Merck Millipore RiOs 16 Ultra Pure Water System
| Origin | France |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | RiOs 16 |
| Pricing | Upon Request |
Overview
The Merck Millipore RiOs 16 Ultra Pure Water System is a compact, integrated laboratory water purification platform engineered to produce consistent, high-quality Type III (ISO 3696 / ASTM D1193 Grade III) purified water directly from municipal tap feedwater. Utilizing a multi-stage purification architecture—comprising prefiltration, high-recovery reverse osmosis (RO), and post-RO polishing—the RiOs 16 delivers stable output at up to 16 L/h with ±15% flow accuracy under standard operating conditions. Its design prioritizes operational reliability, low total cost of ownership, and compliance-driven performance in regulated environments. The system operates without external pressurization or pretreatment infrastructure, making it suitable for decentralized deployment across core laboratory workspaces, including central utility rooms, QC labs, and shared instrumentation facilities.
Key Features
- Integrated prefiltration cartridge housing three distinct media: sediment filter, activated carbon block, and scale inhibitor—enabling robust protection of the RO membrane against chlorine, particulates, and hardness ions.
- Advanced high-recovery RO module with intelligent recirculation loop, achieving up to 38% recovery rate and reducing wastewater generation by approximately 50% compared to conventional single-pass RO systems.
- Self-diagnostic RO maintenance mode with guided user prompts via backlit LCD interface; no specialized tools required for routine membrane cleaning or replacement.
- Optional 254 nm UV lamp (Cat. No. UFC8000000) for enhanced microbial control—critical for applications involving cell culture media preparation, HPLC mobile phase dilution, or low-endotoxin requirements.
- Compact footprint (45.7 × 25.5 × 31.5 cm) and lightweight chassis (15 kg) support benchtop installation with minimal spatial impact and plug-and-play electrical connectivity (100–240 VAC, 50/60 Hz).
- Full-system operation controlled via intuitive membrane keypad; real-time display of feed pressure, RO rejection rate, conductivity, and system status codes.
Sample Compatibility & Compliance
The RiOs 16 is validated for continuous production of Type III water meeting ISO 3696:2017, ASTM D1193-20, and CLSI EP22-A2 specifications. It serves as primary feedwater for downstream ultra-pure systems (e.g., Milli-Q® IQ 7000 series), autoclaves, glassware washers, and environmental chambers. All internal wetted components comply with USP Class VI biocompatibility standards. Electrical safety certification includes UL 61010-1 (E216983) and cUL listing for Laboratory Use Electrical Equipment. Electromagnetic compatibility conforms to EU directives 2014/30/EU (EMC) and 2014/35/EU (LVD). Manufacturing adheres to ISO 9001:2015 quality management and ISO 14001:2015 environmental management systems.
Software & Data Management
While the RiOs 16 does not incorporate networked software or remote monitoring capabilities, its embedded firmware supports full audit trail functionality through non-volatile memory logging of critical events—including cartridge replacement timestamps, RO performance metrics, and alarm history. Data export is accessible via USB port using proprietary diagnostic utility (RiOs Service Tool v3.2+), enabling GLP-compliant record retention for internal QA review. Firmware updates are performed offline via secure USB key, ensuring integrity and traceability per FDA 21 CFR Part 11 Annex 11 principles where applicable.
Applications
- Feedwater supply for Milli-Q® ultrapure water systems requiring consistent low-conductivity input (≤ 5 µS/cm).
- Final rinse water for analytical glassware cleaning in ICP-MS, AAS, and GC-MS laboratories.
- Make-up water for steam sterilizers, humidifiers, and washer-disinfectors operating under ISO 15883 and EN 285 standards.
- Buffer and reagent preparation for ELISA, PCR setup, and routine microbiological assays.
- General-purpose lab use including media preparation, titration, and spectrophotometric blanking.
FAQ
What feedwater quality is required for optimal RiOs 16 performance?
Municipal tap water with total dissolved solids (TDS) ≤ 500 ppm, free chlorine ≤ 2 ppm, and turbidity ≤ 1 NTU is recommended. Hardness should be maintained below 200 ppm CaCO₃ to prevent scaling.
Can the RiOs 16 be connected to a storage tank?
Yes—optional pressure switch kits and level sensors enable integration with stainless steel or polyethylene reservoirs for gravity-fed distribution networks.
Is the system compliant with GMP/GLP documentation requirements?
It supports basic traceability through on-device event logs and service tool-generated reports; however, full electronic signature and user access control require integration with a validated LIMS or ELN platform.
How often must consumables be replaced?
Prefilter cartridges require replacement every 6 months or after 1,500 L processed; RO membranes typically last 2–3 years depending on feedwater composition and usage intensity.
Does the RiOs 16 include endotoxin removal capability?
No—endotoxin reduction is not part of the RiOs 16’s purification profile. For endotoxin-sensitive applications, pairing with a Milli-Q® system equipped with ultrafiltration or dual-wavelength UV oxidation is advised.
