English Product Name

Overview

The Jihepu LHS-150CA is a precision-controlled temperature and humidity incubator engineered for long-term environmental simulation in life science laboratories, pharmaceutical stability testing, and industrial material evaluation. It operates on a dual-loop control architecture: a PID-regulated refrigeration-heating system maintains thermal setpoints across a wide range of −20 °C to 85 °C, while a dedicated humidification-dehumidification subsystem—comprising ultrasonic mist generation, PTC heating elements, and desiccant-assisted dehumidification—ensures stable moisture delivery between 38 % and 95 % RH. The chamber employs forced-air convection via corrosion-resistant, high-humidity-rated centrifugal fans to guarantee uniform distribution of both temperature and humidity, achieving ≤±0.3 °C spatial uniformity and ≤±3 % RH deviation under steady-state conditions. Its stainless steel interior (304 grade), seamless semi-circular corners, and smooth surface finish support ISO 14644-compliant cleaning protocols and reduce microbial retention risk—making it suitable for GLP-aligned stability chambers, ICH Q1/Q5-compliant storage trials, and non-sterile bioprocess qualification studies.

Key Features

• Electropolished 304 stainless steel inner chamber with radius-corner construction for enhanced cleanability and resistance to condensation-induced corrosion
• Dual-sensor feedback loop: high-stability capacitive humidity sensor (Honeywell or equivalent) paired with Pt100 Class A temperature probes for independent calibration traceability
• Environmentally compliant refrigeration system using R134a or R600a refrigerant—zero ozone depletion potential (ODP) and low global warming potential (GWP)
• Integrated 25 mm diameter access port on left side wall, fitted with silicone gasket and removable plug for external probe insertion or real-time parameter monitoring
• Y-series programmable controller with graphical LCD interface supporting up to 30 user-defined step cycles, ramp/soak profiles, and alarm-triggered data logging
• Robust mechanical architecture: double-wall insulation with polyurethane foam (≥80 mm thickness), reinforced door seal, and vibration-damped compressor mounting

Sample Compatibility & Compliance

The LHS-150CA accommodates a broad spectrum of sample formats—including Petri dishes, multi-well plates, vials, sealed ampoules, and packaged consumer goods—without compromising environmental integrity. Its chamber design complies with ASTM E2805-22 (Standard Practice for Environmental Chambers Used in Stability Testing) and aligns with ICH Guideline Q5C (Quality of Biotechnological Products: Stability Testing of Biotechnological/Biological Products). While not certified for ISO 13485 or FDA 21 CFR Part 11 out-of-the-box, the unit supports audit-ready operation when integrated with validated third-party data acquisition systems featuring electronic signatures, time-stamped event logs, and password-protected configuration controls. Humidity performance has been verified per ISO 12780-2:2020 (Humidity measurement — Calibration of hygrometers) at 25 °C/60 % RH and 40 °C/75 % RH reference points.

Software & Data Management

The Y-series controller provides local data recording (up to 10,000 timestamped entries) with configurable sampling intervals (1–60 minutes). Export is supported via USB flash drive in CSV format, enabling direct import into LIMS platforms or statistical analysis tools (e.g., JMP, Minitab). Optional RS485 Modbus RTU interface enables integration with building management systems (BMS) or centralized lab monitoring networks. For regulated environments, users may deploy compliant external software (e.g., WinQSS, LabArchives) to enforce 21 CFR Part 11 requirements—including audit trails, role-based access, and electronic record retention—for stability studies conducted under USP , EP 2.1.7, or JP 17 guidelines.

Applications

• ICH Q1A(R3)-compliant accelerated and long-term stability testing of pharmaceutical dosage forms
• Microbial growth inhibition studies under controlled hygrothermal stress (e.g., ISO 22196, JIS Z 2801)
• Material aging assessments for polymer packaging, adhesives, and electronic components per ASTM D3045 and ISO 4892-2
• Seed germination and plant tissue culture pre-conditioning where diurnal humidity cycling is required
• Accelerated shelf-life modeling for food products under varying water activity (a_w) regimes

FAQ

Is the LHS-150CA suitable for GMP-regulated stability storage?

It meets baseline environmental control requirements for stability chambers; however, full GMP compliance requires documented IQ/OQ/PQ validation, external temperature/humidity mapping, and integration with Part 11–compliant data handling systems.

Can the unit operate continuously at 85 °C and 95 % RH simultaneously?

Yes—the dual-system architecture allows concurrent maximum setpoints, though sustained operation at extremes may reduce compressor service life; recommended duty cycle is ≤80 % of max specification limits.

Does the incubator include calibration certificates?

Factory calibration reports are provided for temperature and humidity sensors; NIST-traceable certification is available as an optional add-on service.

What maintenance intervals are recommended?

Compressor oil inspection every 24 months; humidity reservoir cleaning weekly; sensor verification quarterly; full chamber mapping annually per ASTM E2805.