INNOTEG SPE Solid Phase Extraction Cartridges

Overview

INNOTEG SPE Solid Phase Extraction Cartridges are precision-engineered, pre-packed disposable devices designed for selective analyte isolation, matrix removal, and sample concentration in analytical laboratories. Based on the fundamental principle of liquid–solid partitioning—where analytes distribute between a stationary phase (sorbent) and a mobile phase (eluent)—these cartridges enable reproducible retention and elution through controlled surface chemistry interactions. Unlike traditional open-column chromatography, INNOTEG SPE cartridges integrate standardized geometry, consistent bed packing density, and rigorously validated sorbent lots to ensure inter-batch reliability and method transferability across food safety, environmental monitoring, clinical toxicology, and agricultural residue testing workflows.

Key Features

• Comprehensive sorbent portfolio covering reversed-phase (C18, C8), normal-phase (Silica, NH₂, Florisil), ion-exchange (MCX, MAX, WCX, WAX), mixed-mode (HLB, MCX/HLB hybrids), and specialty phases (GCB for chlorophyll removal, polyamide for aflatoxin cleanup, molecularly imprinted polymers for benzo[a]pyrene, DNPH for formaldehyde derivatization).
• High-purity silica backbone with tightly controlled particle size distribution and surface activity—ensuring low metal content, minimal silanol activity, and batch-to-batch consistency (RSD < 0.1% for breakthrough volume under standardized test conditions).
• Optimized cartridge architecture: uniform frit design, inert polypropylene housing, and calibrated flow dynamics enabling gravity-driven operation without vacuum manifolds or positive-pressure systems—reducing capital equipment dependency and consumables overhead.
• Scalable format range: from 60 mg/3 mL micro-columns for high-throughput screening to 2 g/12 mL preparative-scale cartridges for complex matrices such as soil extracts or lipid-rich biological homogenates.
• Trace-level contamination control: all cartridges undergo rigorous solvent-wash validation and are packaged in low-particulate cleanroom environments compliant with ISO Class 7 standards.

Sample Compatibility & Compliance

INNOTEG SPE cartridges support diverse sample types—including aqueous extracts (e.g., drinking water, urine), organic solvents (e.g., acetonitrile, ethyl acetate), and partially miscible matrices (e.g., QuEChERS supernatants, tissue homogenates). They are routinely applied in methods aligned with GB 5009.x (China National Food Safety Standards), HJ 478–2009 (Environmental Water Analysis), NY/T 761–2008 (Pesticide Residue Testing in Vegetables), and ISO 17025-accredited quality systems. While not certified to ISO/IEC 17025 themselves, the cartridges are manufactured under documented quality control protocols—including raw material traceability, lot-specific certificate of analysis (CoA), and stability testing per ICH Q5C guidelines. For regulated environments, they support GLP-compliant documentation when used within validated SOPs.

Software & Data Management

As passive consumables, INNOTEG SPE cartridges do not incorporate embedded electronics or firmware. However, they are fully compatible with LIMS-integrated sample preparation workflows. Each product SKU (e.g., 223-11002, 223-12004) is encoded with GS1-compliant barcodes supporting automated inventory tracking, chain-of-custody logging, and audit-ready traceability. Batch-specific CoAs include sorbent surface area (m²/g), pore size (nm), carbon load (%), and retention capacity (µg analyte/mg sorbent) where applicable—enabling digital method archiving and revalidation per FDA 21 CFR Part 11 requirements when paired with compliant electronic lab notebooks (ELNs).

Applications

• Food & Agriculture: Multi-residue pesticide analysis (QuEChERS-compatible cleanup), mycotoxin enrichment (aflatoxins, ochratoxin A), veterinary drug screening (tetracyclines, sulfonamides) in meat and milk.
• Environmental: PAHs and PCBs extraction from sediment and wastewater; perfluoroalkyl substances (PFAS) isolation from groundwater using WAX or mixed-mode HLB.
• Clinical & Forensic: Urinary amphetamines and opioids cleanup prior to LC-MS/MS; plasma vitamin D metabolite purification using C18/NH₂ dual-layer columns.
• Pharmaceutical: Impurity profiling of APIs via silica-based fractionation; residual solvent removal from synthetic intermediates.
• Botanical & TCM: Selective isolation of alkaloids (e.g., berberine), flavonoids, and terpenoids using TPH-specific or alumina-based cartridges per Chinese Pharmacopoeia monographs.

FAQ

Are INNOTEG SPE cartridges suitable for use in accredited testing laboratories?
Yes—they are designed to support method validation per ISO/IEC 17025 and are widely deployed in CNAS-accredited labs across China for routine compliance testing.
Do you provide certificates of analysis (CoA) for each batch?
Yes. Every production lot includes a CoA listing physical specifications, performance benchmarks (e.g., breakthrough volume for standard probe compounds), and QC test results.
Can these cartridges be used with automated SPE systems?
All standard 3 mL and 6 mL formats are mechanically compatible with major OEM platforms (e.g., Biotage Extrahera, Gilson ASPEC, Thermo Fisher Dionex AutoTrace) when fitted with universal adapter sleeves.
What is the shelf life and recommended storage condition?
Unopened cartridges retain full performance for 24 months when stored at 15–25°C in original sealed packaging, away from direct sunlight and volatile solvents.
Is method development support available?
INNOTEG provides application notes, comparative selectivity charts, and column selection guides based on analyte pKa, log P, and functional group reactivity—available upon request to technical support.