HePu EU-K2-D Series Ultra-Pure Water System
| Brand | HePu (Jinan Hepu) |
|---|---|
| Origin | Shandong, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | EU-K2-D |
| Price | USD 4,750 (approx.) |
| Feed Water | RO water, distilled water or deionized water |
| Resistivity | 18.2 MΩ·cm @ 25°C |
| Heavy Metals & Soluble Silica | ≤0.1 ppb |
| Total Organic Carbon (TOC) | <3 ppb |
| Microbial Count | <0.1 CFU/mL |
| Endotoxin | <0.001 EU/mL |
| Particles (>0.1 µm) | <1 particle/mL |
| UV Lamp | Dual-wavelength (254 nm & 185 nm), lifespan ≥8,000 h |
| Final Filtration | 0.22 µm PES membrane |
| Ultrafiltration | MWCO 5,000 Da |
| Power Supply | 220 V, 50 Hz, 50–80 W |
| Dimensions (W×D×H) | 260 × 500 × 520 mm |
Overview
The HePu EU-K2-D Series Ultra-Pure Water System is a high-performance, modular laboratory water purification platform engineered for consistent production of Type I ultrapure water per ISO 3696:1987, ASTM D1193-20, and GB/T 6682–2008 Class I specifications. Designed to accept pre-purified feed water—including reverse osmosis (RO), distilled, or deionized water—the system employs a multi-stage purification architecture integrating dual-wavelength UV photooxidation (254 nm + 185 nm), mixed-bed ion exchange, 5,000 Da molecular weight cutoff ultrafiltration, and terminal 0.22 µm polyethersulfone (PES) filtration. This configuration ensures removal of ionic contaminants, organic compounds, nucleases (RNase/DNase), endotoxins (pyrogens), microorganisms, and sub-micron particles—enabling compliance with stringent requirements for molecular biology, HPLC, LC-MS, cell culture, and trace elemental analysis applications.
Key Features
- Full-color capacitive touchscreen interface with animated real-time system status visualization and intuitive navigation.
- Dual-channel conductivity and resistivity monitoring for both feed water and product water, enabling proactive consumable management and quality assurance.
- Precision dispensing modes: qualitative (fixed resistivity threshold), quantitative (programmable volume), and time-based delivery—supporting volumetric accuracy within ±2% across 1–2 L/min flow range.
- Integrated consumable lifecycle tracking: UV lamp, ion exchange resin, UF module, and final filter lifetimes are user-configurable; remaining service life displayed in hours/days with audible alert and on-screen replacement prompt upon expiration.
- Automated full-loop sanitization protocol with chemical dosing capability, validated for microbial load reduction across entire distribution path—from storage reservoir to point-of-use.
- Continuous recirculation mode maintains ultrapure water quality within the loop, minimizing stagnation-related biofilm formation and particulate accumulation.
- NSF-certified quick-connect fluidic architecture using FDA-compliant tubing and fittings; all wetted surfaces constructed from non-leaching, low-extractable materials (e.g., PES, PVDF, EPDM).
- Low-voltage isolated power design (SELV compliant) and IPX4-rated enclosure ensure safe operation in humid laboratory environments.
- Multi-level access control with password protection and role-based permissions (administrator, operator, viewer) aligned with GLP/GMP documentation integrity requirements.
Sample Compatibility & Compliance
The EU-K2-D series delivers water meeting or exceeding international standards for analytical-grade ultrapure water: resistivity ≥18.2 MΩ·cm at 25°C, TOC <3 ppb, endotoxin <0.001 EU/mL, total viable count <0.1 CFU/mL, and particle count 0.1 µm). Its performance is validated against ISO 3696, ASTM D1193 Type I, CLSI (formerly NCCLS) EP21-A, and CAP Laboratory Accreditation Program criteria. The system’s nuclease-free output (<0.01 ng/mL RNase, <4 pg/mL DNase) supports sensitive applications including qPCR, CRISPR workflows, and primary cell expansion. All consumables—including the 5,000 Da ultrafilter and 0.22 µm PES membrane—are certified free of detectable endotoxins and extractables per USP and .
Software & Data Management
Embedded firmware logs all operational parameters—including timestamped conductivity/resistivity values, UV intensity, flow rate, cumulative volume dispensed, alarm events, and consumable usage—into internal flash memory with ≥12 months of retention capacity. Data export is supported via USB Host interface for regulatory review: historical alarms, calibration records, maintenance logs, and user activity traces comply with FDA 21 CFR Part 11 audit trail requirements when configured with electronic signature functionality. Optional cloud-connected firmware enables remote monitoring through secure web portal or native iOS/Android application—providing real-time status alerts, predictive maintenance notifications, and centralized fleet management for multi-unit installations.
Applications
This system serves as a critical infrastructure component in core research and quality control laboratories where water purity directly impacts assay fidelity. Key use cases include: preparation of mobile phases for UHPLC and LC-MS; dilution standards for ICP-MS and atomic absorption spectroscopy; reagent formulation for ELISA, Western blotting, and immunohistochemistry; media and buffer preparation for mammalian and stem cell culture; and rinsing of precision optics and semiconductor wafers. Its endotoxin- and nuclease-free output makes it suitable for functional genomics, single-cell sequencing library prep, and therapeutic protein manufacturing under cGMP conditions.
FAQ
What feed water quality is required for optimal EU-K2-D performance?
RO water with conductivity <5 µS/cm, or distilled/deionized water meeting ASTM D1193 Type II specifications is recommended. Feed pressure must be maintained between 0–3.0 kg/cm² and temperature within 5–45°C.
Can the system be integrated into existing lab water networks?
Yes—the EU-K2-D features standard 1/4″ push-to-connect ports compatible with common laboratory tubing; optional wall-mount brackets and vertical riser kits facilitate integration with central distribution loops.
Is third-party validation support available for IQ/OQ/PQ protocols?
HePu provides comprehensive validation documentation packages—including test scripts, acceptance criteria, and blank execution records—aligned with ISO/IEC 17025 and GAMP5 guidelines. On-site qualification assistance is available upon request.
How often must consumables be replaced under typical usage?
Under continuous operation at 20 L/h average demand, the mixed-bed cartridge lasts ~6–12 months, UV lamp ≥8,000 h (~12 months), UF module 12–24 months, and final 0.22 µm filter 3–6 months—subject to feed water quality and usage frequency.
Does the system meet cybersecurity requirements for networked labs?
Firmware v3.2+ includes TLS 1.2 encryption, configurable firewall rules, and session timeout controls—supporting compliance with NIST SP 800-53 Rev. 4 AC-17 and ISO/IEC 27001 Annex A.8.2.3 for secure remote access.
