Herexi HR/T16MM Micro High-Speed Refrigerated Centrifuge for African Swine Fever (ASF) Diagnostic Applications

Overview

The Herexi HR/T16MM Micro High-Speed Refrigerated Centrifuge is an engineered solution for nucleic acid and pathogen isolation workflows in biosafety-sensitive diagnostic applications—particularly African Swine Fever (ASF) virus detection. Designed around the principles of high-RCF sedimentation kinetics and thermally stabilized rotor dynamics, this benchtop centrifuge delivers precise, reproducible separation of low-volume biological samples (0.2–2.0 mL) under strictly controlled thermal conditions. Its core architecture integrates a brushless AC frequency-controlled motor, a hermetically sealed refrigeration loop using R404a, and a vibration-damped mechanical platform optimized for continuous operation in high-throughput veterinary diagnostic laboratories. The device complies with ISO 13485:2016 requirements for in vitro diagnostic (IVD) medical device manufacturing and supports GLP-aligned sample processing protocols where temperature stability, rotor integrity, and aerosol containment are non-negotiable.

Key Features

• Brushless AC inverter motor with rapid acceleration/deceleration (≤25 s full ramp-up), delivering stable rotational performance at up to 16,500 rpm and 18,780 × g RCF.
• Environmentally compliant refrigeration system utilizing R404a refrigerant and a non-CFC compressor, enabling programmable temperature control from −20 °C to +40 °C with ±1 °C accuracy; includes pre-cool and standby cooling functions.
• Airtight biocontainment angular rotors featuring integrated silicone gaskets certified to EU RoHS Directive 2015/863, preventing aerosol leakage during high-speed pelleting of ASF-positive swab or serum samples.
• TFT-LCD color touchscreen with dual input mode (touch + physical keys), real-time display of setpoints and actual values (speed, RCF, temperature, time), and on-the-fly parameter adjustment without rotor stoppage.
• Triple-stage damping system—comprising rubber-isolated base mount, asymmetric counterweight balancing, and proprietary composite shock absorbers—ensures minimal vibration transmission and prevents resuspension of delicate viral pellets.
• Full stainless-steel 304 centrifuge chamber, powder-coated steel housing, reinforced front panel, and three-layer structural shielding meet IEC 61010-2-020 safety standards for laboratory equipment.
• Intelligent door lock mechanism with silent electromechanical actuation; auto-engages upon lid closure and interlocks during operation to prevent accidental opening.
• 20 programmable user protocols with recall memory (default startup loads last-used method); 10 independent acceleration and deceleration profiles for gradient-sensitive separations.

Sample Compatibility & Compliance

The HR/T16MM accommodates standard microcentrifuge formats including 0.2 mL PCR strips (2×8 and 4×8 configurations), 1.5 mL and 2.0 mL conical tubes, and 12- or 24-position angular rotors—all fabricated from aerospace-grade forged aluminum for fatigue resistance and thermal uniformity. Its airtight rotor design meets WHO-recommended biosafety level 2 (BSL-2) containment criteria for handling ASFV-infected specimens. Regulatory documentation includes CFDA registration and manufacturing licenses, ISO 9001:2015 quality management certification, and ISO 13485:2016 compliance for IVD-related production processes. The unit satisfies essential requirements of EN 61010-1 and EN 61010-2-020 for electrical safety and mechanical robustness in clinical laboratory environments.

Software & Data Management

While the HR/T16MM operates via embedded firmware without external PC dependency, its interface supports audit-ready operational logging—including timestamped run records, rotor ID tracking, temperature history, and fault event codes. All stored protocols retain metadata (user ID, date/time stamp, parameter version) to facilitate traceability under GLP or GMP frameworks. Language localization includes English, Chinese, Russian, and Portuguese UI options, ensuring cross-border deployment readiness. Though not FDA 21 CFR Part 11–validated out-of-the-box, the system’s deterministic behavior, non-volatile parameter storage, and tamper-evident error logs provide foundational elements for lab-specific validation packages required by regulatory auditors.

Applications

• Isolation of ASF viral DNA/RNA from oral fluid, blood, tissue homogenates, and environmental swabs prior to qPCR amplification.
• Clarification of lysates in nucleic acid extraction kits (e.g., silica-membrane or magnetic bead-based systems).
• Concentration of low-titer viral particles for electron microscopy or antigen capture assays.
• Separation of cellular debris and host genomic material to enrich pathogen-derived nucleic acids.
• Routine QC centrifugation in feed, meat, and carcass sampling programs aligned with OIE (WOAH) ASF surveillance guidelines.

FAQ

Does the HR/T16MM support rotor validation per ISO 20957-2?
Yes—the angular rotors are individually serialized and calibrated; RCF values are verified against ISO 20957-2 Annex B procedures during factory acceptance testing.
Can the centrifuge maintain −20 °C during extended runs (>2 h)?
Yes—its dual-stage condenser and insulated chamber enable sustained sub-zero operation across the full speed range, validated per IEC 61010-2-020 thermal load testing.
Is rotor imbalance detection performed continuously or only at startup?
Continuous real-time monitoring occurs throughout acceleration, steady-state rotation, and deceleration phases using integrated vibration spectrum analysis.
Are rotor lifetime and usage logs accessible to the operator?
Rotor usage cycles and cumulative runtime are stored in non-volatile memory and displayed upon rotor installation; service alerts trigger at predefined maintenance intervals.
Does the device comply with electromagnetic compatibility (EMC) directives for lab integration?
Yes—certified to EN 61326-1:2013 for EMC emissions and immunity in laboratory environments, including co-location with PCR cyclers and biosafety cabinets.