Merck Millipore Elix 20 Ultra Pure Water System
| Origin | France |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Elix 20 |
| Pricing | Upon Request |
Overview
The Merck Millipore Elix 20 Ultra Pure Water System is an integrated, point-of-use or centralized water purification platform engineered for continuous production of Type II analytical-grade pure water—meeting or exceeding international standards including ASTM D1193, ISO 3696:1987 (Grade 2), CLSI (formerly NCCLS) guidelines, USP , and EP 2.2.45. Leveraging a multi-stage purification architecture—including pre-treatment, reverse osmosis (RO), electrodeionization (EDI), and optional UV oxidation—the Elix 20 delivers up to 20 L/h of high-resistivity water at >5 MΩ·cm (25 °C, temperature-compensated) with TOC <30 ppb and bacterial counts <10 CFU/mL. Its core innovation lies in the patented Elix continuous current deionization module, which enables uninterrupted regeneration of ion exchange media without chemical intervention, ensuring stable conductivity control and extended consumable service life. Designed for laboratory environments requiring reliable, low-maintenance feedwater for downstream ultra-pure systems (e.g., Milli-Q® or Super-Q® units), clinical diagnostics, or pharmaceutical process support, the Elix 20 operates across ambient inlet temperatures of 7–30 °C and tolerates variable municipal feedwater quality without mandatory external softening.
Key Features
- Patented Elix continuous current deionization (EDI) module providing real-time, chemical-free regeneration of ion exchange resins—eliminating downtime and reducing operational cost per liter.
- Integrated dual-parameter monitoring: high-accuracy temperature-compensated resistivity sensor (0.01–18.2 MΩ·cm range) and on-line TOC analyzer (detection limit <10 ppb, quantification range 1–1000 ppb).
- UV lamp (254 nm) integrated into the polishing loop to suppress microbial proliferation and oxidize trace organics—critical for cell culture, molecular biology, and endotoxin-sensitive applications.
- Modular pre-treatment configuration with user-replaceable cartridges (carbon, sediment, optional softening) tailored to local feedwater hardness, chlorine, and particulate load.
- Full system control via intuitive touchscreen interface with configurable alarms, event logging, and password-protected user access levels (Operator, Technician, Administrator).
- Scalable architecture compatible with centralized distribution networks—supports integration of booster pumps, loop circulation modules, ASM (Automatic Sample Monitor) valves, and remote TOC/resistivity nodes.
Sample Compatibility & Compliance
The Elix 20 is validated for use with standard municipal tap water (chlorinated or chloraminated), well water (with appropriate pre-filtration), and pre-treated industrial feed sources. It complies with GLP/GMP-aligned data integrity requirements: all critical parameters (resistivity, TOC, UV intensity, flow rate, pressure differentials) are timestamped and stored with audit trail functionality. The system supports 21 CFR Part 11-compliant electronic records when paired with Millipore’s LabManager™ software. Certificates of Conformance (CoC) and IQ/OQ documentation packages are available upon request for regulated environments. All wetted materials meet USP Class VI biocompatibility standards; tubing and housings are constructed from pharmaceutical-grade polypropylene and PVDF.
Software & Data Management
The embedded control firmware enables local data export via USB or Ethernet (Modbus TCP/IP). Optional LabManager™ software provides centralized fleet monitoring, predictive maintenance alerts based on cartridge saturation algorithms, and automated report generation compliant with ISO/IEC 17025 and FDA 21 CFR Part 11 Annex 11 requirements. Historical trend graphs for resistivity, TOC, and UV lamp output are exportable in CSV or PDF format. All system events—including alarm triggers, user logins, and consumable replacement confirmations—are retained for ≥12 months with tamper-evident timestamps and operator ID tagging.
Applications
- Preparation of microbiological growth media, PBS buffers, and HPLC mobile phases requiring low ionic background and minimal organic contamination.
- Feedwater supply for Milli-Q® Integral, Advantage A10, or Super-Q® ultrapure water systems—reducing upstream RO membrane fouling and extending final polish cartridge lifetime.
- Pharmaceutical manufacturing support: preparation of WFI (Water for Injection) precursor streams, cleaning validation solutions, and excipient diluents under cGMP conditions.
- Automated analyzers (e.g., clinical chemistry, immunoassay platforms) and LC-MS instrumentation requiring consistent low-conductivity rinse and diluent water.
- Hydroponic research setups and plant tissue culture labs where silica removal (>99.9%) and endotoxin-free operation are essential.
- Environmental testing laboratories performing EPA Method 160.1 or ISO 14851 compliance water analysis.
FAQ
What is the maximum daily output capacity of the Elix 20 system?
The Elix 20 is rated for continuous operation delivering up to 480 L/day (20 L/h) under specified ambient conditions (7–30 °C inlet temperature). Actual throughput may vary with feedwater temperature, pressure, and ionic load.
Does the Elix 20 require pretreatment for hard water sources?
While the system incorporates scale-inhibiting EDI technology and tolerates moderate hardness (<300 ppm CaCO₃), installation of an optional softening cartridge is recommended for feedwater exceeding 200 ppm hardness to maximize RO membrane lifespan and maintain optimal recovery rates.
Can the Elix 20 be connected to a building-wide purified water distribution loop?
Yes—the Elix 20 supports both standalone and centralized configurations. It includes dedicated ports for integration with circulation pumps, loop temperature sensors, and distributed ASM sampling points, enabling full parameter oversight across multi-point networks.
How frequently must consumables be replaced?
Pre-filter cartridges typically require replacement every 3–6 months depending on feedwater quality; the Elix EDI module has a service life of 2–3 years under normal operation. System software provides real-time saturation indicators and proactive replacement reminders.
Is TOC monitoring performed continuously or intermittently?
TOC measurement is conducted continuously in real time using a six-wavelength UV absorbance algorithm with automatic zero calibration—ensuring uninterrupted verification of organic contaminant removal efficiency.
