Jiayuan MX100-4A Microplate Shaker

Overview

The Jiayuan MX100-4A Microplate Shaker is an engineered platform for precise, reproducible orbital agitation of multi-well plates in life science laboratories. Designed specifically for compatibility with standard ANSI/SLAS-format microplates—including 96-well, 384-well, 24-well, and 48-well plates—the instrument employs a brushless DC motor coupled with microprocessor-based speed and timer control to deliver consistent orbital motion (3 mm diameter orbit) across all four plate positions. Its architecture supports applications requiring uniform suspension of cells, reagents, or assay components—such as ELISA development, cell-based assays, enzymatic reactions, antibody binding steps, and sample homogenization prior to downstream analysis (e.g., absorbance, fluorescence, or luminescence detection). Unlike generic benchtop shakers, the MX100-4A integrates plate-specific mechanical coupling and dynamic load compensation to maintain speed accuracy within ±5 rpm across its full operational range—even when operating at maximum capacity (four fully loaded plates).

Key Features

• Four independent plate platforms with rigid, low-profile clamping to minimize plate flexure and ensure consistent orbital transmission
• Brushless DC motor delivering high torque at low speeds and stable performance up to 1500 rpm—eliminating carbon brush wear and reducing electromagnetic interference
• LCD interface with real-time display of setpoint and actual speed, elapsed time, remaining time, and system status indicators
• One-knob rotary encoder for intuitive parameter entry—no menu navigation required; all settings confirmed with tactile feedback
• Programmable timer with resolution down to 1 minute, supporting durations from 1 min to 99 h 59 min; auto-stop with audible alert upon completion
• Integrated diagnostics including motor stall detection, thermal overload monitoring, and power anomaly recognition—all triggering visual alerts and optional audible alarms
• Universal AC input (100–240 V, 50/60 Hz) enabling seamless deployment in international labs without voltage conversion hardware

Sample Compatibility & Compliance

The MX100-4A accommodates all common microplate formats defined by ANSI SLAS-1–2022 and ANSI SLAS-4–2022 standards, including flat-bottom, round-bottom, and V-bottom 96-well plates; shallow-well 384-well plates; and tissue-culture-treated 24- and 48-well plates. It maintains mechanical stability under variable load conditions—verified per ISO 13485-aligned internal validation protocols for consistent coefficient of variation (CV) < 2.5% in speed repeatability across 100 consecutive runs. While not certified to IEC 61000-6-3 (EMC) or IEC 61010-1 (safety) as a standalone medical device, its design adheres to general laboratory equipment safety principles applicable to Class II, Pollution Degree 2 environments. The unit meets RoHS Directive 2011/65/EU requirements for hazardous substance restriction.

Software & Data Management

The MX100-4A operates as a standalone instrument with no proprietary software dependency. All configuration and operation occur via front-panel controls; no drivers, USB connectivity, or PC interface are provided or required. This architecture ensures compliance with GLP and GMP environments where uncontrolled software updates or networked data transfer may introduce validation complexity. Audit trails are maintained through physical logbooks or external lab information management systems (LIMS); the instrument itself records no timestamped event history. For regulated workflows requiring electronic records, integration is achieved via external programmable logic controllers (PLCs) or analog/digital I/O modules compliant with FDA 21 CFR Part 11 Annex 11 principles—subject to site-specific qualification.

Applications

• ELISA plate washing and incubation steps requiring uniform mixing without splashing or edge effects
• Suspension of adherent and non-adherent mammalian cell lines during passaging or assay setup
• Homogenization of viscous samples (e.g., lysates, serum-containing media) prior to centrifugation or filtration
• Enhancing antigen-antibody binding kinetics in immunoassays by optimizing mass transfer rates
• Facilitating dissolution and equilibration in high-throughput drug screening workflows using 384-well plates
• Supporting microbiological assays involving bacterial or yeast cultures in multi-well formats

FAQ

Does the MX100-4A support temperature control?
No. The MX100-4A is a non-incubated shaker. It does not integrate heating or cooling elements. For temperature-regulated agitation, consider dedicated microplate incubator-shakers.
Can it accommodate deep-well plates or PCR plates?
It supports ANSI/SLAS-compliant plates up to 14.5 mm height. Deep-well plates exceeding this dimension may interfere with lid clearance and are not recommended. Standard 96-well PCR plates (with skirted or semi-skirted profiles) are compatible if within height tolerance.
Is speed calibration traceable to NIST or other national standards?
The unit includes factory calibration documentation. End-user recalibration requires an external tachometer; no built-in self-calibration routine is provided.
What maintenance is required for long-term reliability?
No scheduled maintenance is required beyond periodic cleaning of the plate platforms and ventilation grilles. The brushless motor has no consumable parts and is rated for >20,000 hours of continuous operation.
Does the device meet FDA or CE regulatory requirements for use in clinical labs?
It carries no CE marking or FDA 510(k) clearance. Its use in clinical diagnostic workflows falls under the responsibility of the end-user’s quality system validation process.