MEMMERT INE800 Forced-Air Incubator

Overview

The MEMMERT INE800 is a high-precision, microprocessor-controlled forced-air incubator engineered for reproducible, GLP-compliant temperature conditioning of biological, microbiological, and cell-based samples. Unlike natural convection units, the INE800 employs an actively regulated air circulation system with adjustable fresh-air admixture via throttling valve and motorized damper control (on UF/SF variants), enabling precise management of humidity dynamics and thermal homogeneity across the entire 749 L working chamber. Its core thermal architecture integrates four-sided stainless steel heating elements, full cavity insulation, and dual A-class Pt100 resistance thermometers operating in redundant 4-wire configuration—ensuring continuous cross-validation of temperature readings and uninterrupted operation even if one sensor fails. The unit operates across a broad temperature range of 20 °C to 250 °C (U/S variant; optional up to 300 °C), with standard I-series models optimized for life science applications (20–70 °C), delivering exceptional stability: ±0.05 °C at 37 °C (DIN 12880) and ±0.6 °C uniformity across the chamber at that setpoint.

Key Features

• Microprocessor-based PID fuzzy logic controller with integrated self-diagnostic system and error indication
• Dual A-class Pt100 sensors (4-wire circuitry) for real-time redundancy and fault-tolerant monitoring
• 7-day programmable timer with real-time clock; temperature ramps and holds programmable to the minute
• Up to 4 independent time-temperature segments per program; repeat cycles configurable from 1 to 99 times or infinite loop
• 1024 kB internal ring-buffer data logger compliant with GLP requirements (timestamped temperature, setpoints, alarms, events)
• Triple-tier overtemperature protection: (1) electronic TWW controller (Class 3.1, fixed +3 °C offset), (2) mechanical TB limiter (+10 °C above max chamber rating), (3) independent microprocessor-based thermal watchdog
• Stainless steel interior (1.4301 / ASTM 304), deep-drawn, easy-clean chamber with integrated multi-hole stainless steel shelf (load capacity: 30 kg/shelf, 160 kg total)
• RS232 interface and free Celsius 2007 software for remote programming, real-time monitoring, and export of validated CSV/Excel logs
• Included 37 °C calibration certificate traceable to national standards; optional STERI chip card for automated 160 °C sterilization cycles

Sample Compatibility & Compliance

The INE800 accommodates diverse sample formats—including Petri dishes, flasks, multiwell plates, and tissue culture vessels—within its spacious 749 L chamber (W 1040 × H 1200 × D 600 mm). Its stainless steel construction (interior and exterior), double-locking insulated door with inner glass panel, and corrosion-resistant galvanized rear panel ensure long-term reliability in demanding lab environments. The system meets critical regulatory expectations for laboratory equipment: it supports audit-ready data integrity per FDA 21 CFR Part 11 (when used with Celsius 2007 v3.0+ and appropriate IT controls), adheres to DIN 12880 for temperature uniformity testing, and includes factory-issued calibration documentation aligned with ISO/IEC 17025 principles. Optional accessories—such as humidity control modules, CO₂ integration kits, and validated sterilization protocols—extend compliance into GMP and clinical research workflows.

Software & Data Management

Celsius 2007 software provides full bidirectional communication with the INE800 via RS232, enabling unlimited ramp/soak profiles, multi-parameter scheduling (temperature, airflow, damper position), and secure data archival. Logged data—including actual vs. setpoint temperatures, alarm timestamps, and diagnostic codes—is stored in a tamper-evident circular buffer (1024 kB ≈ 6 months at 1-min intervals). Export options include PCL3-compatible printer output (via parallel port adapter) and timestamped CSV files suitable for LIMS integration. Firmware updates, language localization (D/UK/E/F/I), and user-access level configuration (operator/administrator) are managed directly through the software interface. All logged entries include digital signatures, session IDs, and change history—supporting ALCOA+ data governance frameworks.

Applications

The INE800 serves as a primary platform for controlled-environment applications requiring strict thermal fidelity and regulatory traceability: bacterial and fungal culture incubation (e.g., ISO 4833-1, USP ); enzyme activity assays; stability testing per ICH Q1A(R2); cell line expansion and passaging; pharmaceutical dissolution support; and accelerated aging studies. Its extended high-temperature capability also supports materials testing (e.g., polymer curing validation per ASTM D5370) and dry-heat depyrogenation protocol development. The programmable ramp-and-hold functionality makes it ideal for simulating physiological thermal gradients, circadian rhythm studies, and thermal stress response profiling in model organisms.

FAQ

What temperature accuracy and uniformity does the INE800 achieve at 37 °C?
At 37 °C, the INE800 achieves a temperature deviation of ≤±0.05 °C and chamber uniformity of ≤±0.6 °C (per DIN 12880), verified by dual Pt100 sensors and included calibration certificate.
Is the INE800 compatible with FDA 21 CFR Part 11 requirements?
Yes—when deployed with Celsius 2007 software v3.0+, configured user authentication, electronic signatures, and audit-trail enabled, the system satisfies electronic record and signature criteria for regulated environments.
Can the internal chamber be sterilized in situ?
Yes—using the optional STERI chip card, users can execute automated 160 °C dry-heat sterilization cycles (4 h duration) without disassembly or external validation equipment.
How many temperature programs can be stored internally?
The controller stores up to 4 user-defined multi-segment programs; unlimited profiles may be created, edited, and executed remotely via Celsius 2007 software.
What safety certifications does the INE800 hold?
It carries CE marking, complies with IEC 61010-1 (Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use), and meets EMC Directive 2014/30/EU standards.