EURPING Q720 Laboratory Bottle Washer

Overview

The EURPING Q720 Laboratory Bottle Washer is an industrial-grade, programmable cleaning system engineered for high-throughput, reproducible decontamination of glassware and labware in regulated pharmaceutical, biotechnology, and contract research organizations (CROs). It operates on a validated thermal cleaning principle—combining precisely controlled temperature cycles, adjustable hydrodynamic pressure, and multi-stage rinse-dry sequences—to remove organic residues, particulates, and trace contaminants in accordance with EN ISO 15883-1:2012 (Medical washing disinfectors) and aligned practices for laboratory equipment cleaning validation per ICH Q5A, USP , and FDA guidance on analytical instrument qualification. Designed for continuous operation in GMP environments, the Q720 has demonstrated sustained reliability under 12-hour daily duty cycles across multiple Tier-1 CDMOs—including WuXi AppTec, Hengrui Medicine, SGS, Huahai Pharmaceutical, Asymchem, Shanghai Pharmaceuticals, and Humanwell Healthcare—with zero field returns over five years.

Key Features

• Microprocessor-based control system with 7-inch full-color touchscreen interface, supporting three-tier password access and integration with laboratory LIMS via RS232 serial communication.
• Preloaded library of 30 standardized wash programs and 120 user-definable protocols—each assigned a unique alphanumeric code and fully parameterized (temperature ramping, dwell time, flow rate, detergent dosing, drying profile).
• Top-fed dual-layer spray manifold architecture: water enters from the chamber ceiling and distributes radially through a 12-way symmetrical splitter; all nozzles on the same rack layer deliver uniform jet height and orifice diameter, ensuring ≤10% pressure deviation across the wash zone.
• Soft-start variable-frequency drive (VFD) for the main circulation pump, enabling stepless regulation of flow rate from 0 to 600 L/min—critical for protecting delicate plasticware while delivering high-pressure rinsing for heavily soiled chromatography vials or volumetric flasks.
• Integrated “Black Box” event logger: continuously records operational status of all electronic components (relays, solenoids, temperature sensors, pump motors, door interlocks), timestamped and exportable for audit trail compliance under 21 CFR Part 11 and GLP/GMP requirements.
• Dual-mode drying system: forced hot-air injection directly into vessel interiors via dedicated ducting; adjustable drying temperature (ambient to 120 °C) and duration (0–300 min); minimum air throughput: 110 m³/h.
• Comprehensive safety architecture: electromagnetic door lock with mechanical backup, dry-run protection, low-detergent level alarm, real-time leak detection, automatic drain filtration, recirculating water pre-filtration, and power-loss state retention with auto-resume capability.

Sample Compatibility & Compliance

The Q720 accommodates up to 460 standard 2-mL HPLC vials or 100 pieces of 10–250 mL volumetric flasks per cycle (dual-layer loading). Its vertical, gravity-aligned pipette cleaning module eliminates dead zones in bulb-type transfer pipettes—a design improvement over angled wash systems. All wetted surfaces are constructed from ASTM A240 316L stainless steel (chamber interior) and 304 stainless steel (outer casing), ensuring corrosion resistance against acidic and alkaline detergents. The unit carries CE marking and complies with EN 61000-6-2/6-4 (EMC), EN 61000-3-2/3-3 (harmonics), and EN 60335-1 (safety). EURPING’s quality management system is certified to ISO 9001:2015 and ISO 14001:2015.

Software & Data Management

The embedded control firmware supports raw data export via RS232 to external PCs or printers, generating time-stamped PDF or CSV reports containing cycle ID, start/end timestamps, temperature profiles, pump duty cycles, detergent consumption logs, and fault codes. Audit-trail functionality meets ALCOA+ principles: attributable, legible, contemporaneous, original, accurate, complete, consistent, enduring, and available. Optional OPC UA or Modbus TCP gateway modules enable seamless connectivity to enterprise MES or SCADA platforms.

Applications

The Q720 is routinely deployed in QC/QA laboratories for cleaning sample vials prior to GC/MS or LC-MS analysis; sterilization of volumetric glassware used in assay preparation; removal of residual APIs from reaction vessels in API development labs; and routine decontamination of pipettes, centrifuge tubes, and culture flasks in cell biology workflows. Its validated cleaning performance supports cleaning validation studies required by regulatory submissions under EMA CHMP/Q5A and FDA Chemistry, Manufacturing, and Controls (CMC) guidelines.

FAQ

Does the Q720 meet EN ISO 15883 standards for washer-disinfectors?

Yes—the thermal cleaning process, temperature uniformity, and cycle documentation capabilities align with EN ISO 15883-1:2012 Annex B for laboratory-grade cleaning validation.
Can the machine be integrated into a centralized LIMS or MES environment?

Yes—via RS232 serial output (standard) or optional OPC UA/Modbus TCP interfaces.
What materials are in contact with wash solution during operation?

All fluid-path components—including chamber, spray arms, pumps, and piping—are fabricated from 316L stainless steel per ASTM A240.
Is drying performance validated for moisture-sensitive applications?

Drying parameters (temperature, airflow, duration) are fully configurable and can be qualified per user-defined acceptance criteria using calibrated hygrometers and residual moisture testing (e.g., Karl Fischer titration).
How is maintenance access designed for serviceability?

Front-access service panels, modular pump assemblies, and tool-free filter housing enable rapid component replacement without specialized tools or chamber disassembly.