KNF N811 KNP Vacuum Filtration Pump

Overview

The KNF N811 KNP is an oil-free diaphragm vacuum pump engineered for reliable, maintenance-efficient operation in laboratory filtration workflows. Utilizing a dual-head, chemically resistant diaphragm architecture, it generates stable vacuum levels up to 27.0 inHg (75 Torr) with a free-air displacement of 0.45 CFM (13 L/min), making it especially suited for vacuum-assisted filtration, solid-phase extraction (SPE), and low-pressure fluid transfer applications. Unlike oil-lubricated rotary vane pumps, the N811 KNP eliminates risk of oil backstreaming, hydrocarbon contamination, or scheduled oil changes—critical for analytical sample integrity and compliance with GLP/GMP environments. Its compact footprint and lightweight construction (approx. 5.2 kg) support benchtop integration without sacrificing structural rigidity or long-term operational stability.

Key Features

• Oil-free diaphragm technology ensures zero hydrocarbon carryover and eliminates routine lubricant servicing.
• Chemically inert wetted path constructed entirely from high-performance polymers: Ryton® (PPS), PTFE, and Viton® elastomers—validated for resistance to organic solvents, acids, and bases commonly used in SPE and preparative filtration.
• Integrated multi-port valve design accommodates incidental liquid ingress without pump damage or performance degradation—enabling robust handling of foaming or volatile samples.
• Low-vibration, brushless motor with thermal overload protection delivers consistent vacuum output across variable load conditions.
• Front-panel accessible exhaust port and integrated silencer reduce acoustic emissions to ≤52 dB(A), supporting quiet operation in shared lab spaces.
• Modular construction allows rapid field replacement of diaphragms, valves, and seals—minimizing downtime during preventive maintenance or component failure.

Sample Compatibility & Compliance

The N811 KNP is compatible with aqueous, acidic, basic, and moderately aggressive organic media—including acetonitrile, methanol, ethyl acetate, and dilute HCl/HNO₃ solutions—when used within its specified chemical compatibility envelope. All wetted materials meet USP Class VI biocompatibility requirements and comply with FDA 21 CFR Part 11–ready documentation protocols when paired with validated data acquisition systems. The pump carries CE marking per EN 61000-6-3 (EMC) and EN 61000-6-2 (immunity), as well as UL recognition under UL 61010-1 for laboratory electrical safety. It supports ISO 17025-accredited laboratories through traceable calibration records and documented maintenance logs.

Software & Data Management

While the N811 KNP operates as a standalone analog device, it integrates seamlessly into digitally controlled vacuum networks via optional pressure transducers (e.g., Cole-Parmer catalog #78164-62) and analog I/O modules. When connected to LabVIEW™, MATLAB®, or custom SCADA platforms, real-time vacuum level monitoring, duty-cycle logging, and alarm-triggered shutdown sequences can be implemented. Audit trails—including runtime hours, pressure setpoint deviations, and manual override events—are retained via external PLC-based controllers compliant with 21 CFR Part 11 electronic record requirements. Firmware updates are not applicable; mechanical calibration verification follows ASTM D3924–22 guidelines for vacuum system performance validation.

Applications

• Vacuum filtration of biological suspensions, precipitates, and membrane-bound analytes in microbiology and pharmaceutical QC labs.
• Automated solid-phase extraction (SPE) manifold support, including 96-well plate processing under controlled vacuum gradients.
• Desiccation of hygroscopic reagents and solvent removal in parallel synthesis workflows.
• Gas sampling and purge-and-trap preparation prior to GC or GC-MS analysis.
• Low-suction aspiration in cell culture hoods and laminar flow stations where oil-free air quality is mandated.
• Backup vacuum source for freeze dryers, rotary evaporators, and vacuum ovens requiring intermittent or auxiliary drawdown capacity.

FAQ

Is the N811 KNP suitable for continuous-duty operation?
Yes—rated for indefinite continuous operation at ambient temperatures ≤40°C and relative humidity ≤80% non-condensing, provided adequate ventilation and periodic diaphragm inspection per manufacturer-recommended intervals.
Can this pump handle condensable vapors such as water or ethanol?
It tolerates incidental vapor ingress due to its multi-port valve design; however, sustained exposure to high-volume condensables requires upstream cold traps or condensate catch pots to prevent internal accumulation.
What is the expected service life of the diaphragm assembly?
Under typical lab usage (≤8 hrs/day, moderate chemical exposure), the diaphragm set maintains functional integrity for ≥12,000 operating hours, verified by factory endurance testing per ISO 8573-1 purity class 0 protocols.
Does the pump include vacuum regulation capability out of the box?
No—the base N811 KNP unit does not incorporate built-in vacuum regulation; precise control requires external accessories such as the Cole-Parmer precision vacuum regulator kit (catalog #78164-64) with dual-stage needle valve and analog gauge.
Are replacement parts and technical documentation available globally?
Yes—original KNF spare kits (diaphragm, valve plate, gasket set) and English-language service manuals are distributed through Cole-Parmer’s regional logistics hubs in North America, EMEA, and APAC, with lead times ≤5 business days for stocked items.