HNPM MZR-2521 Micro-Dosing Gear Pump
| Brand | HNPM |
|---|---|
| Origin | Germany |
| Model | MZR-2521 |
| Flow Rate | 0.0015–9 mL/min |
| Viscosity Range | 0.3–100 mPa·s (up to 1,000 mPa·s with optional configuration) |
| Precision | CV < 1% |
| Displacement Volume | 1.5 µL |
| Minimum Dose Volume | 0.25 µL |
| Speed Range | 1–6,000 rpm |
| Pressure Range | 0–1.5 bar differential |
| Max Inlet Pressure | 1 bar |
| Wetted Materials | SS 316L, ceramic, tungsten carbide, nickel-based alloys, epoxy |
| Shaft Seal | graphite-reinforced PTFE + SS 316L |
| Static Seals | FPM (optional EPDM/FFPM) |
| Motor | Brushed DC, 3 W nominal, 18 V, 16-pulse magnetic encoder |
| Interfaces | RS-232, CANopen (DSP 301/DSP 402) |
| Dimensions | Ø13 mm × 75 mm |
| Weight | ~56 g |
| Operating Temperature | −20 to +60 °C |
| Fluid Connections | 2 mm OD push-in fitting (manifold M2.1 optional) |
Overview
The HNPM MZR-2521 Micro-Dosing Gear Pump is a precision-engineered, compact volumetric displacement pump designed for ultra-low-volume, high-accuracy liquid handling in analytical instrumentation and automated laboratory systems. Based on rotary micro annular gear technology, it operates on the principle of positive displacement via synchronized ceramic-coated gear rotation within a precisely machined housing—ensuring minimal dead volume, negligible pulsation, and exceptionally low shear stress on sensitive fluids. Unlike peristaltic or syringe-based systems, the MZR-2521 delivers continuous, pulse-free flow without elastomer degradation or backflow drift, making it suitable for long-term unattended operation in regulated environments. Its sub-centimeter diameter and 75 mm length enable seamless integration into space-constrained platforms such as HPLC auxiliary solvent delivery modules, fuel cell test rigs, microfluidic assay workstations, and IVD cartridge interfaces.
Key Features
- Micro-annular gear architecture with ceramic-coated rotating elements ensures wear resistance, chemical inertness, and >10⁶ cycle service life under continuous operation.
- Flow stability maintained across full dynamic range: from 0.0015 mL/min (sub-microliter dosing at 1 rpm) up to 9 mL/min (6,000 rpm), with coefficient of variation (CV) consistently <1%—validated per ISO 5725-2 for repeatability.
- Low-shear fluid path geometry minimizes molecular degradation—critical for proteins, nanoparticles, and polymer solutions—while preserving sample integrity during transfer.
- Modular wetted material configuration: standard contact surfaces include AISI 316L stainless steel, technical ceramics (Al₂O₃/ZrO₂), tungsten carbide, and nickel-based alloys; static seals available in FPM (Viton®), EPDM, or perfluoroelastomer (FFPM) for aggressive solvents or bio-compatible applications.
- Digital control interface supports both RS-232 (ASCII protocol) and CANopen (conforming to CiA DSP 301 application layer and DSP 402 motion control profile), enabling deterministic real-time speed/position feedback and synchronization with PLC or LabVIEW-based orchestration systems.
Sample Compatibility & Compliance
The MZR-2521 is validated for use with low-to-medium viscosity liquids ranging from deionized water (0.3 mPa·s) to light lubricants and synthetic oils (≤100 mPa·s); extended-range configurations accommodate viscosities up to 1,000 mPa·s using optimized gear clearances and torque-enhanced motor variants. It complies with CE marking requirements under the EU Machinery Directive 2006/42/EC and Electromagnetic Compatibility Directive 2014/30/EU. For GxP-regulated workflows—including clinical diagnostics and pharmaceutical QC—the pump supports audit-trail-capable firmware (via CANopen object dictionary logging) and may be integrated into 21 CFR Part 11-compliant architectures when paired with qualified host software and electronic signature controls. All wetted materials meet USP Class VI and FDA 21 CFR 177.2420 standards for indirect food contact and biocompatibility.
Software & Data Management
Control and monitoring are implemented through HNPM’s proprietary PumpControl Suite (Windows/Linux), which provides graphical real-time flow visualization, programmable multi-step dosing sequences (including ramped acceleration/deceleration profiles), and exportable CSV logs timestamped to system clock with millisecond resolution. The CANopen interface enables direct mapping of pump status variables—including actual speed, accumulated volume, temperature sensor output (optional), and error flags—to standardized PDOs (Process Data Objects), facilitating interoperability with Beckhoff TwinCAT, Siemens SIMATIC S7, or National Instruments CompactRIO platforms. Firmware updates are performed over RS-232 using signed binary packages, ensuring traceability and version control in production validation documentation.
Applications
- Chromatography: Auxiliary solvent delivery in UHPLC gradient mixing, mobile phase degassing loop priming, and column washing protocols requiring stable sub-µL/min flow rates.
- Fuel Cell R&D: Precise metering of humidification water, catalyst ink slurries, and electrolyte solutions into MEA test cells under controlled pressure differentials.
- In Vitro Diagnostics: Reagent dispensing in cartridge-based immunoassays and nucleic acid extraction platforms where cross-contamination avoidance and dose reproducibility are critical.
- Materials Science: Controlled deposition of nanomaterial dispersions onto substrates during thin-film fabrication or additive manufacturing pre-processing stages.
- Environmental Monitoring: Low-flow sampling of aqueous matrices into online sensors (e.g., UV-Vis, conductivity, ion-selective electrodes) with minimal disturbance to laminar flow conditions.
FAQ
What is the minimum controllable dose volume per actuation?
The MZR-2521 achieves a minimum discrete dose of 0.25 µL, corresponding to one full gear revolution (1.5 µL displacement) operated at fractional speed with synchronized start/stop timing—achievable via external trigger input or internal command sequencing.
Can the pump handle corrosive solvents such as concentrated acids or halogenated hydrocarbons?
Standard configurations support methanol, acetonitrile, THF, and mineral oils. For aggressive media (e.g., HCl, HF, chloroform), custom wetted material sets—including Hastelloy C-276 gears, sapphire bearings, and FFPM seals—are available upon engineering review and compatibility testing.
Is the pump suitable for sterile or cleanroom applications?
Yes. The sealed, brushless-compatible motor design (with optional IP65-rated enclosure) and absence of lubricants in the fluid path allow for gamma irradiation sterilization (25 kGy) and ISO Class 5 cleanroom installation when paired with validated tubing and manifold assemblies.
How is calibration traceability established?
HNPM provides factory calibration certificates traceable to PTB (Physikalisch-Technische Bundesanstalt) standards, including gravimetric flow verification at three points across the operational range (0.01, 1.0, and 8.0 mL/min) using NIST-traceable mass balances and temperature-compensated timers.
Does the pump support bidirectional flow?
No. The MZR-2521 is unidirectional by mechanical design; reverse rotation is not supported due to asymmetric gear tooth geometry and seal orientation—however, flow reversal in system-level applications can be achieved via external valve manifolds.
