- Biotechnology: Quantification of optically active biomolecules including amino acids, peptides, carbohydrates, and nucleosides
FAQ
What is the wavelength accuracy and spectral bandwidth of the LED source?
The DRK-Z640 utilizes a stabilized 589.3 nm LED with center wavelength tolerance ±0.2 nm and FWHM ≤2.5 nm, certified against NIST SRM 2034 reference filters.
Does the instrument support multi-point calibration and linearity verification?
Yes—built-in calibration routines accept up to five reference points using quartz control plates or certified sucrose solutions; linearity error remains ≤±0.005° across full ±89.99° range.
Can the DRK-Z640 be integrated into a laboratory network for centralized data management?
It supports TCP/IP communication, OPC UA protocol, and direct SQL database push (via optional DRK-Link Gateway), enabling seamless connection to ELN, LIMS, or MES platforms.
Is temperature-controlled measurement mandatory, or can ambient mode be used?
Ambient mode is available; however, temperature-controlled operation is required for pharmacopeial compliance and reproducible results in regulated environments.
What documentation is provided for regulatory submissions?
Factory-issued Certificate of Conformance, calibration report (traceable to NIST), IQ/OQ validation templates, and 21 CFR Part 11 readiness checklist are included with each unit.
